Optimal extent of lymph node dissection in clinical early-stage right colon cancer: a retrospective analysis

Annals of Surgical Treatment and Research, Journal Year: 2025, Volume and Issue: 108(1), P. 49 - 49

Published: Jan. 1, 2025

Determining the extent of radical lymphadenectomy at clinical early stage is challenging. We aimed to investigate appropriate in early-stage right colon cancer. Patients with 0 or I cancer who underwent curative surgery from January 2007 December 2021 were included this retrospective study. The lymph node (LN) metastases based on distribution LN (LND: LND1 pericolic nodes, LND2 intermediate LND3 apical nodes), along depth submucosal (SM) invasion (classed into SM1-3), analyzed. Of 348 patients, across pathologic stages was as follows: 30 patients (8.6%) 0, 207 (59.5%) I, 52 (14.9%) II, and 59 (17.0%) III. In pT1 tumor varied by SM depth: 3.6% SM1 (all LND1), 5.1% SM2 17.5% SM3 (LND1 10%, 5%, 2.5%). For pT2, pT3, pT4 stages, metastasis rates 16.2% 11.3%, 3.8%, 1.3%), 39.7% 28.9%, 8.4%, 2.4%), 50% 25%, 25%), respectively. Tumor lymphovascular identified significant risk factors for extending LND2-3. Complete mesocolic excision should be considered right-sided because infiltration deeper than could metastasize further. If preoperative endoscopy confirms invasion, D2 a limited surgical option.

Language: Английский

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Effects of Microsatellite Instability on the Clinical and Pathological Characteristics of Colon Cancer and the Diagnostic Accuracy of Preoperative Abdominal CT Scans

Diagnostics, Journal Year: 2025, Volume and Issue: 15(2), P. 190 - 190

Published: Jan. 15, 2025

Background: Microsatellite-stable (MSS) and microsatellite-instable (MSI) colon cancer (CC) cases have different characteristics. These characteristics may impact the accuracy of abdominal computed tomography (CT) scan examinations in MSI CC. Methods: A retrospective analysis was conducted to examine effects CC on patients’ clinical tumor We determined radiological T N staging compared pathological patients evaluated influence tumor- patient-related factors this accuracy. Results: total 131 who had undergone surgical resection were analyzed. Mismatch repair-deficient (dMMR) predominantly found right hemicolon (p = 0.023); it more likely exhibit moderate (80.8%) or low-grade differentiation 0.01) higher rates mucinous 0.001). The median neutrophil platelet counts C-reactive protein (CRP) levels at diagnosis significantly with dMMR 0.022, p 0.018). depth invasion influenced CRP 0.015). CT exam accurate regarding colonic wall 58.1% 38.5% mismatch repair-proficient (pMMR) CC, respectively. assessment lymph node 44.8% those pMMR 50.0% There no significant difference predicting statuses between two groups. determination not affected by parameters examined. Conclusions: has specific characteristic features. does affect preoperative CT.

Language: Английский

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The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases

Turkish Journal of Clinics and Laboratory, Journal Year: 2025, Volume and Issue: 16(1), P. 27 - 33

Published: March 25, 2025

Aim: This study aims to assess the diagnostic accuracy of multi-slice computed tomography (CT) colonography in detecting colorectal lesions. Material and Methods: 22 patients with confirmed or clinically suspected pathology underwent CT followed by conventional colonoscopy on same day. The findings were compared those obtained from colonoscopy. Results: Of who colonography, 10 (45%) evaluated as normal. Bowel wall thickening was observed 4 (18%), while polypoid lesions detected 8 (36%). Among 9 identified through colonoscopy, also colonography. overall sensitivity for lesions, regardless size, 89%. Sensitivity 50% smaller than 1 cm 100% larger cm. When according their histology, Colonography found be tubular adenoma, tubulovillous adenocarcinoma. Conclusion: These results indicate that is a valuable modality comprehensive evaluation colon. represents viable alternative traditional cancer screening methods due its high coupled relatively safe minimally invasive nature.

Language: Английский

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Effect of Fluorescence Lymph Node Mapping on Improving Diagnostic Values of CT D3 Lymph Node Staging for Right-Sided Colon Cancer

Cancers, Journal Year: 2024, Volume and Issue: 16(20), P. 3496 - 3496

Published: Oct. 16, 2024

This study evaluated the impact of fluorescence lymph node mapping (FLNM) using indocyanine green (ICG) on diagnostic accuracy preoperative computed tomography (CT) in right-sided colon cancer.

Language: Английский

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Nuclear medicine based multimodal molecular imaging facilitates precision medicine for gastrointestinal tumors

Shijie huaren xiaohua zazhi, Journal Year: 2024, Volume and Issue: 32(10), P. 727 - 734

Published: Oct. 28, 2024

Language: Английский

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2023 Korean Multidisciplinary Guidelines for Colon Cancer Management: Summary of Radiological Points

Korean Journal of Radiology, Journal Year: 2024, Volume and Issue: 25(9), P. 769 - 769

Published: Jan. 1, 2024

Language: Английский

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