ChemBioChem,
Journal Year:
2024,
Volume and Issue:
25(9)
Published: March 15, 2024
This
review
focuses
on
discussing
natural
products
(NPs)
that
contain
higher
homologated
amino
acids
(homoAAs)
in
the
structure
as
well
proposed
and
characterized
biosynthesis
of
these
non-proteinogenic
acids.
Homologation
includes
insertion
a
methylene
group
into
its
side
chain.
It
is
not
very
common
modification
found
NP
approximately
450
homoAA-containing
NPs
have
been
isolated
from
four
bacterial
phyla
(Cyanobacteria,
Actinomycetota,
Myxococcota,
Pseudomonadota),
two
fungal
(Ascomycota
Basidiomycota),
one
animal
phylum
(Porifera),
except
for
few
examples.
Amino
are
to
be
incorporated
structures
include
following
ten
acids:
alanine,
arginine,
cysteine,
isoleucine,
glutamic
acid,
leucine,
phenylalanine,
proline,
serine,
tyrosine,
where
tyrosine
share
comparable
enzymatic
pathway.
Other
their
individual
homologation
pathway
(arginine,
acid
bacteria),
likely
utilize
primary
metabolic
(alanine
fungi),
or
reported
(cysteine
serine).
Despite
possible
high
potential
drug
discovery
field,
has
large
room
explore
future
combinatorial
engineering
purpose.
Water Research,
Journal Year:
2024,
Volume and Issue:
255, P. 121497 - 121497
Published: March 19, 2024
Microcystins
(MCs)
constitute
a
significant
threat
to
human
and
environmental
health,
urging
the
development
of
effective
removal
methods
for
these
toxins.
In
this
review,
we
explore
potential
MC-degrading
bacteria
as
solution
MCs
from
water.
The
review
insights
into
mechanisms
action
employed
by
bacteria,
elucidating
their
ability
degrade
thus
remove
MCs.
After,
points
out
influence
structural
conformation
on
removal,
particularly
stability
at
different
water
depths
within
bodies.
Then,
crucial
role
played
production
in
ensuring
survival
safeguarding
enzymatic
activities
Microcystis
cells.
This
justifies
need
developing
sustainable
removing
aquatic
ecosystems,
given
critical
ecological
function
toxicity
humans
animals.
Thereafter,
challenges
limitations
associated
with
using
treatment
are
discussed,
emphasizing
further
research
optimize
selection
bacterial
strains
used
biodegradation.
interaction
MCs-degrading
sediment
particles
is
also
toxin
its
efficiency.
By
presenting
information,
valuable
resource
researchers,
policymakers,
stakeholders
involved
practical
approaches
Our
highlights
various
applications
including
multi-soil-layering
(MSL)
technologies.
It
emphasizes
ongoing
utilization
treatment,
ultimately
safety
quality
sources.
Moreover,
value
bibliometric
analyses
revealing
gaps
trends,
providing
detailed
investigations.
Specifically,
discuss
importance
employing
advanced
genomics,
especially
combining
OMICS
identify
bacteria.
Harmful Algae,
Journal Year:
2024,
Volume and Issue:
134, P. 102627 - 102627
Published: April 1, 2024
Due
to
climate
changes
and
eutrophication,
blooms
of
predominantly
toxic
freshwater
cyanobacteria
are
intensifying
likely
colonize
estuaries,
thus
impacting
benthic
organisms
shellfish
farming
representing
a
major
ecological,
health
economic
risk.
In
the
natural
environment,
Microcystis
form
large
mucilaginous
colonies
that
influence
development
both
cyanobacterial
embedded
bacterial
communities.
However,
little
is
known
about
fate
by
salinity
increase.
this
study,
we
monitored
dominated
bloom
its
microbiome
along
French
freshwater-marine
gradient
at
different
phases
bloom.
We
demonstrated
in
genotypic
composition,
production
specific
metabolites
(toxins
compatible
solutes)
heterotrophic
bacteria
structure
response
particular
M.
aeruginosa
wesenbergii
survived
salinities
up
20.
Based
on
microcystin
gene
abundance,
became
more
during
their
estuarine
transfer
but
with
no
selection
variants.
An
increase
solutes
occurred
continuum
extensive
trehalose
betaine
accumulations.
Salinity
structured
most
community,
an
increased
richness
diversity
continuum.
A
core
mucilage-associated
attached
fraction
was
highly
abundant
suggesting
strong
interaction
between
protecting
role
mucilage
against
osmotic
shock.
These
results
underline
need
better
determine
interactions
as
key
widespread
success
adaptation
various
environmental
conditions.
Fuels,
Journal Year:
2024,
Volume and Issue:
5(3), P. 394 - 438
Published: Aug. 27, 2024
This
comprehensive
review
investigates
the
potential
of
cyanobacteria,
particularly
nitrogen-fixing
strains,
in
addressing
global
challenges
pertaining
to
plastic
pollution
and
carbon
emissions.
By
analyzing
distinctive
characteristics
including
their
minimal
growth
requirements,
high
photosynthetic
efficiency,
rapid
rates,
this
study
elucidates
crucial
role
transforming
sequestration,
biofuel
generation,
biodegradable
production.
The
investigation
emphasizes
cyanobacteria’s
efficiency
photosynthesis,
positioning
them
as
optimal
candidates
for
cost-effective
bioplastic
production
with
minimized
land
usage.
Furthermore,
explores
unconventional
yet
promising
utilization
biodiesel
production,
mitigating
environmental
concerns
such
sulfur
emissions
presence
aromatic
hydrocarbons.
resulting
exhibits
significant
combustion
potential,
establishing
cyanobacteria
a
viable
option
sustainable
Through
assessment
both
achievements
encountered
during
commercialization
process,
offers
valuable
insights
into
diverse
contributions
cyanobacteria.
Its
objective
is
provide
guidance
researchers,
policymakers,
industries
interested
harnessing
bio-inspired
approaches
structural
applications,
thereby
advancing
efforts
towards
environmentally
conscious
ChemBioChem,
Journal Year:
2024,
Volume and Issue:
25(9)
Published: March 15, 2024
This
review
focuses
on
discussing
natural
products
(NPs)
that
contain
higher
homologated
amino
acids
(homoAAs)
in
the
structure
as
well
proposed
and
characterized
biosynthesis
of
these
non-proteinogenic
acids.
Homologation
includes
insertion
a
methylene
group
into
its
side
chain.
It
is
not
very
common
modification
found
NP
approximately
450
homoAA-containing
NPs
have
been
isolated
from
four
bacterial
phyla
(Cyanobacteria,
Actinomycetota,
Myxococcota,
Pseudomonadota),
two
fungal
(Ascomycota
Basidiomycota),
one
animal
phylum
(Porifera),
except
for
few
examples.
Amino
are
to
be
incorporated
structures
include
following
ten
acids:
alanine,
arginine,
cysteine,
isoleucine,
glutamic
acid,
leucine,
phenylalanine,
proline,
serine,
tyrosine,
where
tyrosine
share
comparable
enzymatic
pathway.
Other
their
individual
homologation
pathway
(arginine,
acid
bacteria),
likely
utilize
primary
metabolic
(alanine
fungi),
or
reported
(cysteine
serine).
Despite
possible
high
potential
drug
discovery
field,
has
large
room
explore
future
combinatorial
engineering
purpose.
