Symptomatic COVID-19 in Pregnancy: Hospital Cohort Data between May 2020 and April 2021, Risk Factors and Medicolegal Implications

Diagnostics, Journal Year: 2023, Volume and Issue: 13(6), P. 1009 - 1009

Published: March 7, 2023

Pregnancy does not appear to increase susceptibility SARS-CoV-2 infection, but some physiological changes, such as the reduction of residual functional volumes, elevation diaphragm, and impaired cellular immunity, may risk severe disease result in a higher complications. The article’s primary objective is evaluate factors associated with symptomatic COVID-19 pregnancy. secondary describe maternal neonatal outcomes cases vertical transmission infection. All pregnant women hospitalized SARS-CoV2 infection were included prospective study UOC Obstetrics Gynecology, AOOR Villa Sofia—Cervello, Palermo, between May 2020 April 2021. patients who requested termination pregnancy according Law 194/78 excluded. We 165 pregnancies total number 134 deliveries. Overall, 88.5% asymptomatic at time admission 11.5% symptomatic. Of them, 1.8% required hospital intensive care unit. Symptoms occurrences positively BMI (OR 1.17; p = 0.002), prematurity 4.71; 0.022), lower birth weight 0.99; 0.007). One infant tested positive for nasopharyngeal swab; 11.4% newborns had IgG anti birth; IgM was 2.4% newborns. There no difference statistically significant among group that women.

Language: Английский

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Effectiveness of Psychological Counseling Intervention in High-Risk Pregnancies in Italy

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(9), P. 976 - 976

Published: Sept. 15, 2024

Background: The longitudinal study examines the effectiveness of a psychological support treatment for high-risk pregnancies using between-groups design. It assesses treatment’s impact on depression and fear COVID-19 at three time points, prenatal attachment between 20th 24th weeks gestation (T0), postnatal 15–20 days after birth (T1), months (T2). Additionally, evaluates PTSD related to childbirth parental distress T1 T2. Methods: involved 117 parents experiencing from Sicilian hospital: 84 mothers (40 in experimental group, 44 control group) 33 fathers (19 14 group). Results: ANOVA results showed that was effective maternal variables such as distress, paternal depression, attachment, symptoms, (ANOVA, p < 0.05). Conclusions: highlights growing evidence providing continuous couples with pregnancies, emphasizing this should extend beyond assist families through transition.

Language: Английский

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SARS-CoV-2 Infection and Its Association with Maternal and Fetal Redox Status and Outcomes: A Prospective Clinical Study

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(5), P. 1555 - 1555

Published: Feb. 26, 2025

Background: The impact of the SARS-CoV-2 viral infection during pregnancy on fetus can be direct—transmitted through placenta—and indirect—creating unfavorable conditions for development because inflammation, micro-thrombosis, and hypercoagulation. Our study aimed to determine types frequency pathohistological changes in placental tissue SARS-CoV-2-positive pregnant women examine possible role oxidative stress prognosis delivery its maternal fetal complications. Methods: This prospective clinical included 50 divided into two groups, positive (COVID-19 group) negative (control group), from who we collected demographic, clinical, obstetric, biochemical pathologic data. Data about newborn characteristics were also collected, which anamnestic, Results: values superoxide anion radical index lipid peroxidation significantly different mothers concerning presence infection, while levels nitric oxide, peroxidation, reduced glutathione, dismutase newborns depending infection. Newborn similar between groups except concentrations IgM antibody. incidence FVM type COVID-19 group was 46%, control group, 18%. Conclusions: confirmed significant parameters stress-mediated dysfunction. Future studies should performed with more participants follow-up neonatal development.

Language: Английский

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Half of the mothers had poor delivery referral practices in public hospitals of Bahir Dar City Northwest, Ethiopia

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 26, 2025

Policy makers and stakeholders may benefit from understanding maternal delivery referral practices as they develop efficient mechanisms to implement appropriate linkage. However, the practice of is not well known. This study aims assess associated factors among laboring mothers referred public hospitals Bahir Dar City, Northwest, Ethiopia. In city Dar, a facility-based cross-sectional survey was carried out March 1 30, 2021. A total 358 who came by give birth at in were interviewed using pre-tested questionnaire that presented an interviewer. Data coded, inputted Epi-data version 3.1 software, after being transferred, analyzed SPSS 25. The linked poor identified bi-variable multivariable logistic regressions. p-value cutoff 0.05 ultimately determined be statistically significant. 353 participants took part study. level 52.7% (95% CI 47%, 58%). mean age respondents 26.73 (± 5.45) years. Twenty eight percent illiterate. Unable read write (AOR = 2.38, 95%CI: 1.15, 4.94), only 6.59, 2.53, 17.17), monthly income < 1,527 birr 4.55, 1.91, 10.84), between 3,000 4.29, 1.76, 10.50), 3,001 5,305 3.73, 1.49, 9.33), 4.63, 1.94, 11.07), gave via cesarean section 2.06, 1.22, 3.47), assisted 4.77, 1.64, 13.91), time spent more than h arrive City 2.15, 1.07, 4.34) significantly with practice. Poor widespread. use referrals influenced obstetric, social, environmental, demographic factors. during labor should receive most attention have low incomes do attend formal education.

Language: Английский

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Long-Term Effects of COVID-19 on Women’s Reproductive Health and Its Association with Autoimmune Diseases, Including Multiple Sclerosis

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(9), P. 3057 - 3057

Published: April 29, 2025

Concern over COVID-19’s long-term influence on women’s reproductive health is growing, with emerging research suggesting potential links to ovarian dysfunction, menstrual irregularities, fertility challenges, and adverse pregnancy outcomes. Post-viral immune dysregulation linked both the development exacerbation of autoimmune diseases, including multiple sclerosis (MS). Long COVID has been associated immunological hormonal imbalances, chronic inflammation, all which may worsen disorders issues. characterized by symptoms persisting for weeks or months beyond acute infection phase. There are indications that prolonged contribute disease through mechanisms such as hyperactivation, molecular mimicry, dysregulated cytokine responses. Although this field still emerging, growing evidence suggests SARS-CoV-2 have lasting effects health, highlighting need further studies into its underlying clinical This review compiles recent findings impact COVID-19 association disorders, particularly MS.

Language: Английский

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Effects of the combination of exercise and education in the treatment of low back and/or pelvic pain in pregnant women: Systematic review and meta‐analysis

International Journal of Gynecology & Obstetrics, Journal Year: 2023, Volume and Issue: 164(3), P. 811 - 822

Published: July 21, 2023

Abstract Background Lumbopelvic pain is considered the most frequent complication during pregnancy. Objective To compare whether combination of exercise with education more effective for treatment low back and/or pelvic (PP) than each these interventions separately in pregnant women. Search Strategy A systematic review was performed WOS, PEDro, PubMed, Cochrane, and ClinicalTrials.gov . The terms used were pain, PP, pregnancy, woman, exercise, therapy, health education, prenatal education. Selection Criteria PICO question then chosen as follows: P—population: women nonspecific or PP; I—intervention: therapy plus education; C—control: only O—outcome: characteristics disability, kinesophobia; S—study designs: randomized controlled trial. Data Collection Analysis Two reviewers independently screened articles eligibility. following inclusion criteria applied selection studies: (i) published past 10 years; (ii) administered compared a group receiving either alone; (iii) sample consisted PP. This excluded: nonrandomized trials; whose full text not available. meta‐analysis using random‐effects model, due to observed heterogeneity. Main Results total 13 selected. There significant decrease alone (standardized mean difference, −0.29 [95% confidence interval, −0.47 −0.11]). With respect there that addressed −0.37 CI, −0.60 −0.14]). One article analyzed kinesophobia, reporting no changes. Conclusion seems be reducing disability PP use alone. In results found are significant.

Language: Английский

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COVID-19 Vaccination Acceptance During Pregnancy in Europe

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: July 1, 2024

Pregnant women have been shown to a higher risk of SARS-CoV-2 infection. Vaccination against the infection is most effective strategy for preventing both severe disease and related complications. Nevertheless, vaccination hesitancy among pregnant an important issue affecting vaccine uptake major challenge Public Health, as high rates can lead complete refusal vaccination, with health implications not only mother but also fetus. Based on above, this review aims capture COVID-19 in pregnancy European countries, from August 2020 May 2022, well highlight predictive factors its acceptance these countries. The available literature found that Europe varies ranging 21.3% 87% at least one dose 29.5% 82.7%, two doses vaccine. Higher maternal education level, older age pregnancy, previous influenza pertussis, positive attitude towards vaccines, vaccines during are frequently reported predictors associated rates. information obtained study contribute future, epidemics or pandemics may occur, development targeted medical communication strategies promotion programs greatest possible coverage population, especially those belonging vulnerable groups such women.

Language: Английский

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A Meta-Analysis of the Global Stillbirth Rates during the COVID-19 Pandemic

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(23), P. 7219 - 7219

Published: Nov. 21, 2023

COVID-19 has been shown to have variable adverse effects on pregnancy. Reported data stillbirth rates during the pandemic have, however, inconsistent—some reporting a rise and others no change. Knowing precise impact of stillbirths should help with planning delivery antenatal care. Our aim was, therefore, undertake meta-analysis determine rate. Databases searched included PubMed, Embase, Cochrane Library, ClinicalTrials.gov, Web Science, language restriction. Publications women COVID-19, comparing in non-COVID-19 women, as well comparisons before pandemic, were included. Two independent reviewers extracted separately then compared them ensure accuracy extraction synthesis. Where incomplete, authors contacted for additional information, which was if provided. The main outcome measures (1) (SB) rate pregnant (2) without same period, (3) population pre-pandemic periods. A total 29 studies meta-analysis; from 17 these, SB 7 per 1000 COVID-19. This much higher (34/1000) low- middle-income countries. odds ratio 1.89. However, there significant difference between Stillbirths are an ongoing global concern, is evidence that increased but mostly major factor this possibly access healthcare pandemic. Attention be focused education provision high-quality maternity care, such face-to-face consultation (taking all preventative precautions) or remote appointments where appropriate.

Language: Английский

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Maternal and Fetal Outcomes of COVID-19 According to the Trimester of Diagnosis: A Cross-Sectional Prospective Study in a Tertiary University Hospital

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(17), P. 5262 - 5262

Published: Sept. 5, 2024

Pregnant women are considered a high-risk group because they may be particularly susceptible to COVID-19. Our study tried relate fetomaternal outcomes and trimester-specific infection.

Language: Английский

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Risk Factors for Severe–Critical COVID-19 in Pregnant Women

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(18), P. 5812 - 5812

Published: Sept. 7, 2023

Risk factors associated with severe-critical COVID-19 (coronavirus disease 2019) are based on findings in the general population. Pregnant women at increased risk of infection, and few reports these women. A multicentric case-control study was conducted Mexican Institute Social Security, State Mexico, during pandemic. We included pregnant who were consecutively admitted to respiratory care units followed until 30 days after resolution pregnancy. total 758 a positive RT-PCR test for SARS-CoV-2 enrolled from June 2020 July 2021. defined groups using World Health Organization Severity Classification; cases (n = 123), controls subjects non-severe 635). Data gathered clinical files. multivariate logistic regression analysis used adjust odds ratios their 95% confidence intervals COVID-19. pregnancy non-vaccination (OR 10.18), blood type other than O 6.29), maternal age > 35 years 5.76), history chronic hypertension 5.12), gestational infection ≥ 31 weeks 3.28), multiparity 2.80).

Language: Английский

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