Élelmiszervizsgálati Közlemények,
Journal Year:
2023,
Volume and Issue:
69(1), P. 4317 - 4336
Published: March 31, 2023
Tropane
alkaloids
occur
in
many
plant
families
and
their
toxic
effects
can
cause
mild
symptoms
or
even
death,
depending
on
the
dose.
They
are
most
commonly
introduced
into
human
body
through
contamination,
misuse
deliberate
abuse
due
to
intoxicating
effects.
present
food
for
general
consumption,
sometimes
causing
documented
poisoning,
inadequate
cleaning
of
cereals,
pulses
other
grain
crops,
but
especially
organic
products
produced
without
chemicals.
The
EU
legislation
published
2021
set
tolerances
tropane
a
relatively
wide
range
materials,
therefore
consistent
compliance
with
regulation
will
reduce
safety
risk
from
alkaloid
although
poisoning
incidents
recent
years
have
highlighted
need
broaden
substances
covered.
Advances in Sample Preparation,
Journal Year:
2023,
Volume and Issue:
6, P. 100056 - 100056
Published: Feb. 24, 2023
Sample
preparation
methods
tend
to
be
fast,
simple,
with
the
use
of
new
adsorbents
and
lower
amounts
organic
solvents
make
them
more
environmentally
friendly.
In
this
work,
a
magnetic
solid-phase
extraction
(MSPE)
protocol
for
quantification
six
opium
alkaloids
(OAs)
in
poppy
seeds
infusions
has
been
optimised
followed
by
analysis
liquid
chromatography
coupled
tandem
mass
spectrometry
(HPLC-MS/MS).
For
purpose,
mesostructured
silica
composite
β-CD
(Fe3O4@SiO2@mSiO2@β-CD)
was
synthesised
characterized.
To
obtain
highest
level
functionalisation,
three
proportions
monomer/material
(12.5,
25
100%)
were
determined,
demonstrating
that
25%
showed
level.
Adsorption
studies
carried
out
water
at
different
pH
(1,
2,
7,
9
11)
times
5,
10
20
min),
confirming
high
adsorption
capacity
1
min.
Then,
elution
conditions
MSPE
procedure
(50
mg
material,
2
mL
water/EtOH
50%
1%
formic
acid
min).
The
methodology
successful
validated
low
detection
limits,
negligible
matrix
effect
good
recovery
values
(89–94%).
applied
home-made
four
seeds,
observing
one
worrying
amount
OAs
which
imply
content
least
legislation.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(11), P. 3520 - 3520
Published: May 30, 2022
A
novel
dual-template
magnetic
molecularly
imprinted
polymer
(MMIP)
was
synthesized
to
extract
normetanephrine
(NMN),
metanephrine
(MN)
and
3-methoxytyramine
(3-MT)
from
spot
urine
samples.
As
the
adsorbent
of
dispersive
solid-phase
extraction
(d-SPE),
MMIP
prepared
using
dopamine
MN
as
dual
templates,
methacrylic
acid
functional
monomer,
ethylene
glycol
dimethacrylate
crosslinking
reagent
nanoparticles
core.
NMN,
MN,
3-MT
creatinine
(Cr)
in
samples
were
selectively
enriched
by
d-SPE
detected
HPLC-fluorescence
detection/ultraviolet
detection.
The
peak
area
(A)
ratios
Cr
used
for
diagnosis
pheochromocytomas
paragangliomas
(PPGLs).
results
showed
that
adsorption
efficiencies
target
analytes
all
higher
than
89.0%,
coefficient
variation
precisions
intra-assay
inter-assay
within
4.9%
6.3%,
respectively.
recoveries
93.2%
112.8%.
still
14
days
could
be
reused
at
least
seven
times.
recommended
(SPE)
both
pretreat
18
PPGLs
patients
22
healthy
controls.
correlation
coefficients
ANMN/ACr
AMN/ACr
between
SPE
0.95.
In
addition,
areas
under
receiver
operator
curves
ANMN/ACr,
plasma
free
NMN
0.975,
0.773
0.990,
0.821,
respectively,
indicating
two
methods
had
similar
performances.
method
took
only
20
min,
which
effective
clinical
application.
ChemistrySelect,
Journal Year:
2023,
Volume and Issue:
8(12)
Published: March 22, 2023
Abstract
This
work
examines
the
physical
and
chemical
interactions
between
polar
nonpolar
solvents
surface
of
MCM‐41
material,
which
serves
as
isolating
layer,
employing
sensing
capacitance‐voltage
measurements
with
a
Metal‐Insulator‐Semiconductor
(MIS)
capacitor.
It
was
observed
that
is
more
sensitive
to
methanol,
protic
solvent,
than
other
like
chloroform,
according
data.
Furthermore,
by
analyzing
interaction
methanol
function
applied
field,
electron
transfer,
orientation
solvent
molecule,
DFT
Calculations
using
Siesta
simulation
software
enable
us
assess
this
sensitivity.
Based
on
performance
insulator
in
MIS
capacitor,
has
strong
potential
for
creation
high‐sensitivity
sensors
detection
avoiding
functionalization
process.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(6)
Published: Nov. 1, 2024
Food
safety
is
crucial
to
attaining
food
security
and
sustainability.
Unsafe
foods
for
human
animal
consumption
lead
product
recalls
rejection,
negatively
impacting
the
global
economy
trade.
Similarly,
climate
change
can
adversely
affect
availability
of
safe
nutritious
at
table.
The
changing
climatic
conditions
trade
transport
make
movement
toxic
plants
possible,
resulting
in
crops
being
increasingly
invaded
by
some
species
that
produce
secondary
metabolites,
such
as
tropane
alkaloids
(TAs).
Datura
stramonium
from
Solanaceae
plant
family
an
invasive
virulent
produces
high
amounts
two
TAs,
atropine
scopolamine.
Various
poisoning
events
following
accidental
or
deliberate
ingestion
contaminated
scopolamine
seeds
D.
have
been
recorded
different
locations
globally.
Due
these
incidents,
regulatory
agencies
require
development
toxin
detection
methods
be
used
chain
early
possible.
This
systematic
review
thus
focuses
on
TA
determination
techniques
feeds
published
between
2013
2023.
A
particular
focus
was
given
sample
preparation
methods,
improvements
each
technique
claimed,
data
support
performance
method,
especially
ability
measure
below
maximum
level.
concludes
with
other
technological
advancements,
including
rapid
spectroscopy,
electrophoresis,
colorimetric
well
possibility
coupling
smartphones
use
on-farm
challenges
applying
them.
Élelmiszervizsgálati Közlemények,
Journal Year:
2023,
Volume and Issue:
69(1), P. 4295 - 4316
Published: March 31, 2023
A
tropán
alkaloidok
számos
növénycsaládban
előfordulnak,
toxikus
hatásuk
következtében
dózistól
függően
enyhe
tüneteket,
de
akár
halált
is
okozhatnak.
Az
emberi
szervezetbe
leggyakrabban
szennyeződés,
tévesztés
vagy
bódító
miatti
szándékos
visszaélés
kerülnek.
Gabonafélék,
hüvelyesek,
egyéb
szemes
termények,
különösen
a
vegyszermentes
termelésű
biotermékek
nem
megfelelő
tisztítása
általános
közfogyasztásra
szánt
élelmiszerekben
esetenként
dokumentált
mérgezést
okoznak.
2021-ben
megjelent
európai
uniós
szabályozás
növényi
alapanyagok
viszonylag
széles
körére
határozza
meg
megengedhető
mértékét,
így
rendelet
következetes
betartásával
elérhető
lesz
alkaloid
szennyeződésből
eredő
élelmiszerbiztonsági
kockázat
csökkenése,
mindamellett,
hogy
az
utóbbi
évek
élelmiszer-eredetű
mérgezéses
esetei
felhívják
figyelmet
alá
eső
élelmi
anyagok
köre
bővítésének
szükségességére.
Élelmiszervizsgálati Közlemények,
Journal Year:
2023,
Volume and Issue:
69(1), P. 4317 - 4336
Published: March 31, 2023
Tropane
alkaloids
occur
in
many
plant
families
and
their
toxic
effects
can
cause
mild
symptoms
or
even
death,
depending
on
the
dose.
They
are
most
commonly
introduced
into
human
body
through
contamination,
misuse
deliberate
abuse
due
to
intoxicating
effects.
present
food
for
general
consumption,
sometimes
causing
documented
poisoning,
inadequate
cleaning
of
cereals,
pulses
other
grain
crops,
but
especially
organic
products
produced
without
chemicals.
The
EU
legislation
published
2021
set
tolerances
tropane
a
relatively
wide
range
materials,
therefore
consistent
compliance
with
regulation
will
reduce
safety
risk
from
alkaloid
although
poisoning
incidents
recent
years
have
highlighted
need
broaden
substances
covered.
