Biofilm Formation, and Related Impacts on Healthcare, Food Processing and Packaging, Industrial Manufacturing, Marine Industries, and Sanitation–A Review

Applied Microbiology, Journal Year: 2023, Volume and Issue: 3(3), P. 629 - 665

Published: June 26, 2023

Biofilm formation can lead to problems in healthcare, water distribution systems, food processing and packaging, industrial manufacturing, marine industries, sanitation. These microbial communities proliferate on biotic or abiotic surfaces, are responsible for human disease decreasing production efficiency service equipment life many fields. The of biofilm starts with the attachment bacteria surface, followed by bacterial proliferation maturation community. After forming a biofilm, not resistant antimicrobial agents their planktonic forms turn resistant. antibiotic resistance association biofilms generating infectious diseases humans, highlight need designing novel successful antibacterial, anti-biofilm, anti-infection materials. This paper aims review mechanism formation, impact different interaction nanoparticles bacteria, strategies design anti-biofilm Examples bio-implants, coatings, medical devices, wound dressings, sutures reviewed.

Language: Английский

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CRISPR/Cas12a-based biosensors for environmental monitoring and diagnostics

Environmental Technology & Innovation, Journal Year: 2024, Volume and Issue: 34, P. 103625 - 103625

Published: April 4, 2024

Contaminants, such as nucleic acids or toxic small molecules, threaten both human health and ecosystems when they infiltrate the environment. The precise highly sensitive identification of contaminants holds paramount importance across diverse domains, including safeguarding food integrity, facilitating clinical diagnostics, monitoring environmental conditions. Traditional methodologies, encompassing spectroscopy, chromatography, sequencing, metagenomics, have conventionally served pivotal roles in detection processes. Nevertheless, these methods encountered recurring challenges related to sensitivity, specificity, portability. This review focuses on groundbreaking CRISPR/Cas12-based biosensors. These biosensors leverage incredible precision programmability CRISPR/Cas system recognize specific targets. Here, we comprehensively assess fundamental mechanisms that enable detection, ranging from guide RNA design collateral cleavage. versatility CRISPR/Cas12 becomes evident through their applications. applications encompass medical safety, monitoring. transition conventional ultimately represents a significant milestone contaminant detection. By incorporating molecular biology, nanotechnology, bioinformatics, potential reshape landscape water CRIPSR-Cas diagnostics is transformative technology paves way for safer healthier future environment life.

Language: Английский

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Viral outbreaks detection and surveillance using wastewater-based epidemiology, viral air sampling, and machine learning techniques: A comprehensive review and outlook

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 803, P. 149834 - 149834

Published: Aug. 21, 2021

Language: Английский

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Gold nanoparticle based biosensors for rapid pathogen detection: A review

Environmental Nanotechnology Monitoring & Management, Journal Year: 2022, Volume and Issue: 18, P. 100756 - 100756

Published: Nov. 12, 2022

Language: Английский

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Terahertz thermal curve analysis for label-free identification of pathogens

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: June 16, 2022

In this study, we perform a thermal curve analysis with terahertz (THz) metamaterials to develop label-free identification tool for pathogens such as bacteria and yeasts. The resonant frequency of the metasensor coated bacterial layer changes function temperature; provides unique fingerprint specific individual microbial species without use fluorescent dyes antibodies. Differential curves obtained from temperature-dependent resonance exhibit peaks consistent phases, growth, inactivation, DNA denaturation, cell wall destruction. addition, can distinguish gram-negative gram-positive which show strong in temperature range Finally, THz melting on mixture pathogenic are successfully distinguished each other, is essential practical clinical environmental applications blood culture.

Language: Английский

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Synergizing Nanomaterials and Artificial Intelligence in Advanced Optical Biosensors for Precision Antimicrobial Resistance Diagnosis

ACS Synthetic Biology, Journal Year: 2024, Volume and Issue: 13(6), P. 1600 - 1620

Published: June 6, 2024

Antimicrobial resistance (AMR) poses a critical global One Health concern, ensuing from unintentional and continuous exposure to antibiotics, as well challenges in accurate contagion diagnostics. Addressing AMR requires strategic approach that emphasizes early stage prevention through screening clinical, environmental, farming, livestock settings identify nonvulnerable antimicrobial agents the associated genes. Conventional diagnostics, like antibiotic susceptibility testing, possess drawbacks, including high costs, time-consuming processes, significant manpower requirements, underscoring need for intelligent, prompt, on-site diagnostic techniques. Nanoenabled artificial intelligence (AI)-supported smart optical biosensors present potential solution by facilitating rapid point-of-care detection with real-time, sensitive, portable capabilities. This Review comprehensively explores various types of nanobiosensors, such surface plasmon resonance sensors, whispering-gallery mode coherence tomography, interference reflection imaging surface-enhanced Raman spectroscopy, fluorescence microring tweezer biosensors, By harnessing unique advantages these nanoenabled revolutionary paradigm shift diagnostics can be achieved, characterized results, sensitivity, portability, integration Internet-of-Things (IoT) technologies. Moreover, enable personalized monitoring detection, significantly reducing turnaround time eliminating human resources needed sample preservation transportation. Their holistic environmental surveillance further enhances capabilities diverse settings, leading improved modern-age healthcare practices more effective management treatments. Embracing advanced tools promises bolster capacity combat safeguard Health.

Language: Английский

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Advanced technologies towards improved HPV diagnostics

Journal of Medical Virology, Journal Year: 2024, Volume and Issue: 96(2)

Published: Jan. 31, 2024

Abstract Persistent infection with high‐risk types of human papillomaviruses (HPV) is a major cause cervical cancer, and an important factor in other malignancies, for example, head neck cancer. Despite recent progress screening vaccination, the incidence mortality are still relatively high, especially low‐income countries. The financial burden associated treatment could be decreased if simple, rapid, inexpensive technology HPV testing becomes available, targeting individuals further monitoring increased risk developing Commercial tests available market often expensive, time‐consuming, require sophisticated instrumentation, which limits their more widespread utilization. To address these challenges, novel technologies being implemented also diagnostics that include isothermal amplification techniques, lateral flow assays, CRISPR‐Cas‐based systems, as well microfluidics, paperfluidics lab‐on‐a‐chip devices, ideal point‐of‐care decentralized settings. In this review, we first evaluate current commercial tests, followed by description advanced technologies, explanation principles, critical evaluation strengths weaknesses, suggestions possible implementation into medical diagnostics.

Language: Английский

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Colorimetric-SERS dual-mode aptasensor for Staphylococcus aureus based on MnO2@AuNPs oxidase-like activity

Food Chemistry, Journal Year: 2024, Volume and Issue: 456, P. 139955 - 139955

Published: June 3, 2024

Language: Английский

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Electrical impedance spectroscopy for skin layer assessment: A scoping review of electrode design, measurement methods, and post-processing techniques

Measurement, Journal Year: 2024, Volume and Issue: 226, P. 114111 - 114111

Published: Jan. 4, 2024

Language: Английский

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Electrochemical Sensors and Biosensors: Effective Tools for Detecting Heavy Metals in Water and Food with Possible Implications for Children's Health

International Journal of Electrochemical Science, Journal Year: 2024, Volume and Issue: 19(8), P. 100643 - 100643

Published: May 21, 2024

Heavy metals are considered to seriously threatens food safety and children's health. Children particularly vulnerable environmental threats because they respond differently stressors than adults, largely due their immature immune systems. Thus, highly sensitive specific technology is urgently required detect toxic heavy in rapidly. This review aims present electrochemical (bio)sensors for detecting metals, especially focusing on nickel, lead, cadmium, mercury, arsenic, aluminum, with the various electrode modification materials provide a broad overview of toxicosis as background sustained investigations toxicology these compounds children health importance.

Language: Английский

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