Metabolites,
Journal Year:
2024,
Volume and Issue:
14(12), P. 713 - 713
Published: Dec. 18, 2024
Background:
The
gut
microbiota
are
an
important
interface
between
the
host
and
environment,
mediating
host’s
interactions
with
nutritive
non-nutritive
substances.
Dietary
contaminants
like
Bisphenol
A
(BPA)
may
disrupt
microbial
community,
leaving
susceptible
to
additional
exposures
pathogens.
BPA
has
long
been
a
controversial
well-studied
contaminant,
so
its
structural
analogues
S
(BPS)
replacing
it
in
consumer
products,
but
have
not
well
studied.
Methods:
This
study
aimed
determine
impact
of
BPS
on
C57BL/6
murine
using
shotgun
metagenomic
sequencing
metabolomic
profiling
vitro
anaerobic
cultures.
Results:
results
demonstrated
that
supraphysiologic
dose
did
overtly
distort
or
profiles
exposed
cultures
compared
controls.
distinct
BPS-associated
metabolite
profile
was
observed,
several
metabolites,
including
saturated
fatty
acids,
were
enriched
BPS-exposed
In
absence
enterotype,
Lactobacillus
species
specifically
associated
exposure
discriminant
model.
Conclusions:
Our
provides
evidence
contrasting
effects
microbiome
predecessor,
BPA,
also
emphasizes
role
inter-animal
variation
composition,
indicating
further
is
needed
characterize
this
context.
Tropical Aquatic and Soil Pollution,
Journal Year:
2023,
Volume and Issue:
3(2), P. 131 - 143
Published: July 12, 2023
Bisphenol
A
(BPA)
is
recognized
as
an
endocrine
disruptor,
capable
of
interfering
with
the
normal
functioning
hormones
within
body
by
mimicking
effects
estrogen.
Drinking
water
one
most
common
pathways
exposure
to
BPA
it
can
permeate
plastic
products
and
other
materials,
entering
sources.
This
article
presents
a
comprehensive
overview
BPA,
including
its
incidence,
origins,
environmental
fate,
impact
on
human
health,
role
fungi
in
biodegradation
BPA.
Fungi
are
natural
decomposers,
breaking
down
organic
compounds,
under
suitable
conditions.
Studies
have
demonstrated
that
specific
species
effectively
biodegrade
Some
utilize
ligninolytic
enzymes,
such
laccases
peroxidases,
break
phenolic
rings
Other
employ
non-ligninolytic
esterases
hydrolases,
cleave
ester
linkages
Furthermore,
some
via
cometabolic
pathways,
whereby
chemical
degraded
side
reaction
degradation
another
substrate.
The
use
immobilized
enzymes
for
has
also
potential.
Immobilized
those
attached
solid
support,
polymer
or
matrix,
allowing
them
be
used
multiple
times
enhance
their
stability
catalytic
activity
UTTAR PRADESH JOURNAL OF ZOOLOGY,
Journal Year:
2024,
Volume and Issue:
45(12), P. 114 - 124
Published: May 21, 2024
Background:
Bisphenol
A
(BPA),
is
an
organic
component,
functions
as
endocrine
disruptor
(EDC).
It
ubiquitously
exists
in
both,
the
environment
and
food
sources,
leading
to
continuous
unintentional
exposure
among
populations
of
human
animal.
Aim
Study:
Investigate
biodegradation
activity
BPA
by
bacteria
isolated
from
polluted
soil
with
plastic
wastes.
Materials
Methods:
50
samples
were
taken
wastes
different
sites
Kerbala
province;
minimal
salt
media
(MSM)
used
identify
capability
isolates
bioremediate
200
mg/L,
a
final
concentration
using
HPLC
analysis.
Results:
bacterial
could
degrade
ranges
started
18.7%
99.9%.
recent
study
found
that,
Serratia
plymuthica,
Pantoea
spp,
Shingomonas
paucimobilis,
Pseudomonas
aeruginosa
Bacillus
spp.
more
efficient
than
Acinetobacter
haemolyticus,
lwoffii,
Escherichia
coli
Proteus
Conclusion:
Many
types
convert
toxic
compound
another
metabolites
according
we
employee
these
eliminate
materials
safely
soils
water
efficiently
chemicals
that
might
be
environment,
being
animals.
Ecotoxicology and Environmental Safety,
Journal Year:
2024,
Volume and Issue:
280, P. 116564 - 116564
Published: June 11, 2024
Natural
estrogens,
including
estrone
(E1),
17β-estradiol
(E2),
and
estriol
(E3),
are
potentially
carcinogenic
pollutants
commonly
found
in
water
soil
environments.
Bacterial
metabolic
pathway
of
E2
has
been
studied;
however,
the
catabolic
products
E3
have
not
discovered
thus
far.
In
this
study,
Novosphingobium
sp.
ES2-1
was
used
as
target
strain
to
investigate
its
E3.
The
metabolites
were
identified
by
high
performance
liquid
chromatography-high
resolution
mass
spectrometry
(HPLC-HRMS)
combined
with
stable
Critical Reviews in Environmental Science and Technology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 25
Published: Nov. 20, 2024
Bisphenol
A
(BPA)
is
an
emerging
contaminant
that
disrupts
endocrine
systems
and
poses
significant
risks
to
organisms.
It
increasingly
detected
in
municipal
wastewater
due
its
widespread
use
high
production
volume.
Despite
this,
gaps
remain
understanding
the
sources
of
BPA
wastewater,
effects
on
nitrification
denitrification,
potential
for
co-removal
with
ammonia
or
nitrate
during
biological
nitrogen
removal
processes.
This
review
first
examines
BPA,
primarily
from
industrial
effluents
landfill
leachates,
which
enter
treatment
plants
alongside
domestic
sewage.
Additionally,
it
meticulously
elucidated
influences,
performance,
biotransformation
mechanisms
denitrification
processes,
shedding
light
pathways,
functional
microbes
key
enzymes.
While
there
no
consensus
anoxic
conditions,
aerobic
environments
support
biodegradation
through
various
microorganisms.
Lastly,
microbial
cooperation
enhance
discussed,
focusing
bacterial
mutual
alliances
bacteria-algae
metabolic
interaction
consortiums.
provides
valuable
guidance
synergistic
