Capacitance Contribution of NIH/3T3 Cells Existing on and between Electrodes of an Impedance Biosensor DOI Creative Commons
Yeeun Kim, Dahyun Kang,

Seokgyu Kim

et al.

Biosensors, Journal Year: 2023, Volume and Issue: 13(11), P. 970 - 970

Published: Nov. 6, 2023

In this study, an impedance biosensor capable of real-time monitoring the growth and drug reactions using NIH/3T3 cells was fabricated through a semiconductor process. With biosensor, cell reaction states are monitored in real-time, showing validness developed biosensor. By we have investigated capacitance contribution existing on electrodes between electrodes. To compare value contributions electrodes, wide- narrow-gap electrode patterns manufactured with 3.7 0.3 mm gap spacings, respectively. From detailed analysis, estimated around less than 20 percent compared to other words, minimized area maximized spacing is promising design guide for accurate measurements.

Language: Английский

Recent advances in point of care testing for COVID-19 detection DOI Open Access
Renata Salgado Fernandes, Juliana de Oliveira Silva, Karina Braga Gomes

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2022, Volume and Issue: 153, P. 113538 - 113538

Published: Aug. 12, 2022

The World Health Organizations declaration of the COVID-19 pandemic was a milestone for scientific community. high transmission rate and huge number deaths, along with lack knowledge about virus evolution disease, stimulated relentless search diagnostic tests, treatments, vaccines. main challenges were differential diagnosis development specific, rapid, sensitive tests that could reach all people. RT-PCR remains gold standard diagnosing COVID-19. However, new methods, such as other molecular techniques immunoassays emerged. Also, need accessible quick results boosted point care (POCT) are fast, automated, precision accuracy. This assay reduces dependence on laboratory conditions mass testing population, dispersing pressure regarding screening detection. review summarizes advances in field since started, emphasizing various detecting We reviewed existing well POCT under development, starting detection, but also exploring nucleic acid techniques, digital PCR, loop-mediated isothermal amplification-based (RT-LAMP), clustered regularly interspaced short palindromic repeats (CRISPR), next-generation sequencing (NGS), immunoassay nanoparticle-based biosensors, developed portable instruments rapid

Language: Английский

Citations

47

Split Ring Resonator-Based Multimode Plasmonic Optical Biosensors for Comprehensive Antigen Detection DOI

Ali Khodaie,

Hamid Heidarzadeh

Sensing and Imaging, Journal Year: 2024, Volume and Issue: 25(1)

Published: Oct. 19, 2024

Language: Английский

Citations

11

Recent advances in the potential applications of luminescence-based, SPR-based, and carbon-based biosensors DOI Open Access

Uttpal Anand,

Arvind K. Singh Chandel, Patrik Olekšák

et al.

Applied Microbiology and Biotechnology, Journal Year: 2022, Volume and Issue: 106(8), P. 2827 - 2853

Published: April 1, 2022

Language: Английский

Citations

36

Biocompatible materials for next-generation biosensors DOI Creative Commons
Gideon Okibe, Humphrey Sam Samuel,

Isah Adeiza Okino

et al.

Discover Chemistry., Journal Year: 2024, Volume and Issue: 1(1)

Published: Oct. 25, 2024

Biosensor is a revolutionary diagnostic tool that harnesses the synergy of biology and technology to detect quantify target analytes, enabling real-time monitoring, early disease diagnosis, innovative applications. Recent advancements in biocompatible materials have brought about significant transformation development biosensors. These tools are essential modern healthcare diagnostics environmental monitoring. This article highlights crucial role enhancing performance safety next-generation Innovative substances such as graphene, hydrogels, nanocomposites been developed, significantly improving sensor functionality compatibility with biological systems. However, challenges associated deploying these include scalability, manufacturing processes, long-term stability. emphasizes transformative potential advancing biosensor technologies expanding their applications across various fields. Detailed analysis illustrates how contribute evolution biosensors, offering more precise, reliable, accessible diagnostics.

Language: Английский

Citations

4

Advances in Biosensing Technologies for Diagnosis of COVID-19 DOI Creative Commons
Sulaiman Alsalameh, Khalid Alnajjar, Tariq Makhzoum

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 898 - 898

Published: Oct. 20, 2022

The COVID-19 pandemic has severely impacted normal human life worldwide. Due to its rapid community spread and high mortality statistics, the development of prompt diagnostic tests for a massive number samples is essential. Currently used traditional methods are often expensive, time-consuming, laboratory-based, unable handle large specimens in resource-limited settings. Because contagiousness, efficient identification SARS-CoV-2 carriers crucial. As advantages adopting biosensors diagnosis increase, this narrative review summarizes recent advances respective reasons consider applying biosensors. Biosensors most sensitive, specific, rapid, user-friendly tools having potential deliver point-of-care diagnostics beyond standards. This provides brief introduction conventional their disadvantages. It also discusses pathogenesis COVID-19, biomarkers, using biosensor technology. current advancements biosensing technologies, from academic research commercial achievements, have been emphasized publications. We covered wide range topics, including biomarker detection, viral genomes, proteins, immune responses infection, other proinflammatory biomolecules. Major challenges prospects future application settings highlighted.

Language: Английский

Citations

19

State-of-the-Art Smart and Intelligent Nanobiosensors for SARS-CoV-2 Diagnosis DOI Creative Commons

Sushma Thapa,

Kshitij RB Singh,

Ranjana Verma

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(8), P. 637 - 637

Published: Aug. 13, 2022

The novel coronavirus appeared to be a milder infection initially, but the unexpected outbreak of severe acute respiratory syndrome 2 (SARS-CoV-2), commonly called COVID-19, was transmitted all over world in late 2019 and caused pandemic. Human health has been disastrously affected by SARS-CoV-2, which is still evolving causing more serious concerns, leading innumerable loss lives. Thus, this review provides an outline traditional tools diagnose role emerging nanomaterials with unique properties for fabricating biosensor devices SARS-CoV-2. Smart intelligent nanomaterial-enabled biosensors (nanobiosensors) have already proven their utility diagnosis several viral infections, as various detection strategies based on nanobiosensor are present, other methods also being investigated researchers determination SARS-CoV-2 disease; however, considerably undetermined yet explored. Hence, highlights determination. Further, it emphasizes future outlook nanobiosensing technologies diagnosis.

Language: Английский

Citations

18

Biosensors and Wearable Technologies for Early Detection and Monitoring of Tropical Diseases DOI
Matthew Chidozie Ogwu, Sylvester Chibueze Izah

Health information science, Journal Year: 2025, Volume and Issue: unknown, P. 57 - 81

Published: Jan. 1, 2025

Language: Английский

Citations

0

Viral Contamination of Food DOI
Long Ma,

Weipan Peng,

Junjie Wang

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 79 - 92

Published: Jan. 1, 2025

Language: Английский

Citations

0

COVID-19 Early Detection in Doctors and Healthcare Workers (CEDiD) study: a cohort study on the feasibility of wearable devices DOI Creative Commons
Alexander Zargaran, Sara Sousi, Gary Colville

et al.

BMJ Open, Journal Year: 2025, Volume and Issue: 15(4), P. e089598 - e089598

Published: April 1, 2025

Background Infectious agents such as SARS-CoV-2 require strategies to contain outbreaks, particularly in hospitals where the spread of infection is most likely. Biometric monitoring heart rate, temperature, oxygen saturations and sleep might provide important early warning signs for SARS-CoV-2. This study aimed determine whether a smart medical device (E4 wristband) pulse oximeter used continuously measure skin temperature saturation would predict onset infection. Methods A single-centre, prospective observational cohort 30 healthcare workers (HCWs) working areas at high risk exposure were enrolled. HCWs tested using RT-qPCR daily self-administered swabs days. Each participant was asked wear an E4 wristband changes their throughout study. Results Nine (30%) (median (range) age 39 (27–57) years) positive COVID-19. No significant differences found pre-infection post-infection variations rate (p=0.31) or (p=0.44). Seven nine subjects reported symptoms some point during period: unusual fatigue (40%), headache (33%) runny nose (22%) frequent. Analysis trends observations demonstrated fluctuations biometric parameters. Conclusion These results suggest that wearable technology be useful documenting exposed HCWs. Trial registration number NCT04363489 .

Language: Английский

Citations

0

Ultra-sensitive heterojunction double gate BioTFET device for SARS-CoV-2 biomolecules detection DOI Creative Commons
P. Vimala,

A. Sharon Geege,

N. Mohankumar

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 30, 2025

Language: Английский

Citations

0