Biosensor with Microchannel for Broadband Dielectric Characterization of Nanoliter Cell Suspensions up to 110 GHz DOI Creative Commons
Wen Sun, Jianhua Wang,

Jin Chen

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(7), P. 327 - 327

Published: June 30, 2024

Cell dielectric property measurement holds significant potential for application in cell detection and diagnosis due to its label-free noninvasive nature. In this study, we developed a biosensor designed measure the permittivity of liquid samples, particularly suspensions at nanoliter scale, utilizing microwave millimeter wave coplanar waveguides conjunction with microchannel. This facilitates scattering parameters within frequency domain ranging from 1 GHz 110 GHz. The obtained are then converted into constants using specific algorithms. A capture structure microchannel ensures that remain stable zone. feasibility was confirmed by comparison commercial Keysight probe. We measured three different (HepG2, A549, MCF-7) our biosensor. also counted number cells captured multiple measurements each type compared corresponding changes permittivity. results indicated real part HepG2 is 0.2–0.8 lower than other two types. difference between A549 MCF-7 relatively minor, only 0.2–0.4. fluctuations spectrum caused numbers during were smaller differences observed Thus, sensor suitable measuring can be utilized label-free, studies identifying biological suspensions.

Language: Английский

Recent Advances in Conductive Polymers-Based Electrochemical Sensors for Biomedical and Environmental Applications DOI Open Access

Youheng Pan,

Jing Zhang, Xin Guo

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(11), P. 1597 - 1597

Published: June 4, 2024

Electrochemical sensors play a pivotal role in various fields, such as biomedicine and environmental detection, due to their exceptional sensitivity, selectivity, stability, rapid response time, user-friendly operation, ease of miniaturization integration. In addition the research conducted application field, significant focus is placed on selection optimization electrode interface materials for electrochemical sensors. The detection performance these can be significantly enhanced by modifying either inorganic metal electrodes or printed electrodes. Among numerous available modification materials, conductive polymers (CPs) possess not only excellent conductivity exhibited conductors but also unique three-dimensional structural characteristics inherent polymers. This distinctive combination allows CPs increase active sites during process while providing channels ion transmission facilitating efficient electron transfer reaction processes. review article primarily highlights recent progress concerning an ideal choice owing remarkable features that make them well-suited biomedical applications.

Language: Английский

Citations

13
Advanced detection of the protozoacide dimetridazole in complex fluids using cassiterite nanoparticles incorporated carbon black composite DOI
Chandini Ragumoorthy, Nandini Nataraj,

Tse-Wei Chen

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 470, P. 142660 - 142660

Published: Dec. 26, 2024

Language: Английский

Citations

4
Graphene, graphene oxide or modified graphene in polyaniline based nanocomposites—features and technical highlights DOI
Ayesha Kausar

Journal of Thermoplastic Composite Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 11, 2024

Polyaniline is a remarkable conjugated polymer having valuable structural and physical characteristics. Nevertheless, polyaniline has poor solubility durability which had limited its practical utilization. Consequently, been reinforced with carbonaceous inorganic nanoparticles to enhance processability properties, such as electrical/thermal conductivity thermal/mechanical stability. Accordingly, applied matrix material form nanocomposites graphene one atom thick nanosheet of hexagonally arranged carbon atoms. Subsequently, well modified forms have utilized important nanoadditives for the matrix. This state-of-the-art review article designed investigate fabrication, characteristics, applications graphene/modified based nanomaterials. Potential enhancements in characteristics pristine upon reinforcement seemed be reliant matrix-nanofiller interactions, interface formation, synergetic effects between polyaniline-graphene. aspects polyaniline/graphene discussed regarding their fields solar cells, supercapacitors, sensors. According literature analysis, dye sensitized cell on oxide exhibited superior power conversion efficiencies ∼2.0-7.6 % open circuit voltage ∼500-800 mV. Supercapacitor electrodes polyaniline/reduced showed significantly high values specific capacitance retention ∼1100-1900 Fg −1 ∼80-98 %, respectively, during >5000-6000 cycles. Besides, depicted sensitivity response time gas sensors (∼20 50 s, respectively) humidity (>90 4-7 low detection limits biosensors.

Language: Английский

Citations

2
Nature-inspired protein mineralization strategies for nanoparticle construction: advancing effective cancer therapy DOI
Yuan Cao,

Rui Xu,

Yixia Liang

et al.

Nanoscale, Journal Year: 2024, Volume and Issue: 16(29), P. 13718 - 13754

Published: Jan. 1, 2024

The biomimetic mineralization strategy based on natural proteins and metal ions provides an effective method for constructing nanoparticles. By regulating the proportion of ingredients, precise control assembly nanoparticles can be achieved.

Language: Английский

Citations

1
Biosensor with Microchannel for Broadband Dielectric Characterization of Nanoliter Cell Suspensions up to 110 GHz DOI Creative Commons
Wen Sun, Jianhua Wang,

Jin Chen

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(7), P. 327 - 327

Published: June 30, 2024

Cell dielectric property measurement holds significant potential for application in cell detection and diagnosis due to its label-free noninvasive nature. In this study, we developed a biosensor designed measure the permittivity of liquid samples, particularly suspensions at nanoliter scale, utilizing microwave millimeter wave coplanar waveguides conjunction with microchannel. This facilitates scattering parameters within frequency domain ranging from 1 GHz 110 GHz. The obtained are then converted into constants using specific algorithms. A capture structure microchannel ensures that remain stable zone. feasibility was confirmed by comparison commercial Keysight probe. We measured three different (HepG2, A549, MCF-7) our biosensor. also counted number cells captured multiple measurements each type compared corresponding changes permittivity. results indicated real part HepG2 is 0.2–0.8 lower than other two types. difference between A549 MCF-7 relatively minor, only 0.2–0.4. fluctuations spectrum caused numbers during were smaller differences observed Thus, sensor suitable measuring can be utilized label-free, studies identifying biological suspensions.

Language: Английский

Citations

0