Right Ventricle Thrombus and COVID-19 Infection: An Uncommon Report of Three Cases DOI Open Access

Manish Mittal,

Bhavin Patel, Dharmesh Patel

et al.

Indian Journal of Critical Care Case Report, Journal Year: 2023, Volume and Issue: 2(6), P. 158 - 160

Published: Dec. 1, 2023

Case seriesthrombolyzed with 100 mg injection actilyse [recombinant tissue plasminogen activator (rt-PA)] over 2 hours.2D-echo was repeated again (Video 2) and showed reduction in the size of thrombus.After 10 days, oxygen requirement reduced to 5-6 L/minute, another 10-11 patient shifted out ICU finally discharged after 24 days admission.Following discharge, advised take dabigatran 150 12 hourly. 2A 29-year-old obese female presented severe COVID-19 pneumonia, SpO at 67% on room air 95% 6 L/minute O mask intensive care unit.Her increased within 36-48 hours admission.

Language: Английский

Immune response variation in mild and severe COVID-19 patients DOI Creative Commons
Samuel Stróż, Piotr Kosiorek, Edyta Zbroch

et al.

Qatar medical journal, Journal Year: 2024, Volume and Issue: 2024(1)

Published: March 6, 2024

Sixty patients with COVID-19 infection were categorized into mild and severe groups, their immune response was analyzed using flow cytometry complete blood count. An observed increase in activation parameters, notably a higher percentage of CD4 lymphocytes co-expressing CD69 CD25 molecules, enhanced activity the macrophage-monocyte cell line noted group. Although Group 2 (severe COVID) had fewer cells, significant migration proliferation evident, increased CD4CD69, CD8 HLA-DR+, CD8CD69 lymphocytes. The to ratio 1 suggested potential autoimmune reactions, while indicated immunosuppression from employing immunosuppressive drugs. Additionally, exhibited an neutrophil count, hinting at possible bacterial co-infection. showed differences CD4RO CD8RA lymphocyte populations, implying that cellular immunity plays role developing efficient postinfectious immunity. This intimation suggests vaccination might mitigate severity coronavirus prevent complications, including long-term COVID-19.

Language: Английский

Citations

1
Post-COVID syndrome and type 2 diabetes mellitus in Kazakhstan: clinical manifestations and vaccine efficacy DOI Creative Commons
Saule Altynbekova,

Zhangentkhan Abylaiuly,

Svetlana Bolshakova

et al.

Annals of Pediatric Endocrinology & Metabolism, Journal Year: 2024, Volume and Issue: 29(5), P. 325 - 336

Published: Oct. 30, 2024

Purpose: In this article, we report the results of a survey investigating post–coronavirus disease 2019 (COVID-19) syndrome in patients with type 2 diabetes mellitus and impacts vaccination on long-term manifestations. From February 2022 to April 2023, people without who were treated for coronavirus infection was conducted Kazakhstan.Methods: Participants invited via social media voluntarily participate study. A total 417 surveys included study, comprising 212 205 diabetes. We compared persistent complaints after recovery (DM), as well status.Results: The study self-reported symptoms prolonged COVID show that more than half those infected severe acute respiratory (SARS-CoV-2) Kazakhstan have at least one symptom recovery. Based list COVID-19 reported by DM (T2DM), exertional dyspnoea, fatigue, discomfort, headaches, sleep disturbances are among most common ongoing conditions, many cases last 3 months COVID-19.Conclusion: Patients T2DM experience Additionally, lowers hospitalization risk decreases need adjusting hypoglycemic therapy, such insulin treatment, recovering from SARS-CoV-2 infection.

Language: Английский

Citations

1
Evaluation of morphological parameters, PLR and NLR inflammation indicators in patients with long-term COVID-19 of mild and severe complexity DOI Open Access
Samuel Stróż, Piotr Kosiorek, Edyta Zbroch

et al.

Polish Annals of Medicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 8

Published: April 24, 2024

Introduction COVID-19 can have long-lasting effects, but the effects on blood parameters and inflammation are poorly understood. The aim of this study was to evaluate morphological inflammatory markers in long-term patients. Aim To complete count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) morphology mild versus severe long COVID-19. Material methods In total, 39 patients were stratified into (<i>n</i> = 25) 14) groups. Blood counts, NLR, PLR measured. Cell analysed. ROC curves used determine biomarker thresholds. Survival assessed using Kaplan–Meier curves. Results discussion Severe had lower leukocytes higher neutrophils, indicating greater inflammation. NLR significantly increased compared (NLR 12 vs 8; 140 100). than controls, confirming their utility as markers. effectively discriminated between disease. High predicted poorer prognosis. Altered leukocyte such cytoplasmic vacuolization correlated with severity. Conclusions promising biomarkers for assessing severity COVID-19, while changes cells provide additional evidence Further studies larger populations warranted.

Language: Английский

Citations

0
Impact of the COVID-19 pandemic on the clinical features of patients with chronic obstructive pulmonary disease: an observational cross-sectional study DOI Creative Commons
Gaukhar Kurmanova,

Almas Zhanaev,

Akzharkyn Kaldybek

et al.

Monaldi Archives for Chest Disease, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

The presence of chronic obstructive pulmonary disease (COPD) and COVID-19 infection is a detrimental combination for patients can cause negative clinical consequences. investigation aimed to compare sociodemographic parameters COPD individuals hospitalized exacerbations before at the end pandemic. An observational cross-sectional study including 222 with was conducted in two stages: survey assessment laboratory data from September 2022 March 2023 (n=98) processing medical histories who received hospital treatment 2017 2018 (n=124). A comparative analysis inpatient showed that frequency Global Initiative Chronic Obstructive Lung Disease (GOLD) I half as high after pandemic, whereas GOLD IV were more frequent during same period (p<0.05). Multiple regression proved effects smoking status previous on health according Assessment Test There an increase comorbid pathologies post-COVID period: hypertension, coronary heart disease, gastrointestinal diseases, anemia (p<0.05), other diseases. This highlights significant influence people COPD, which manifested impaired lung function increased incidence comorbidities.

Language: Английский

Citations

0
Relation of anemia with renal function on prognosis and disease severity in patients with acute pulmonary embolism DOI Open Access
Ömer Furkan Demir

Medical Science and Discovery, Journal Year: 2023, Volume and Issue: 10(8), P. 575 - 580

Published: Aug. 20, 2023

Background: In-hospital mortality for patients presenting with acute pulmonary embolism (PE) has been reported to be up 7 times higher decreased estimated glomerular filtration rate (eGFR). Cardiopulmonary diseases and anemia are other comorbid conditions that suggested prognostic parameters in PE. The severity of PE was associated worsening survival. We aimed investigate the effect on association renal function prognosis disease Patients/Methods: retrospective study enrolled 112 consecutive objectively confirmed Demographic, clinical data, comorbidities laboratory values were recorded. GFR using chronic kidney (CKD)-EPI equations. Simplified index (sPESI) calculated all severe form defined as sPESI ≥1. In hospital primer outcome. Results: univariate analyses, age, eGFR, lung found significantly in-hospital severity. Only age eGFR significant factors early [1.13(1.03-1.24); p=0.007 0.95(0.91 0.98); respectively]. Conclusion: Estimated is independently a more increased risk rates within 30 days independent presence.

Language: Английский

Citations

0
Right Ventricle Thrombus and COVID-19 Infection: An Uncommon Report of Three Cases DOI Open Access

Manish Mittal,

Bhavin Patel, Dharmesh Patel

et al.

Indian Journal of Critical Care Case Report, Journal Year: 2023, Volume and Issue: 2(6), P. 158 - 160

Published: Dec. 1, 2023

Case seriesthrombolyzed with 100 mg injection actilyse [recombinant tissue plasminogen activator (rt-PA)] over 2 hours.2D-echo was repeated again (Video 2) and showed reduction in the size of thrombus.After 10 days, oxygen requirement reduced to 5-6 L/minute, another 10-11 patient shifted out ICU finally discharged after 24 days admission.Following discharge, advised take dabigatran 150 12 hourly. 2A 29-year-old obese female presented severe COVID-19 pneumonia, SpO at 67% on room air 95% 6 L/minute O mask intensive care unit.Her increased within 36-48 hours admission.

Language: Английский

Citations

0