Electrochemical Nanomolar Determiantion of the Anticancer Drug 5-Fluorouracil Using Chitosan Curcumin Schiff Base-Decorated NiO Nanorods Synthesized with Green Method DOI Creative Commons
Mohamed Abd-Elsabour, Mortaga M. Abou–Krisha,

Fatehy M. Abdel-Haleem

et al.

Journal of The Electrochemical Society, Journal Year: 2024, Volume and Issue: 171(8), P. 087520 - 087520

Published: Aug. 1, 2024

5-Fluorouracil (5-FU) is widely used in the treatment of various cancers, necessitating accurate and sensitive detection techniques. Hybrid materials, combining organic inorganic components, offer superior electrochemical characteristics, including enhanced conductivity stability. Herein, NiO nanorods (NiONRs) were synthesized using Mangifera indica leaves extract decorated with chitosan curcumin analog Schiff base (Cs-Cur-A). The characterization NiONRs Cs-Cur-A investigated through different techniques FT-IR, 1 HNMR, XRD, SEM, EDX. A selective sensor to determine 5-FU was elucidated a Cs-Cur-A/NiONRs modified glassy carbon electrode (GCE). anodic peak current greatly at Cs-Cur-A/NiONRs/GCE pH 7.0 scan rate 50 mV s −1 . According chronoamperometric measurements, value diffusion coefficient (D) estimated be 2.96 × 10 −6 cm 2 Using differential pulse voltammetry (DPV), fabricated exhibits wide linear range (0.1–150.0 μM) low limit (21.75 nM). Moreover, proposed successfully applied blood serum urine samples high reproducibility, repeatability, selectivity.

Language: Английский

Electrochemical Sensors and Biosensors for the Detection of Pharmaceutical Contaminants in Natural Waters—A Comprehensive Review DOI Creative Commons
Alexandra Virginia Bounegru, Ancuța Dinu, Cătălina Iticescu

et al.

Chemosensors, Journal Year: 2025, Volume and Issue: 13(2), P. 65 - 65

Published: Feb. 11, 2025

This review highlights recent advances in the development of electrochemical sensors and biosensors for detecting pharmaceutical contaminants water samples, including surface water, wastewater, bottled water. The electrode modification materials—such as nanomaterials, conductive polymers, eco-friendly nanocomposites—have shown notable improvements sensor sensitivity selectivity, enabling detection various compounds, diclofenac, ibuprofen, antibiotics, hormones. Future research directions suggest use nanocomposites, multiplexed platforms simultaneous contaminant detection, integration into portable devices situ monitoring. Additionally, integrating with specific biomolecules IoT technology can expand their applicability, continuous efficient quality monitoring, thus supporting public health environmental protection.

Language: Английский

Citations

1

Protein-Aided Synthesis of Copper-Integrated Polyaniline Nanocomposite Encapsulated with Reduced Graphene Oxide for Highly Sensitive Electrochemical Detection of Dimetridazole in Real Samples DOI Open Access

Kartik Behera,

Bhuvanenthiran Mutharani,

Yen‐Hsiang Chang

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(1), P. 162 - 162

Published: Jan. 4, 2024

Dimetridazole (DMZ) is a derivative of nitroimidazole and veterinary drug used as an antibiotic to treat bacterial or protozoal infections in poultry. The residues DMZ cause harmful side effects human beings. Thus, we have constructed superior electrocatalyst for detection. A copper (Cu)-integrated poly(aniline) (PANI) (PANI-Cu@BSA) was prepared by using one-step method biomimetic mineralization polymerization bovine serum albumin (BSA) stabilizer. Then, the synthesized PANI-Cu@BSA encapsulated with reduced graphene oxide (rGO) ultrasonication method. PANI-Cu@BSA/rGO nanocomposite had water dispersibility, high electrical conductivity, nanoscale particles. Moreover, nanocomposite-modified, screen-printed carbon electrode sensitive electrochemical detection DMZ. In phosphate buffer solution, PANI-Cu@BSA/rGO/SPCE displayed current intensity greater than PANI-Cu@BSA/SPCE, rGO/SPCE, bare SPCE. This because combined rGO increases fast electron transfer between analyte, this synergy results analyte–electrode junctions extraordinary conductivity active surface areas. low limit, sensitivity, linear range 1.78 nM, 5.96 μA μM−1 cm−2, 0.79 2057 μM, respectively. selective examination achieved interfering molecules, showed excellent selectivity, stability, repeatability, practicability.

Language: Английский

Citations

5

Drug Loading in Chitosan-Based Nanoparticles DOI Creative Commons
Yedi Herdiana, Ellin Febrina, Siti Nurhasanah

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(8), P. 1043 - 1043

Published: Aug. 6, 2024

Chitosan nanoparticles (CSNPs) are promising vehicles for targeted and controlled drug release. Recognized their biodegradability, biocompatibility, low toxicity, ease of production, CSNPs represent an effective approach to delivery. Encapsulating drugs within (NPs) provides numerous benefits compared free drugs, such as increased bioavailability, minimized toxic side effects, improved delivery, the incorporation additional features like release, imaging agents, combination therapies with multiple drugs. Keys parameters in nanomedicines loading content efficiency. Most current NP systems struggle loading, presenting a significant challenge field. This review summarizes recent research on developing high capacity, focusing various synthesis strategies. It examines CSNP using different materials providing details methods, loadings, encapsulation efficiencies, release profiles, stability, applications Additionally, discusses factors affecting valuable guidelines future CSNPs’ development.

Language: Английский

Citations

5

A review on exploring the potential of PVA and chitosan in biomedical applications: A focus on tissue engineering, drug delivery and biomedical sensors DOI

D Manohar,

Ravi Shanker Babu,

B. Vijaya

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137318 - 137318

Published: Nov. 14, 2024

Language: Английский

Citations

5

A novel molecularly rabeprazole imprinted electrochemical sensor based on Fe3O4@SiO2–MWNTs nanocomposite DOI
Zeinab Khalili, Azizollah Nezhadali

Microchemical Journal, Journal Year: 2024, Volume and Issue: 199, P. 109926 - 109926

Published: Jan. 8, 2024

Language: Английский

Citations

4

Design and synthesis of polypyrrole conductive ink based on sulfated chitosan for bactericide carbendazim detection DOI

Bhuvanenthiran Mutharani,

Palraj Ranganathan, Yen‐Hsiang Chang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 331, P. 121800 - 121800

Published: Jan. 12, 2024

Language: Английский

Citations

4

Simultaneous detection of Cu(II) and Pb(II) in the Danube river using a bismuth film modified glassy carbon rotating disk electrode DOI
Alexandra Virginia Bounegru, L. Georgescu, Cătălina Iticescu

et al.

Journal of Electroanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118924 - 118924

Published: Jan. 1, 2025

Language: Английский

Citations

0

Electrospun nanofibers and their application as sensors for healthcare DOI Creative Commons
Yiting Zhao, Jie Huang, Xingjian Yang

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: March 20, 2025

Electrospinning is a type of electrohydrodynamics that utilizes high-voltage electrostatic force to stretch polymer solution into nanofibers under the influence an electric field, with most fibers falling onto collector. This technology favored by researchers across various fields due its simple and inexpensive device for producing in straightforward manner. Nanofibers prepared through electrospinning have high specific surface area porosity. shows extensive potential, especially within biomedical sensors. article provides systematic overview factors influencing electrospinning, parameters process, types electrospun nanofibers, applications field sensors, including wearable pressure glucose The paper summarizes research progress this points out direction development technology, as well future challenges.

Language: Английский

Citations

0

Chitosan, derivatives, and its nanoparticles: Preparation, physicochemical properties, biological activities, and biomedical applications – A comprehensive review DOI
Mohamed T. El‐Saadony, Ahmed M. Saad, Samar Sami Alkafaas

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142832 - 142832

Published: April 1, 2025

Language: Английский

Citations

0

Biomass-derived green polymers for environmental remediation DOI
Akbar Hojjati‐Najafabadi, Reza Behmadi, Peizhong Feng

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 213 - 265

Published: Jan. 1, 2025

Language: Английский

Citations

0