The Principle and Practical Progress of 3D Printing Technology in Knee Joint and Meniscus DOI Creative Commons
Zelin Liu, Xiaohan Yang

Highlights in Science Engineering and Technology, Journal Year: 2024, Volume and Issue: 123, P. 463 - 472

Published: Dec. 24, 2024

Repairing meniscus tears poses significant challenges, impacting normal knee joint movement and potentially leading to secondary osteoarthritis over time. The limited availability of donor tissue, coupled with issues such as graft rejection, results in an inadequate supply for tissue replacement regeneration patients. This context has led the development regenerative scaffolds. Advances 3D printing technology cartilage have enabled creation intricate scaffolds high precision biological activity. These effectively mimic extracellular matrix (ECM) cartilage, ultimately facilitating by providing structural support promoting cell attachment, proliferation, differentiation. paper primarily discusses applications printed engineering medicine, introducing comparing various examples technologies raw materials. Additionally, we examine performance requirements scaffolds, address existing challenges limitations, consider prospects this field.

Language: Английский

Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges DOI Creative Commons
Vidhi Mathur, Prachi P. Agarwal, Meghana Kasturi

et al.

Journal of Tissue Engineering, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 1, 2025

The field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial role in enabling the fabrication complex tissue constructs. This review explores innovative that are currently shaping future 3D bioprinting, focusing on their composition, functionality, and potential for engineering, drug delivery, regenerative medicine. development bioinks, incorporating natural synthetic materials, offers unprecedented opportunities personalized However, rapid technological progress raises regulatory challenges regarding safety, standardization, long-term biocompatibility. paper addresses these challenges, examining current frameworks need updated guidelines to ensure patient safety product efficacy. By highlighting both hurdles, this comprehensive overview landscape emphasizing necessity cross-disciplinary collaboration between scientists, clinicians, bodies achieve successful clinical applications.

Language: Английский

Citations

4

Biomaterials Adapted to Vat Photopolymerization in 3D Printing: Characteristics and Medical Applications DOI Creative Commons
Iosif-Aliodor Timofticiuc, Octavian Călinescu, Adrian Iftime

et al.

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 15(1), P. 7 - 7

Published: Dec. 22, 2023

Along with the rapid and extensive advancements in 3D printing field, a diverse range of uses for have appeared spectrum medical applications. Vat photopolymerization (VPP) stands out as one most extensively researched methods printing, its main advantages being high speed ability to produce high-resolution structures. A major challenge using VPP 3D-printed materials medicine is general incompatibility standard resin mixtures requirements biocompatibility biofunctionality. Instead developing completely new materials, an alternate approach solving this problem involves adapting existing biomaterials. These are incompatible their pure form but can be adapted chemistry process through use innovative addition specific pre- post-printing steps. This review's primary objective highlight biofunctional biocompatible that been VPP. We present compare suitability these different applications propose other biomaterials could further order fulfill patient-specific requirements.

Language: Английский

Citations

24

Investigating the Characteristics of Nano-Graphite Composites Additively Manufactured Using Stereolithography DOI Open Access
Ariyana Dwiputra Nugraha, Vishnu Vijay Kumar, Jessie Puteri Gautama

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(8), P. 1021 - 1021

Published: April 9, 2024

Stereolithography has emerged as a recent method in fabricating complex structures with high accuracy. Components using resin have poorer properties. The current study investigates the improvement properties of nano-graphite composites fabricated by SLA technique. are compared for plain and 0.2%, 0.5%, 1%, 3%, 5% (w/v) mixed UV-curable resin. Various analyses were conducted, including viscosity, UV spectroscopy, moisture content, water absorption, gel tensile, bending, hardness testing, microscopic characterization. results from experiments showed difference each percentage specimen tested, such property, which shows that greater added (5%), opaquer will appear less light be reflected. Viscosity testing to resin, viscosity. spectroscopy produced information about electronic structure molecules, their composition, purity, concentration. Observations content analysis found specimens higher percentages affected physical mechanical properties, leading easier warping, cracking, decreased strength, etc. Tensile bending added, effect on fracture. However, certain tests did not consistently yield significant variations among when different particularly evident chemical resistance testing. This offers valuable insights into application via method.

Language: Английский

Citations

9

Advancing plant science through precision 3D bioprinting: new tools for research and biotech applications DOI
Imani Madison, Miguel Á. Moreno-Risueno, Rosangela Sozzani

et al.

Current Opinion in Biotechnology, Journal Year: 2025, Volume and Issue: 91, P. 103250 - 103250

Published: Jan. 8, 2025

Language: Английский

Citations

1

3D bioprinting: Advancing the future of food production layer by layer DOI Creative Commons

Nisansala Chandimali,

Seon-Gyeong Bak,

Eun Hyun Park

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 471, P. 142828 - 142828

Published: Jan. 9, 2025

Language: Английский

Citations

1

Mucin-Based Dual Cross-Linkable IPN Hydrogel Bioink for 3D Bioprinting and Cartilage Tissue Engineering DOI

Sruthi C. Sasikumar,

Upashi Goswami, Ashok M. Raichur

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

The cartilage possesses limited regenerative capacity, necessitating advanced approaches for its repair. This study introduces a bioink designed tissue engineering (TE) by incorporating ionically cross-linkable alginate into the photo-cross-linkable MuMA bioink, resulting in double cross-linked interpenetrating network (IPN) hydrogel. Additionally, hyaluronic acid (HA), natural component of and synovial fluid, was added to enhance scaffold's properties. HA has been demonstrated improve lubrication, regulate inflammation, promote cell proliferation, support extracellular matrix (ECM) deposition regeneration, making it valuable TE. Comprehensive experiments were conducted assess morphology, swelling, degradation, mechanical rheological properties, printability, biocompatibility. Results indicated that scaffolds comprising MuMA, alginate, exhibited compressive moduli comparable native cartilage, unlike single variants. cross-linking also influenced water uptake, porosity, contributing scaffold durability stability chondrocyte support. Biocompatibility tests with C28/I2 cells cell-supportive chondrogenic potential bioink. establishes mucin as versatile material specialized applications.

Language: Английский

Citations

1

Recent Developments in Bio-Ink Formulations Using Marine-Derived Biomaterials for Three-Dimensional (3D) Bioprinting DOI Creative Commons
Zied Khiari

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(3), P. 134 - 134

Published: March 16, 2024

3D bioprinting is a disruptive, computer-aided, and additive manufacturing technology that allows the obtention, layer-by-layer, of complex structures. This believed to offer tremendous opportunities in several fields including biomedical, pharmaceutical, food industries. Several processes bio-ink materials have emerged recently. However, there still pressing need develop low-cost sustainable with superior qualities (excellent mechanical, viscoelastic thermal properties, biocompatibility, biodegradability). Marine-derived biomaterials, polysaccharides proteins, represent viable renewable source for formulations. Therefore, focus this review centers around use marine-derived biomaterials formulations bio-ink. It starts general overview followed by description most commonly used bioprinting, special attention paid chitosan, glycosaminoglycans, alginate, carrageenan, collagen, gelatin. The challenges facing application within biomedical pharmaceutical along future directions are also discussed.

Language: Английский

Citations

6

A review of the current state of the art in gelatin methacryloyl-based printing inks in bone tissue engineering DOI Creative Commons

Mihaela-Raluca Dobrișan,

Adriana Lungu, Mariana Ioniţă

et al.

Virtual and Physical Prototyping, Journal Year: 2024, Volume and Issue: 19(1)

Published: July 22, 2024

Achieving efficient scaffolds for bone tissue engineering (TE) requires smartly defined parameters reaching a balance between physical–chemical properties, biocompatibility and complex architectures. Three-dimensional (3D) printing offers precise geometry control of the desired scaffold at micro-scale. However, performance 3D is highly dependent on formulation, challenge being to achieve suitable ink establish most parameters. Gelatin methacryloyl (GelMA) emerges as promising due superior biological photocrosslinking ability printability. The present review focuses evolution GelMA-based inks bioinks from simplest advanced multicomponent formulations capable regeneration. Additionally, comparative analysis different photoinitiators covered, indicating each one's advantages disadvantages. Furthermore, main bioprinting methods that are used in GelMA outlined with required their influence final product performance.

Language: Английский

Citations

4

Perspectives of Additive Manufacturing in 5.0 Industry DOI Open Access
Dariusz Sala, M. Richert

Materials, Journal Year: 2025, Volume and Issue: 18(2), P. 429 - 429

Published: Jan. 17, 2025

Additive manufacturing is a technology that creates objects by adding successive layers of material. The 3D method an alternative to subtractive production, in which production involves removing material from the initial solid. printing requires design manufactured object using computer design, for example, one following programs: CAD, 3DCrafter, Wings 3D, Cinema 3, Blender, 3ds Max, Autodesk Inventor, and others. It also possible scan existing be technology. An important element Industry 5.0 technology, due its favorable environmental orientation flexibility. Three-dimensional uses recycled materials such as powders. Therefore, it can part circular economy, contributing protection. not only complements technologies enabling rapid prototyping but plays fundamental role sectors dentistry medicine. This article consists seven chapters relating various aspects context assumptions challenges 5.0. examines impact recycling potential illustrates economic integration this within industries, discusses future development prospects.

Language: Английский

Citations

0

Modeling of Extrusion 3D Bioprinting Precision Considering the Non-Newtonian Rheological Dynamics of Gelatin-Chitosan Hydrogels DOI
Bowen Li, Chuanzhen Huang, Zhen Wang

et al.

ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Language: Английский

Citations

0