Natural Product Research,
Journal Year:
2022,
Volume and Issue:
37(11), P. 1917 - 1934
Published: Sept. 12, 2022
Chronic
urticaria
(CU)
is
a
pathologic
condition
marked
by
the
emergence
of
wheals,
angioedema,
or
both
for
more
than
six
weeks.
The
improper
activation
and
degranulation
mast
cells
triggering
event,
which
results
in
production
various
mediators
such
as
histamine,
leukotrienes,
PAF,
chemokines,
cytokines.
Antihistamines
are
currently
most
common
pharmacological
treatment
urticaria,
but
corticosteroids
monoclonal
antibodies
can
also
be
employed.
Patients
who
have
been
taking
antihistamines
long
time
often
looking
alternatives.
Whole
plants,
portions
single
extracted
active
compounds
all
used
phytomedicine.
Plant
elements
frequently
combined
to
create
formulations
that
utilized
treat
variety
pathological
disorders.
Anti-inflammatory
and/or
anti-allergic
properties
found
several
herbs
regularly
herbal
formulations.
Antioxidant
present
some
constituents.
Exogenous
antioxidants
shown
improve
progression
autoimmune
disorders
numerous
studies.
aim
this
review
identify
chronic
characterize
their
efficacy,
mechanisms
action,
risk/benefit
ratio
comparison
western
treatment,
find
less
assess
therapeutic
safety
profile,
potential
wider
use.
Natural Product Research,
Journal Year:
2022,
Volume and Issue:
37(5), P. 798 - 802
Published: June 16, 2022
This
study
aimed
to
investigate
the
protective
effects
and
mechanisms
of
myricetin
on
acute
liver
failure
in
mice
induced
by
lipopolysaccharide
(LPS)/D-galactosamine
(D-Gal).
Our
results
showed
(25,
50
100
mg/kg)
pretreatment
significantly
improved
pathological
changes
tissues,
decreased
serum
ALT
AST
(p
<
0.001)
LPS/D-GalN.
Moreover,
MDA
MPO
levels
were
reduced
0.001),
CAT
SOD
activities
increased
with
(50
pretreatment.
Likewise,
inflammatory
cytokines
TNF-α
IL-6
mRNA
tissues
markedly
myricetin.
Besides,
Nrf2
protein
expression
was
drastically
elevated
mg/kg).
All
these
findings
imply
that
may
protect
against
suppressing
inflammation
regulating
oxidative
stress
via
signaling,
it
be
a
possible
strategy
avoid
damage.
Acta Histochemica,
Journal Year:
2023,
Volume and Issue:
125(3), P. 152031 - 152031
Published: April 1, 2023
The
integument
acts
as
a
barrier
to
protect
the
body
from
harmful
pathogenic
infectious
agents,
parasites,
UV
rays,
trauma,
and
germs.
of
invertebrates
vertebrates
are
structurally
different:
while
usually
have
simple
monolayer
epidermis
frequently
covered
by
mucus,
cuticles,
or
mineralized
structures,
possess
multilayered
with
several
specialized
cells.
This
study
aims
describe
morphological,
histological,
immunohistochemical
analyses,
morpho-structural
adaptations
throughout
evolution
gastropod
Aplysia
depilans
(Gmelin,
1791),
ascidian
Styela
plicata
(Lesuer,
1823),
myxine
hagfish
Eptatretus
cirrhatus
(Forster,
1801)
teleost
Heteropneustes
fossilis
(Bloch,
1794)
for
first
time,
special
reference
sensory
epidermal
Different
types
cells
could
be
identified
that
varied
according
species;
including
mucous
cells,
serous
glandular
clavate
club
thread
support
In
all
integuments
specimens
analyzed,
solitary
were
in
epidermis,
immunoreactive
serotonin
calbindin.
Our
provided
an
essential
comparison
integuments,
adding
new
information
about
phylogenetic
conservation
on
structural
changes
undergone
during
evolution.
Toxics,
Journal Year:
2023,
Volume and Issue:
11(9), P. 731 - 731
Published: Aug. 25, 2023
The
introduction
of
pollutants,
such
as
thiacloprid
and
benzo[a]pyrene
(B[a]P),
into
the
waters
urbanized
coastal
estuarine
areas
through
fossil
fuel
spills,
domestic
industrial
waste
discharges,
atmospheric
inputs,
continental
runoff
poses
a
major
threat
to
fauna
flora
aquatic
environment
can
have
significant
impact
on
internal
defense
system
invertebrates
mussels.
Using
monoclonal
polyclonal
anti-Toll-like
receptor
2
(TLR2)
anti-inducible
nitric
oxide
synthetase
(iNOS)
antibodies
for
first
time,
this
work
aims
examine
hemocytes
in
mantle
gills
M.
galloprovincialis
biomarkers
B[a]P
pollution
analyze
their
potential
synergistic
effect.
To
pursue
objective,
samples
were
exposed
both
individually
simultaneously.
Subsequently,
oxidative
stress
evaluated
by
enzymatic
analysis,
while
tissue
changes
number
different
contaminated
groups
assessed
via
histomorphological
immunohistochemical
analyses.
Our
findings
revealed
that
comparison
single
exposure,
two
pollutants
together
significantly
elevated
stress.
Moreover,
our
data
may
potentially
enhance
knowledge
how
TLR2
iNOS
part
bivalves.
This
would
help
creating
new
technologies
strategies,
biosensors,
are
more
suitable
managing
water
pollution,
garnering
details
condition
marine
ecosystem.
Natural Product Research,
Journal Year:
2022,
Volume and Issue:
37(11), P. 1917 - 1934
Published: Sept. 12, 2022
Chronic
urticaria
(CU)
is
a
pathologic
condition
marked
by
the
emergence
of
wheals,
angioedema,
or
both
for
more
than
six
weeks.
The
improper
activation
and
degranulation
mast
cells
triggering
event,
which
results
in
production
various
mediators
such
as
histamine,
leukotrienes,
PAF,
chemokines,
cytokines.
Antihistamines
are
currently
most
common
pharmacological
treatment
urticaria,
but
corticosteroids
monoclonal
antibodies
can
also
be
employed.
Patients
who
have
been
taking
antihistamines
long
time
often
looking
alternatives.
Whole
plants,
portions
single
extracted
active
compounds
all
used
phytomedicine.
Plant
elements
frequently
combined
to
create
formulations
that
utilized
treat
variety
pathological
disorders.
Anti-inflammatory
and/or
anti-allergic
properties
found
several
herbs
regularly
herbal
formulations.
Antioxidant
present
some
constituents.
Exogenous
antioxidants
shown
improve
progression
autoimmune
disorders
numerous
studies.
aim
this
review
identify
chronic
characterize
their
efficacy,
mechanisms
action,
risk/benefit
ratio
comparison
western
treatment,
find
less
assess
therapeutic
safety
profile,
potential
wider
use.
