A Pump-Free Optofluidic Biosensing Platform Based on Whispering Gallery Mode Microspheres DOI
Bin Guan, Tuckweng Kok, Nicolas Riesen

et al.

IEEE Sensors, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 4

Published: Oct. 29, 2023

Optofluidic biosensors offer significant advantages for lab-on-a-chip chemical and biological analysis by combining microfluidics small-volume liquid manipulation with the high sensitivity adaptability of optical sensing techniques. In this study, we present an optofluidic biosensing platform utilising a micropillar array coupled active whispering gallery mode (WGM) microsphere resonators rapid detection influenza viruses. The WGM microspheres are coated polyclonal antibodies capable targeting both intact virus fragments viral proteins. facilitates continuous sampling measurement through evaporation-driven fluid transport.

Language: Английский

基于耦合腔类电磁诱导透明的气体传感研究 DOI

谢显龙 Xie Xianlong,

Lei Zhu,

徐文斌 Xu Wenbin

et al.

Chinese Journal of Lasers, Journal Year: 2025, Volume and Issue: 52(1), P. 0113001 - 0113001

Published: Jan. 1, 2025

Citations

0

Microsphere-Enabled Micropillar Array for Whispering Gallery Mode Virus Detection DOI
Bin Guan, Tuckweng Kok, Nicolas Riesen

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(9), P. 12042 - 12051

Published: Feb. 21, 2024

Rapid detection of pathogens and analytes at the point care offers an opportunity for prompt patient management public health control. This paper reports open microfluidic platform coupled with active whispering gallery mode (WGM) microsphere resonators rapid influenza viruses. The WGM resonators, precoated A polyclonal antibodies, are mechanically trapped in micropillar array, where evaporation-driven flow continuously transports a small volume (∼μL) sample to without auxiliaries. Selective chemical modification pillar array changes surface wettability pattern, which enhances sensitivity resonator-based virus sensor. optofluidic sensing is able specifically detect viruses within 15 min using few microliters displays linear response different concentrations.

Language: Английский

Citations

3

Microfluidics and Nanofluidics in Strong Light–Matter Coupling Systems DOI Creative Commons
Evelyn Granizo, Irina Kriukova, Pedro Escudero‐Villa

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(18), P. 1520 - 1520

Published: Sept. 19, 2024

The combination of micro- or nanofluidics and strong light-matter coupling has gained much interest in the past decade, which led to development advanced systems devices with numerous potential applications different fields, such as chemistry, biosensing, material science. Strong is achieved by placing a dipole (e.g., an atom molecule) into confined electromagnetic field, molecular transitions being resonance field strength exceeding average dissipation rate. Despite intense research encouraging results this some challenges still need be overcome, related fabrication nano- microscale optical cavities, stability, scaling up production, sensitivity, signal-to-noise ratio, real-time control monitoring. goal paper summarize recent developments nanofluidic employing coupling. An overview various methods techniques used achieve presented, preceded brief outline fundamentals optofluidics operating regime. these integrated sensing, optofluidics, quantum technologies are explored. prospects rapidly developing discussed.

Language: Английский

Citations

3

Feature Papers in Optical Sensors 2022 DOI Creative Commons
Vittorio M. N. Passaro, Yuliya Semenova, Benjamin L. Miller

et al.

Sensors, Journal Year: 2023, Volume and Issue: 23(7), P. 3696 - 3696

Published: April 3, 2023

Today, optical sensors are the subject of a very significant number studies and applications [...].

Language: Английский

Citations

1

A Pump-Free Optofluidic Biosensing Platform Based on Whispering Gallery Mode Microspheres DOI
Bin Guan, Tuckweng Kok, Nicolas Riesen

et al.

IEEE Sensors, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 4

Published: Oct. 29, 2023

Optofluidic biosensors offer significant advantages for lab-on-a-chip chemical and biological analysis by combining microfluidics small-volume liquid manipulation with the high sensitivity adaptability of optical sensing techniques. In this study, we present an optofluidic biosensing platform utilising a micropillar array coupled active whispering gallery mode (WGM) microsphere resonators rapid detection influenza viruses. The WGM microspheres are coated polyclonal antibodies capable targeting both intact virus fragments viral proteins. facilitates continuous sampling measurement through evaporation-driven fluid transport.

Language: Английский

Citations

0