Sensors and Actuators B Chemical, Год журнала: 2023, Номер 399, С. 134810 - 134810
Опубликована: Окт. 18, 2023
Язык: Английский
Applied Microbiology, Год журнала: 2023, Номер 3(3), С. 629 - 665
Опубликована: Июнь 26, 2023
Biofilm formation can lead to problems in healthcare, water distribution systems, food processing and packaging, industrial manufacturing, marine industries, sanitation. These microbial communities proliferate on biotic or abiotic surfaces, are responsible for human disease decreasing production efficiency service equipment life many fields. The of biofilm starts with the attachment bacteria surface, followed by bacterial proliferation maturation community. After forming a biofilm, not resistant antimicrobial agents their planktonic forms turn resistant. antibiotic resistance association biofilms generating infectious diseases humans, highlight need designing novel successful antibacterial, anti-biofilm, anti-infection materials. This paper aims review mechanism formation, impact different interaction nanoparticles bacteria, strategies design anti-biofilm Examples bio-implants, coatings, medical devices, wound dressings, sutures reviewed.
Язык: Английский
Процитировано
73
Environmental Technology & Innovation, Год журнала: 2024, Номер 34, С. 103625 - 103625
Опубликована: Апрель 4, 2024
Contaminants, such as nucleic acids or toxic small molecules, threaten both human health and ecosystems when they infiltrate the environment. The precise highly sensitive identification of contaminants holds paramount importance across diverse domains, including safeguarding food integrity, facilitating clinical diagnostics, monitoring environmental conditions. Traditional methodologies, encompassing spectroscopy, chromatography, sequencing, metagenomics, have conventionally served pivotal roles in detection processes. Nevertheless, these methods encountered recurring challenges related to sensitivity, specificity, portability. This review focuses on groundbreaking CRISPR/Cas12-based biosensors. These biosensors leverage incredible precision programmability CRISPR/Cas system recognize specific targets. Here, we comprehensively assess fundamental mechanisms that enable detection, ranging from guide RNA design collateral cleavage. versatility CRISPR/Cas12 becomes evident through their applications. applications encompass medical safety, monitoring. transition conventional ultimately represents a significant milestone contaminant detection. By incorporating molecular biology, nanotechnology, bioinformatics, potential reshape landscape water CRIPSR-Cas diagnostics is transformative technology paves way for safer healthier future environment life.
Язык: Английский
Процитировано
16
The Science of The Total Environment, Год журнала: 2021, Номер 803, С. 149834 - 149834
Опубликована: Авг. 21, 2021
Язык: Английский
Процитировано
68
Environmental Nanotechnology Monitoring & Management, Год журнала: 2022, Номер 18, С. 100756 - 100756
Опубликована: Ноя. 12, 2022
Язык: Английский
Процитировано
45
Nature Communications, Год журнала: 2022, Номер 13(1)
Опубликована: Июнь 16, 2022
In this study, we perform a thermal curve analysis with terahertz (THz) metamaterials to develop label-free identification tool for pathogens such as bacteria and yeasts. The resonant frequency of the metasensor coated bacterial layer changes function temperature; provides unique fingerprint specific individual microbial species without use fluorescent dyes antibodies. Differential curves obtained from temperature-dependent resonance exhibit peaks consistent phases, growth, inactivation, DNA denaturation, cell wall destruction. addition, can distinguish gram-negative gram-positive which show strong in temperature range Finally, THz melting on mixture pathogenic are successfully distinguished each other, is essential practical clinical environmental applications blood culture.
Язык: Английский
Процитировано
40
Food Chemistry, Год журнала: 2023, Номер 426, С. 136611 - 136611
Опубликована: Июнь 12, 2023
Язык: Английский
Процитировано
23
ACS Synthetic Biology, Год журнала: 2024, Номер 13(6), С. 1600 - 1620
Опубликована: Июнь 6, 2024
Antimicrobial resistance (AMR) poses a critical global One Health concern, ensuing from unintentional and continuous exposure to antibiotics, as well challenges in accurate contagion diagnostics. Addressing AMR requires strategic approach that emphasizes early stage prevention through screening clinical, environmental, farming, livestock settings identify nonvulnerable antimicrobial agents the associated genes. Conventional diagnostics, like antibiotic susceptibility testing, possess drawbacks, including high costs, time-consuming processes, significant manpower requirements, underscoring need for intelligent, prompt, on-site diagnostic techniques. Nanoenabled artificial intelligence (AI)-supported smart optical biosensors present potential solution by facilitating rapid point-of-care detection with real-time, sensitive, portable capabilities. This Review comprehensively explores various types of nanobiosensors, such surface plasmon resonance sensors, whispering-gallery mode coherence tomography, interference reflection imaging surface-enhanced Raman spectroscopy, fluorescence microring tweezer biosensors, By harnessing unique advantages these nanoenabled revolutionary paradigm shift diagnostics can be achieved, characterized results, sensitivity, portability, integration Internet-of-Things (IoT) technologies. Moreover, enable personalized monitoring detection, significantly reducing turnaround time eliminating human resources needed sample preservation transportation. Their holistic environmental surveillance further enhances capabilities diverse settings, leading improved modern-age healthcare practices more effective management treatments. Embracing advanced tools promises bolster capacity combat safeguard Health.
Язык: Английский
Процитировано
15
Measurement, Год журнала: 2024, Номер 226, С. 114111 - 114111
Опубликована: Янв. 4, 2024
Язык: Английский
Процитировано
12
Journal of Medical Virology, Год журнала: 2024, Номер 96(2)
Опубликована: Янв. 31, 2024
Abstract Persistent infection with high‐risk types of human papillomaviruses (HPV) is a major cause cervical cancer, and an important factor in other malignancies, for example, head neck cancer. Despite recent progress screening vaccination, the incidence mortality are still relatively high, especially low‐income countries. The financial burden associated treatment could be decreased if simple, rapid, inexpensive technology HPV testing becomes available, targeting individuals further monitoring increased risk developing Commercial tests available market often expensive, time‐consuming, require sophisticated instrumentation, which limits their more widespread utilization. To address these challenges, novel technologies being implemented also diagnostics that include isothermal amplification techniques, lateral flow assays, CRISPR‐Cas‐based systems, as well microfluidics, paperfluidics lab‐on‐a‐chip devices, ideal point‐of‐care decentralized settings. In this review, we first evaluate current commercial tests, followed by description advanced technologies, explanation principles, critical evaluation strengths weaknesses, suggestions possible implementation into medical diagnostics.
Язык: Английский
Процитировано
12
International Journal of Electrochemical Science, Год журнала: 2024, Номер 19(8), С. 100643 - 100643
Опубликована: Май 21, 2024
Heavy metals are considered to seriously threatens food safety and children's health. Children particularly vulnerable environmental threats because they respond differently stressors than adults, largely due their immature immune systems. Thus, highly sensitive specific technology is urgently required detect toxic heavy in rapidly. This review aims present electrochemical (bio)sensors for detecting metals, especially focusing on nickel, lead, cadmium, mercury, arsenic, aluminum, with the various electrode modification materials provide a broad overview of toxicosis as background sustained investigations toxicology these compounds children health importance.
Язык: Английский
Процитировано
12