International Journal of Polymeric Materials,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 33
Published: Dec. 16, 2024
This
review
delves
into
the
efficacy
of
electrospun
nanofibers
as
structures
capable
neutralizing
Reactive
Oxygen
Species
(ROS),
thereby
aiding
in
acceleration
wound
repair.
ROS
occupy
a
dual
position
cellular
dynamics,
being
indispensable
for
intracellular
communication,
yet
they
potentially
exacerbate
oxidative
stress
which
can
stall
healing
trajectory.
The
method
electrospinning
synthesizes
distinguished
by
their
expansive
surface
area
relative
to
volume
and
notable
porosity,
rendering
them
optimally
suited
medical
endeavors,
particularly
frameworks
that
bolster
recuperation.
analysis
elucidates
diverse
roles
these
play,
from
enhancing
clot
formation
combating
microbial
invasion
mitigating
inflammation,
fostering
proliferation,
facilitating
angiogenesis—each
pivotal
component
effective
mending
wounds.
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
unknown, P. 140064 - 140064
Published: Jan. 1, 2025
Curcumin,
a
hydrophobic
drug
derived
from
the
rhizome
of
Curcuma
longa,
exhibits
significant
bioactive
properties,
including
antioxidant
and
antimicrobial
potential.
However,
its
poor
water
solubility
rapid
degradation
limit
practical
applications.
This
study
presents
novel
design
electrospun
nanofibers
using
Curcumin/hydroxypropyl-β-cyclodextrin
inclusion
complex
(HP-β-CD-IC)
combined
with
pullulan
to
enhance
thermal
stability
controlled
release.
In
uniaxial
nanofibers,
curcumin/HP-β-CD-IC
is
uniformly
distributed,
whereas
in
coaxial
serves
as
core
material,
wall
material.
X-ray
diffraction
Fourier-transform
infrared
spectroscopy
confirmed
successful
formation,
fibers
showing
no
crystalline
peaks
curcumin.
Differential
scanning
calorimetry
indicated
enhanced
stability,
melting
points
shifting
279.19
°C
291.63
for
fibers,
respectively.
Scanning
electron
microscopy
transmission
verified
core-shell
structure
uniform
morphology.
vitro
release
studies
revealed
that
achieved
higher
cumulative
(93
±
1.41
%)
compared
(80
2.82
over
350
min.
Antibacterial
tests
demonstrated
improved
activity
against
S.
aureus
E.
coli.
Addressing
critical
need
stable
bioavailable
delivery
compounds,
this
innovative
nanofiber
holds
great
promise
revolutionizing
applications
food
technology
delivery.
Macromolecular Rapid Communications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 20, 2025
Abstract
There
is
intense
research
during
the
past
few
decades
to
design
and
fabricate
drug
delivery
systems
using
electrospinning
system.
Electrospinning
an
efficient
technique
produce
nanofiber
materials
with
different
dimensions
morphologies
by
adjusting
processing
parameters.
becoming
innovative
technology
that
promotes
pursuit
maintenance
of
human
health.
Herein,
review
discusses
contribution
in
systems,
summarising
modification
various
system
configurations
effects
process
parameters
on
fibers,
their
application
including
carrier
materials,
loaded
drugs
release
mechanisms
illustrates
medical
applications.
Finally,
this
challenges,
bottlenecks,
development
prospects
field
terms
scaling
up
for
clinical
use
exploring
potential
solutions
pave
way
establish
future
systems.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
13
Published: March 6, 2025
In
the
field
of
wound
treatment,
chronic
wounds
pose
a
significant
burden
on
medical
system,
affecting
millions
patients
annually.
Current
treatment
methods
often
fall
short
in
promoting
effective
healing,
highlighting
need
for
innovative
approaches.
Electrospinning,
technique
that
has
garnered
increasing
attention
recent
years,
shows
promise
care
due
to
its
unique
characteristics
and
advantages.
Recent
studies
have
explored
use
electrospun
nanofibers
demonstrating
their
efficacy
cell
growth
tissue
regeneration.
Researchers
investigated
various
materials
electrospinning,
including
polymers,
ceramics,
carbon
nanotubes
(CNTs),
metals.
Hydrogel,
as
biomaterial
been
widely
studied
matrix.
When
combined
with
it
can
be
used
develop
dressings
multiple
functions.
This
article
is
review
application
electrospinning
technology
treatment.
It
introduces
current
research
status
areas
pathophysiology,
preparation
technology,
dressing
development,
hoping
provide
references
directions
future
research.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: April 9, 2025
In
this
review,
we
explore
the
exciting
potential
of
nanodiamonds
(NDs)
as
innovative
materials
for
future
wound
dressings.
These
aim
to
tackle
important
issues
in
care
and
offer
fresh
solutions.
While
NDs
show
promising
mechanical
structural
properties,
their
full
healing
applications
is
still
not
fully
explored.
We
emphasize
unique
features-like
high
surface
area,
dispersion
functional
groups,
excellent
purity-which
contribute
stability,
adhesion,
growth,
movement-all
critical
effective
tissue
repair.
also
focused
on
modifying
these
particles
using
various
functionalization,
which
can
enhance
biocompatibility,
antibacterial
heat
conductivity,
wettability.
This
positions
a
powerful
tool
improving
chronic
future.
However,
there
are
notable
challenges
when
it
comes
scaling
up
ND-based
nanofiber
matrices,
currently
limits
electrospinning
process
mass
production.
Also,
with
physical
chemical
stability
nanofibers
interacting
cells
need
be
resolved
guarantee
long-lasting
effectiveness.
study,
by
suggesting
solutions
like
optimizing
process,
creating
hybrid
scaffolds.
Our
findings
that
innovations
effectively
address
scalability
issues,
paving
way
broader
clinical
applications.
review
only
emphasizes
advantages
but
introduces
new
insights
enhancing
biocompatibility
functionality
nanofibers,
finally
pushing
technology
dressings
forward.
Materials,
Journal Year:
2024,
Volume and Issue:
17(21), P. 5379 - 5379
Published: Nov. 4, 2024
The
preparation
of
core–sheath
fibers
by
electrospinning
is
a
topic
significant
interest
for
producing
composite
with
distinct
core
and
sheath
functionalities.
Moreover,
in
fibers,
low-molecular-weight
substances
or
nanosized
inorganic
additives
can
be
deposited
targeted
manner
within
the
sheath.
Commonly,
obtaining
structure,
coaxial
used.
It
requires
spinneret
suitable
immiscible
solvents
inner
outer
solutions.
single-nozzle
emulsions
address
these
issues,
but
use
stabilizing
agent
needed.
A
third
approach—preparation
homogeneous
blend
solutions
two
polymers
polymer/low-molecular-weight
substance—has
been
much
less
studied.
circumvents
difficulties
associated
emulsion
thoroughly
discussed
this
review.
formation
case
attributed
to
phase-separation-driven
self-organization
during
process.
Some
possibilities
core–double
using
same
method
are
also
indicated.
gained
knowledge
on
potential
applications
prepared
discussed.
