Analytical Chemistry,
Journal Year:
2019,
Volume and Issue:
91(16), P. 10448 - 10457
Published: June 13, 2019
Developing
easy-to-use
and
miniaturized
detectors
is
essential
for
in-field
monitoring
of
environmentally
hazardous
substances,
such
as
the
cyanotoxins.
We
demonstrated
a
differential
fluorescent
sensor
array
made
aptamers
single-stranded
DNA
(ssDNA)
dyes
multiplexed
detection
discrimination
four
common
cyanotoxins
with
an
ordinary
smartphone
within
5
min
reaction.
The
assay
reagents
were
preloaded
dried
in
microfluidic
chip
long
shelf
life
over
60
days.
Upon
addition
analyte
solutions,
competitive
binding
cyanotoxin
to
specific
aptamer-dye
conjugate
occurred.
A
zone-specific
concentration-dependent
reduction
green
fluorescence
was
observed
result
aptamer
conformation
change.
aptasensors
are
fully
optimized
by
quantification
their
dissociation
constants,
tuning
stoichiometric
ratios
reaction
mixtures,
implementation
internal
intensity
correction
step.
allowed
accurate
identification
measurement
important
cyanotoxins,
including
anatoxin-a
(ATX),
cylindrospermopsin
(CYN),
nodularin
(NOD),
microcystin-LR
(MC-LR),
parallel,
limit
(LOD)
down
few
nanomolar
(<3
nM),
which
close
World
Health
Organization's
guideline
maximum
concentration
drinking
water.
smartphone-based
platform
also
showed
remarkable
chemical
specificity
against
potential
interfering
agents
performance
system
tested
validated
real
lake
water
samples
that
contaminated
trace
levels
individual
well
binary,
ternary,
quaternary
mixtures.
Finally,
app
interface
has
been
developed
rapid
on-site
data
processing
display.
Materials,
Journal Year:
2019,
Volume and Issue:
12(1), P. 121 - 121
Published: Jan. 2, 2019
Enzyme-based
biosensing
devices
have
been
extensively
developed
over
the
last
few
decades,
and
proven
to
be
innovative
techniques
in
qualitative
quantitative
analysis
of
a
variety
target
substrates
wide
range
applications.
Distinct
advantages
that
enzyme-based
biosensors
provide,
such
as
high
sensitivity
specificity,
portability,
cost-effectiveness,
possibilities
for
miniaturization
point-of-care
diagnostic
testing
make
them
more
attractive
research
focused
on
clinical
analysis,
food
safety
control,
or
disease
monitoring
purposes.
Therefore,
this
review
article
investigates
operating
principle
enzymatic
utilizing
electrochemical,
optical,
thermistor,
piezoelectric
measurement
their
applications
literature,
well
approaches
improving
use
enzymes
biosensors.
Marine Drugs,
Journal Year:
2018,
Volume and Issue:
16(2), P. 65 - 65
Published: Feb. 19, 2018
In
recent
decades,
environmental
pollution
has
emerged
as
a
core
issue,
around
the
globe,
rendering
it
of
fundamental
concern
to
eco-toxicologists,
biologists,
eco-chemists,
pathologists,
and
researchers
from
other
fields.
The
dissolution
polluting
agents
is
leading
cause
all
key
spheres
including
hydrosphere,
lithosphere,
biosphere,
among
others.
widespread
occurrence
various
pollutants
toxic
heavy
metals
emerging
hazardous
contaminants
serious
concern.
With
increasing
scientific
knowledge,
socioeconomic
awareness,
human
health
problems,
ecological
apprehensions,
people
are
more
concerned
about
adverse
outcomes.
Against
this
background,
several
removal
methods
have
been
proposed
implemented
with
aim
addressing
sustainable
eco-friendly
development.
Among
them,
biosorption
using
naturally
inspired
sources,
e.g.,
marine
algae,
considerable
advantages.
past
few
years,
algae
extensively
studied
due
their
natural
origin,
overall
cost-effective
ratio,
effectiveness
against
broader
pollutant
range;
thus,
they
considered
potential
alternative
conventional
used
for
decontamination.
Herein,
an
effort
made
highlight
importance
biosorbents
role
in
biosorption.
Biosorption
mechanisms
factors
affecting
activities
also
discussed
review.
utilization
biosorbent
numerous
potentially
elements
reviewed.
Chemical Reviews,
Journal Year:
2020,
Volume and Issue:
120(23), P. 12903 - 12993
Published: Oct. 14, 2020
Bioelectrocatalysis
is
an
interdisciplinary
research
field
combining
biocatalysis
and
electrocatalysis
via
the
utilization
of
materials
derived
from
biological
systems
as
catalysts
to
catalyze
redox
reactions
occurring
at
electrode.
synergistically
couples
merits
both
electrocatalysis.
The
advantages
include
high
activity,
selectivity,
wide
substrate
scope,
mild
reaction
conditions.
possible
renewable
electricity
electron
source
energy
conversion
efficiency.
These
properties
are
integrated
achieve
selective
biosensing,
efficient
conversion,
production
diverse
products.
This
review
seeks
systematically
comprehensively
detail
fundamentals,
analyze
existing
problems,
summarize
development
status
applications,
look
toward
future
directions
bioelectrocatalysis.
First,
structure,
function,
modification
bioelectrocatalysts
discussed.
Second,
essentials
bioelectrocatalytic
systems,
including
transfer
mechanisms,
electrode
materials,
medium,
described.
Third,
application
bioelectrocatalysis
in
fields
biosensors,
fuel
cells,
solar
catalytic
mechanism
studies,
bioelectrosyntheses
high-value
chemicals
summarized.
Finally,
developments
a
perspective
on
suggested.
Nanoscale,
Journal Year:
2020,
Volume and Issue:
13(2), P. 553 - 580
Published: Dec. 9, 2020
The
growing
demand
for
reliable
and
robust
methodology
in
bio-chemical
sensing
calls
the
continuous
advancement
of
sensor
technologies.
Over
last
two
decades,
surface-enhanced
Raman
spectroscopy
(SERS)
has
emerged
as
one
most
promising
analytical
techniques
sensitive
trace
analysis
or
detection
biomedical
agri-food
applications.
SERS
overcomes
inherent
sensitivity
limitation
associated
with
spectroscopy,
which
provides
vibrational
"fingerprint"
spectra
molecules
that
makes
it
unique
versatile
among
other
techniques.
This
paper
comprehensively
reviews
recent
advancements
biomedical,
food
agricultural
applications
over
6
years,
we
envision
that,
near
future,
some
these
platforms
have
potential
to
be
translated
a
point-of-care
rapid
real-life
end-user
merits
limitations
various
designs
are
analysed
discussed
based
on
critical
features
such
sensitivity,
specificity,
usability,
repeatability
reproducibility.
We
conclude
by
highlighting
opportunities
challenges
field
while
stressing
technological
gaps
addressed
realizing
commercially
viable
sensors
practical
ACS ES&T Water,
Journal Year:
2021,
Volume and Issue:
1(3), P. 462 - 478
Published: Feb. 15, 2021
The
release
of
chemicals
into
water
systems
has
resulted
in
pollution
many
parts
the
world,
threatening
human
health
and
aquatic
ecosystems.
Sources
chemical
discharge
include
industry,
agricultural,
wastewater
treatment
plants,
stormwater
overflows.
To
combat
pollution,
European
Union
introduced
several
directives
that
set
concentration
limits
for
drinking
water,
surface
groundwater.
meet
these
limits,
it
is
essential
rapid,
reliable,
sensitive
analytical
detection
be
developed
put
use.
This
Review
presents
progress
made
development
electrochemical
biosensors
environmental
toxicants
(pesticides
heavy
metals)
over
past
seven
years
(2014–2020).
For
those
unfamiliar
with
this
field
research,
concept
a
biosensor
followed
by
critical
evaluation
their
performance
detecting
toxicants.
Current
challenges
are
discussed
as
well
potential
avenues
future
including
demands
enhanced
performance,
improved
stability
shelf
life,
greater
integration
microfluidic
devices
wireless
database
technologies
remote
sensing
applications.
We
believe
will
beneficial
enhance
awareness
appreciation
role
can
play
protecting
our
environment
resources.
Environment International,
Journal Year:
2022,
Volume and Issue:
166, P. 107357 - 107357
Published: June 18, 2022
Conventional
techniques
(e.g.,
culture-based
method)
for
bacterial
detection
typically
require
a
central
laboratory
and
well-trained
technicians,
which
may
take
several
hours
or
days.
However,
recent
developments
within
various
disciplines
of
science
engineering
have
led
to
major
paradigm
shift
in
how
microorganisms
can
be
detected.
The
analytical
sensors
are
widely
used
medical
applications
the
literature
being
extended
rapid
on-site
monitoring
pathogens
food,
water
environment.
Especially,
low-resource
settings
such
as
low
middle-income
countries,
due
advantages
cost,
rapidness
potential
field-testing,
their
use
is
indispensable
sustainable
development
regions.
Within
this
context,
paper
discusses
methods
biosensors
ensure
food
safety,
quality
environmental
monitoring.
In
brief,
most
our
discussion
focused
on
including
microfluidic
chips.
performances
sensitivity,
specificity
usability
these
sensors,
well
brief
comparison
with
conventional
bacteria
detection,
form
core
part
discussion.
Furthermore,
we
provide
holistic
viewpoint
future
research
should
focus
exploring
synergy
different
sensing
technologies
by
developing
an
integrated
multiplexed,
sensitive
accurate
that
will
enable
The Analyst,
Journal Year:
2019,
Volume and Issue:
145(2), P. 364 - 384
Published: Dec. 12, 2019
Plasmonics
has
drawn
significant
attention
in
the
area
of
biosensors
for
decades
due
to
unique
optical
properties
plasmonic
resonant
nanostructures.
While
sensitivity
and
specificity
molecular
detection
relies
significantly
on
resonance
conditions,
been
dedicated
design,
fabrication,
optimization
substrates.
The
adequate
choice
materials,
structures,
functionality
goes
hand
with
a
fundamental
understanding
plasmonics
enable
development
practical
that
can
be
deployed
real
life
situations.
Here
we
provide
brief
review
detailing
most
recent
developments
applications.
Besides
metals,
novel
materials
such
as
graphene
are
highlighted.
Sensors
based
Surface
Plasmon
Resonance
(SPR),
Localized
(LSPR),
Enhanced
Raman
Spectroscopy
(SERS)
presented
classified
their
structure.
In
addition,
applications
environment
monitoring,
health
diagnosis,
food
safety
presented.
Potential
problems
related
implementation
discussed
an
outlook
is
Sensors,
Journal Year:
2022,
Volume and Issue:
22(4), P. 1513 - 1513
Published: Feb. 15, 2022
The
monitoring
of
environmental
pollution
requires
fast,
reliable,
cost-effective
and
small
devices.
This
need
explains
the
recent
trends
in
development
biosensing
devices
for
pollutant
detection.
present
review
aims
to
summarize
newest
regarding
use
biosensors
detect
contaminants.
Enzyme,
whole
cell,
antibody,
aptamer,
DNA-based
biomimetic
sensors
are
discussed.
We
their
applicability
detection
various
pollutants
mention
constructive
characteristics.
Several
principles
used
biosensor
design:
amperometry,
conductometry,
luminescence,
etc.
They
differ
terms
rapidity,
sensitivity,
profitability,
design.
Each
one
is
characterized
by
specific
selectivity
limits
depending
on
sensitive
element.
Mimetic
slowly
gaining
attention
from
researchers
users
due
advantages
compared
with
classical
ones.
Further
studies
necessary
robust
that
can
successfully
be
complex
matrices
without
prior
sample
preparation.