Journal of The Electrochemical Society,
Journal Year:
2024,
Volume and Issue:
171(8), P. 087520 - 087520
Published: Aug. 1, 2024
5-Fluorouracil
(5-FU)
is
widely
used
in
the
treatment
of
various
cancers,
necessitating
accurate
and
sensitive
detection
techniques.
Hybrid
materials,
combining
organic
inorganic
components,
offer
superior
electrochemical
characteristics,
including
enhanced
conductivity
stability.
Herein,
NiO
nanorods
(NiONRs)
were
synthesized
using
Mangifera
indica
leaves
extract
decorated
with
chitosan
curcumin
analog
Schiff
base
(Cs-Cur-A).
The
characterization
NiONRs
Cs-Cur-A
investigated
through
different
techniques
FT-IR,
1
HNMR,
XRD,
SEM,
EDX.
A
selective
sensor
to
determine
5-FU
was
elucidated
a
Cs-Cur-A/NiONRs
modified
glassy
carbon
electrode
(GCE).
anodic
peak
current
greatly
at
Cs-Cur-A/NiONRs/GCE
pH
7.0
scan
rate
50
mV
s
−1
.
According
chronoamperometric
measurements,
value
diffusion
coefficient
(D)
estimated
be
2.96
×
10
−6
cm
2
Using
differential
pulse
voltammetry
(DPV),
fabricated
exhibits
wide
linear
range
(0.1–150.0
μM)
low
limit
(21.75
nM).
Moreover,
proposed
successfully
applied
blood
serum
urine
samples
high
reproducibility,
repeatability,
selectivity.
Chemosensors,
Journal Year:
2025,
Volume and Issue:
13(2), P. 65 - 65
Published: Feb. 11, 2025
This
review
highlights
recent
advances
in
the
development
of
electrochemical
sensors
and
biosensors
for
detecting
pharmaceutical
contaminants
water
samples,
including
surface
water,
wastewater,
bottled
water.
The
electrode
modification
materials—such
as
nanomaterials,
conductive
polymers,
eco-friendly
nanocomposites—have
shown
notable
improvements
sensor
sensitivity
selectivity,
enabling
detection
various
compounds,
diclofenac,
ibuprofen,
antibiotics,
hormones.
Future
research
directions
suggest
use
nanocomposites,
multiplexed
platforms
simultaneous
contaminant
detection,
integration
into
portable
devices
situ
monitoring.
Additionally,
integrating
with
specific
biomolecules
IoT
technology
can
expand
their
applicability,
continuous
efficient
quality
monitoring,
thus
supporting
public
health
environmental
protection.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(1), P. 162 - 162
Published: Jan. 4, 2024
Dimetridazole
(DMZ)
is
a
derivative
of
nitroimidazole
and
veterinary
drug
used
as
an
antibiotic
to
treat
bacterial
or
protozoal
infections
in
poultry.
The
residues
DMZ
cause
harmful
side
effects
human
beings.
Thus,
we
have
constructed
superior
electrocatalyst
for
detection.
A
copper
(Cu)-integrated
poly(aniline)
(PANI)
(PANI-Cu@BSA)
was
prepared
by
using
one-step
method
biomimetic
mineralization
polymerization
bovine
serum
albumin
(BSA)
stabilizer.
Then,
the
synthesized
PANI-Cu@BSA
encapsulated
with
reduced
graphene
oxide
(rGO)
ultrasonication
method.
PANI-Cu@BSA/rGO
nanocomposite
had
water
dispersibility,
high
electrical
conductivity,
nanoscale
particles.
Moreover,
nanocomposite-modified,
screen-printed
carbon
electrode
sensitive
electrochemical
detection
DMZ.
In
phosphate
buffer
solution,
PANI-Cu@BSA/rGO/SPCE
displayed
current
intensity
greater
than
PANI-Cu@BSA/SPCE,
rGO/SPCE,
bare
SPCE.
This
because
combined
rGO
increases
fast
electron
transfer
between
analyte,
this
synergy
results
analyte–electrode
junctions
extraordinary
conductivity
active
surface
areas.
low
limit,
sensitivity,
linear
range
1.78
nM,
5.96
μA
μM−1
cm−2,
0.79
2057
μM,
respectively.
selective
examination
achieved
interfering
molecules,
showed
excellent
selectivity,
stability,
repeatability,
practicability.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(8), P. 1043 - 1043
Published: Aug. 6, 2024
Chitosan
nanoparticles
(CSNPs)
are
promising
vehicles
for
targeted
and
controlled
drug
release.
Recognized
their
biodegradability,
biocompatibility,
low
toxicity,
ease
of
production,
CSNPs
represent
an
effective
approach
to
delivery.
Encapsulating
drugs
within
(NPs)
provides
numerous
benefits
compared
free
drugs,
such
as
increased
bioavailability,
minimized
toxic
side
effects,
improved
delivery,
the
incorporation
additional
features
like
release,
imaging
agents,
combination
therapies
with
multiple
drugs.
Keys
parameters
in
nanomedicines
loading
content
efficiency.
Most
current
NP
systems
struggle
loading,
presenting
a
significant
challenge
field.
This
review
summarizes
recent
research
on
developing
high
capacity,
focusing
various
synthesis
strategies.
It
examines
CSNP
using
different
materials
providing
details
methods,
loadings,
encapsulation
efficiencies,
release
profiles,
stability,
applications
Additionally,
discusses
factors
affecting
valuable
guidelines
future
CSNPs’
development.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
13
Published: March 20, 2025
Electrospinning
is
a
type
of
electrohydrodynamics
that
utilizes
high-voltage
electrostatic
force
to
stretch
polymer
solution
into
nanofibers
under
the
influence
an
electric
field,
with
most
fibers
falling
onto
collector.
This
technology
favored
by
researchers
across
various
fields
due
its
simple
and
inexpensive
device
for
producing
in
straightforward
manner.
Nanofibers
prepared
through
electrospinning
have
high
specific
surface
area
porosity.
shows
extensive
potential,
especially
within
biomedical
sensors.
article
provides
systematic
overview
factors
influencing
electrospinning,
parameters
process,
types
electrospun
nanofibers,
applications
field
sensors,
including
wearable
pressure
glucose
The
paper
summarizes
research
progress
this
points
out
direction
development
technology,
as
well
future
challenges.