Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: Nov. 9, 2023
Introduction
Coronavirus
Disease
2019
(COVID-19)
presents
a
massive
challenge
in
Africa
due
to
overwhelmed
and
underresourced
health
systems,
as
well
the
existing
burden
of
communicable
non-
diseases.
Self-inoculation
may
occur
when
an
individual
touches
their
mucous
membrane
following
direct
contact
between
hands
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2)-contaminated
surfaces.
Therefore,
handwashing
can
be
used
along
with
COVID-19
vaccines
reduce
spread
SARS-CoV-2
COVID-19.
We
were
interested
investigating
levels
vaccine
uptake
control
prevent
Kenya,
Uganda
Tanzania
using
systematic
review
meta-analysis.
Methods
searched
PubMed,
African
Index
Medicus
Journals
Online
for
studies
published
since
inception
31
st
January
2023.
included
all
that
assessed:
acceptance
hesitance
indicators
uptake;
on
Tanzania.
Study
findings
synthesized
by
meta-analysis
get
pooled
effect
measure.
Three
qualitatively
high
level
heterogeneity
measure
precluding
quantitative
Results
Our
search
identified
128
articles
which
17
18,305
participants
622
vaccination
sites
reviewed
14
them
being
meta-analyzed.
This
reports
at
67%
(95%
CI:
55,
78)
88%
73,
97),
respectively.
Vaccine
among
was
low
31%
15,
49).
Discussion
Despite
importance
prevention
COVID-19,
some
countries
do
not
implement
effectively.
There
is
need
public
strategies
raise
awareness
about
vaccine.
Systematic
Review
Registration
https://www.crd.york.ac.uk/PROSPERO/
,
PROSPERO
ID
CRD42023394698.
Vaccines,
Journal Year:
2022,
Volume and Issue:
10(9), P. 1553 - 1553
Published: Sept. 17, 2022
The
introduction
of
effective
vaccines
in
December
2020
marked
a
significant
step
forward
the
global
response
to
COVID-19.
Given
concerns
with
access,
acceptability,
and
hesitancy
across
Africa,
there
is
need
describe
current
status
vaccine
uptake
continent.
An
exploratory
study
was
undertaken
investigate
these
aspects,
challenges,
lessons
learnt
Africa
provide
future
direction.
Senior
personnel
14
African
countries
completed
self-administered
questionnaire,
descriptive
analysis
data.
Vaccine
roll-out
commenced
March
2021
most
countries.
COVID-19
vaccination
coverage
varied
from
low
Cameroon
Tanzania
up
39.85%
full
Botswana
at
end
2021;
that
is,
all
doses
advocated
by
initial
protocols
versus
total
population,
rates
increasing
58.4%
June
2022.
greatest
increase
people
being
fully
vaccinated
observed
Uganda
(20.4%
increase),
(18.5%
Zambia
(17.9%
increase).
Most
were
obtained
through
WHO-COVAX
agreements.
Initially,
prioritised
for
healthcare
workers
(HCWs),
elderly,
adults
co-morbidities,
other
at-risk
groups,
now
commencing
among
children
administering
booster
doses.
Challenges
included
irregular
supply
considerable
arising
misinformation
fuelled
social
media
activities.
Overall,
fair
reasonable
access
countries,
enhanced
government
initiatives.
must
be
addressed
context-specific
interventions,
including
proactive
programmes
HCWs,
medical
journalists,
public.
Vaccines,
Journal Year:
2023,
Volume and Issue:
11(4), P. 873 - 873
Published: April 20, 2023
The
COVID-19
pandemic
is
a
severe
concern
worldwide,
particularly
in
Africa.
Vaccines
are
crucial
the
fight
against
pandemic.
This
scoping
review
examined
existing
literature
from
2020
to
2022
on
individual,
interpersonal,
and
structural
barriers
facilitators
vaccination
within
Africa
facilitate
more
informed
health
promotion
interventions
improve
vaccine
uptake.
was
conducted
using
Arksey
O’Malley’s
five-stage
methodological
framework.
A
comprehensive
search
undertaken
2021
six
electronic
databases:
EBSCOhost,
PubMed,
Web
of
Science,
ProQuest,
WorldCat
Discovery,
Google
Scholar.
Data
collected,
charted
into
themes,
summarized
standard
data
extraction
sheet
Microsoft
Excel.
total
forty
(n
=
40)
published
academic
articles
were
reviewed,
with
many
Nigeria
10),
followed
by
Ethiopia
5)
Ghana
4)
rest
elsewhere
Thematic
narratives
used
report
themes:
attitudes
perceptions
about
vaccines,
intention
uptake
vaccines;
factors
associated
uptake;
socio-demographic
determinants
affecting
information
sources
for
vaccines.
ranged
25%
80.9%,
resulting
suboptimal
rate
(54.2%)
African
continent.
Factors
that
promoted
acceptance
included
confidence
vaccines
desire
protect
people.
Age,
education,
gender
most
common
significantly
acceptance.
Most
studies
revealed
considerable
exist
Concerns
potential
side
effects,
ineffectiveness,
perceived
lack
information,
inaccessibility
among
unwillingness
receive
strongly
correlated
being
female.
Mass
social
media
main
regarding
To
encourage
uptake,
governments
should
pay
attention
refuting
misinformation
through
integrated
community-based
approaches,
such
as
creating
messages
convey
than
just
information.
PLOS Global Public Health,
Journal Year:
2024,
Volume and Issue:
4(3), P. e0002986 - e0002986
Published: March 28, 2024
COVID-19
vaccination
rates
have
been
low
among
adults
in
Kenya
(36.7%
as
of
late
March
2023)
with
vaccine
hesitancy
posing
a
threat
to
the
program.
This
study
sought
examine
facilitators
and
barriers
vaccinations
Kenya.
We
conducted
qualitative
cross-sectional
two
purposively
selected
counties
collected
data
through
8
focus
group
discussions
80
community
members
in-depth
interviews
health
care
managers
providers.
The
was
analyzed
using
framework
approach
focusing
on
determinants
their
influence
psychological
constructs.
Barriers
uptake
were
related
individual
characteristics
(males,
younger
age,
perceived
status,
belief
herbal
medicine,
lack
autonomy
decision
making
women
‐
especially
rural
settings),
contextual
influences
(lifting
bans,
myths,
medical
mistrust,
cultural
religious
beliefs),
factors
(fear
unknown
consequences,
side-effects,
understanding
how
vaccines
work
rationale
for
boosters).
However,
volunteers,
trusted
leaders,
mandates,
financial
geographic
access
influenced
uptake.
These
drivers
mainly
constructs
including
confidence,
complacency,
constraints.
Vaccine
is
driven
by
multiple
interconnected
factors.
are
likely
inform
evidence-based
targeted
strategies
that
built
trust
address
hesitancy.
could
include
gender
responsive
immunization
programs,
appropriate
messaging
consistent
communication
target
fear,
safety
concerns,
misconceptions
information
gaps
line
concerns.
There
need
ensure
tested
local
setting
incorporate
multisectoral
leaders
leaders.
Health Security,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 3, 2025
In
this
study,
we
identify
facilitators
and
barriers
to
COVID-19
vaccination
in
Nairobi,
Kenya,
using
the
modified
5
Cs
model
for
vaccine
hesitancy.
We
conducted
33
in-person
interviews
Kenya.
Participants
were
recruited
convenience
sampling
by
a
member
of
research
team
who
resides
Nairobi
speaks
Swahili.
Interviews
audio
recorded
transcripts
analyzed
thematic
analysis.
The
hesitancy
was
applied
create
codebook
prior
cited
misinformation,
lack
trust
science
behind
vaccine,
concerns
about
side
effects
as
reasons
not
receiving
vaccine.
Facilitators
choosing
receive
included
severity
COVID-19,
requirements
school
employment,
communication
from
government.
This
study
is
first
organize
uptake
Kenya
Our
findings
suggest
that
improve
interventions
should
inform
public
vaccine's
safety
reduce
misinformation.
PLOS Global Public Health,
Journal Year:
2022,
Volume and Issue:
2(8), P. e0000917 - e0000917
Published: Aug. 24, 2022
Factors
associated
with
COVID-19
vaccine
hesitancy
(which
we
define
as
refusal
to
be
vaccinated
when
asked,
resulting
in
delayed
or
non-
vaccination)
are
poorly
studied
sub-Saharan
Africa
and
among
refugees,
particularly
Kenya.
Using
survey
data
from
wave
five
(March
June
2021)
of
the
Kenya
Rapid
Response
Phone
Survey
(RRPS),
a
household
representative
population
Kenya,
estimated
self-reported
rates
factors
non-refugees
refugees
Non-refugee
households
were
recruited
through
sampling
2015/16
Household
Budget
random
digit
dialing.
Refugee
registered
refugees.
Binary
response
questions
on
misinformation
information
transformed
into
scale.
We
performed
weighted
(to
overall
Kenya)
multivariable
logistic
regression
including
interactions
for
refugee
status,
main
outcome
being
if
respondent
that
they
would
not
take
available
at
no
cost.
calculated
marginal
effects
various
model.
The
univariate
analysis
18.0%
7.0%
surveyed
offered
Adjusted,
status
was
-13.1[95%CI:-17.5,-8.7]
percentage
point
difference
(ppd)
hesitancy.
For
both
non-refugees,
having
education
beyond
primary
level,
symptoms
COVID-19,
avoiding
handshakes,
washing
hands
more
often
also
reduction
Also
both,
used
internet
past
three
months
8.1[1.4,14.7]
ppd
increase
hesitancy;
disagreeing
government
could
trusted
responding
25.9[14.2,37.5]ppd
There
significant
between
some
variables
(geography,
food
security,
trust
Kenyan
government’s
knowing
somebody
use,
TV
ownership).
These
relationships
certain
suggest
programming
differentiated
specific
contextual
needs
each
group.
Scientific Reports,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: Dec. 23, 2022
The
development
of
effective,
safe,
and
acceptable
vaccines
is
a
long
process.
COVID-19
vaccine
hesitancy
continues
to
elicit
mixed
reactions
among
different
quarters
despite
numerous
evidence
their
effectiveness.
This
study
aimed
determine
the
availability
acceptance
rates
SARS-CoV-2
vaccines,
Kenyan
Hungarian
residing
populations
underlying
reasons
contributing
uptake.
A
non-probability,
snowball
sampling
design
was
employed,
survey
questionnaire
tool
link
expeditiously
disseminated.
Data
were
carefully
analyzed
descriptively.
Demographic
variables,
awareness,
possible
exposure,
associated
with
in
taking
up
vaccine,
choice
other
important
variables
tested
explore
associations
between
two
distinct
countries.
total
1960
participants
successfully
enrolled
research
study,
while
67
excluded
based
on
inclusion
criterion
set.
There
was,
however,
no
significant
difference
public
awareness
Hungarian-residing
participants,
p
=
0.300.
Of
respondents,
62.4%
willing
ready
receive
against
disease.
(p
0.014)
respondents
concerning
uptake
rates.
Hungary
higher
than
Kenya,
mean
0.27,
SD
0.446,
S.
E
0.045
for
population
sample
0.40,
0.492,
0.026,
respectively.
Concerning
gender
acceptance,
there
notable
males
females,
0.001,
where
females
0.29
0.46
Acceptance
females.
functions
One-Way
ANOVA
Chi-square
used
establish
any
differences
means
Concerns
regarding
safety,
efficacy,
accuracy
information
about
developed
are
factors
that
must
be
promptly
addressed,
arrest
crises
revolving
around
hesitancy,
especially
Kenya
both
populations,
lower.
Expansion
screening
program
incorporate
antibody
(serology)
tests,
also
highly
recommended
present
circumstance.
Equitable
distribution
globally
should
encouraged
promoted
adequately
cover
low-
middle-income
To
enhance
effective
combat
vaccination
apprehension
countries,
mitigation
techniques
unique
those
countries
adopted.
Vaccines,
Journal Year:
2023,
Volume and Issue:
11(2), P. 209 - 209
Published: Jan. 17, 2023
Background:
COVID-19
vaccine
uptake
in
Kenya
is
still
low
compared
to
other
countries,
especially
Europe
and
North
America.
In
most
parts
of
the
country,
a
large
percentage
Kenyan
population
remains
unvaccinated.
As
October
2022,
Ministry
Health
(Kenya)
estimates
that
only
36.2%
adult
had
been
fully
vaccinated.
Methods:
We
conducted
an
experimental
study
April
2022
targeting
unvaccinated
adults
who
history
hypertension
and/or
diabetes
those
60+
age
group.
tested
various
messaging
approaches
using
two
different
intervention
channels.
Results:
Although
overall
rate
vaccinated
individuals
according
national
records
low,
responses
from
group
collected
through
phone
call
conversations
show
higher-risk
such
as
older
than
60
or
with
chronic
illnesses
have
remarkably
high
vaccination
89%.
After
study,
four
participants
received
within
1
month
intervention.
These
all
loss-messaging
approach
during
study.
Conclusion:
This
supports
increasing
rates
directed
at
unvaccinated,
high-risk
individuals.
Tropical Medicine and Infectious Disease,
Journal Year:
2023,
Volume and Issue:
8(9), P. 424 - 424
Published: Aug. 24, 2023
COVID-19,
which
was
named
in
March
2020
as
a
global
pandemic
by
the
WHO,
remains
serious
public
health
threat
worldwide.
Despite
adoption
of
vaccines
an
effective
strategy
to
counter
this
pandemic,
vaccination
rate
Cameroon
is
far
lower
than
that
planned
Cameroonian
government
and
its
partners.
The
main
objective
study
determine
factors
limiting
COVID-19
vaccine
acceptance
Menoua
Division
West
Region
Cameroon.
A
community-based
cross-sectional
analytical
conducted
between
April
2022
Division.
pre-tested
questionnaire
filled
out
willing
participants
more
18
years
old,
data
were
further
expressed
order
estimate
knowledge
on
status,
associated
with
refusal.
Pearson
test
performed
identify
factors,
p-value
<
0.05
considered
significant.
total
520
mean
age
33.27
±
12.78
included.
Most
had
secondary
education
level
(56.15%),
trade
informal
sectors
(34.04%)
occupations.
Knowledge
average,
it
significantly
(p
0.05)
gender
level.
10%,
six
times
less
national
target.
lack
information,
confidence,
medicinal
plant
use
all
This
pioneer
identified
knowledge,
leading
Health
authorities
should
therefore
strengthen
sensitization
tackle
information
misinformation
among
target
groups.