Seaweed Proteins: A Step towards Sustainability?

Nutrients, Journal Year: 2024, Volume and Issue: 16(8), P. 1123 - 1123

Published: April 10, 2024

This review delves into the burgeoning field of seaweed proteins as promising alternative sources protein. With global demand escalating and concerns over traditional protein sources' sustainability ethics, emerges a viable solution, offering high content minimal environmental impacts. Exploring nutritional composition, extraction methods, functional properties, potential health benefits proteins, this provides comprehensive understanding. Seaweed contains essential amino acids, vitamins, minerals, antioxidants. Its ranges from 11% to 32% dry weight, making it valuable for diverse dietary preferences, including vegetarian vegan diets. Furthermore, underscores advantages production compared sources. cultivation requires resources, mitigating issues like ocean acidification. As specific types, methodologies, highlights versatility in various food products, plant-based meats, dairy alternatives, supplements. Additionally, discusses associated with such their unique acid profile bioactive compounds. Overall, aims provide insights proteins' applications role addressing needs sustainably.

Language: Английский

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Immunomodulatory Compounds from the Sea: From the Origins to a Modern Marine Pharmacopoeia

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(7), P. 304 - 304

Published: June 28, 2024

From sea shores to the abysses of deep ocean, marine ecosystems have provided humanity with valuable medicinal resources. The use organisms is discussed in ancient pharmacopoeias different times and geographic regions still deeply rooted traditional medicine. Thanks present-day, large-scale bioprospecting rigorous screening for bioactive metabolites, ocean coming back as an untapped resource natural compounds therapeutic potential. This renewed interest drugs propelled by a burgeoning research field investigating molecular mechanisms which newly identified intervene pathophysiology human diseases. Of great clinical relevance are molecules endowed anti-inflammatory immunomodulatory properties emerging applications management chronic inflammatory disorders, autoimmune diseases, cancer. Here, we review historical development pharmacology Eastern Western worlds describe status drug discovery. Finally, discuss importance conducting sustainable exploitation resources through biotechnology.

Language: Английский

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Bioactivities related to pigments content of Sargassum sp. Collected from Jeddah coast, Saudi Arabia, Red Sea

The Egyptian Journal of Aquatic Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

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Unravelling the benefits of nutraceutical seaweed <i>Ecklonia</i> to reaping its pharmaceutical approaches

Natural Resources for Human Health, Journal Year: 2025, Volume and Issue: 5(2), P. 245 - 254

Published: April 7, 2025

Growing concern for human health has driven researchers worldwide to reap the benefits of marine algal species due their potent, multifaceted nature and bioactivity. These are nutritionally dense sources bioactive compounds with distinct properties. The seawater ecosystem is a treasury secondary higher therapeutic potential diverse uniqueness, like phlorotannin halo compounds. Several studies have highlighted molecules obtained from one brown algae, <i>Ecklonia</i>, which can reduce activities key regulators TNF-a, NF-kB, MAPKs. Hence, step forward in our current study, we comprehend function <i>Ecklonia</i> disease models, including Alzheimer’s, coronary artery Type 2 Diabetes, by utilizing Network Pharmacology approach. This method integrates bioinformatics, systems biology, pharmacology understand complex interactions between biological systems. Our possible compound significant genes HMGCR, PTGS2, ADRB2, AURKA, PDE4D, were identified as targets importance drug development design pharmaceutical industries.

Language: Английский

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Encapsulation of Phloroglucinol from Rosenvingea intricata Macroalgae with Zinc Oxide Nanoparticles against A549 Lung Cancer Cells

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(10), P. 1300 - 1300

Published: Oct. 5, 2024

Background/Objectives: Phloroglucinol (PHL), a phenolic compound extracted from the brown alga Rosenvingea intricata, exhibits potent antioxidant and anticancer properties. This study aims to extract, purify, characterize PHL, further develop functionalized zinc oxide nanoparticles (ZnO NPs) loaded with PHL enhance its therapeutic potential. Methods: was using acetone purified through Sephadex LH-20 column chromatography, yielding highly enriched fraction (F-3). The characterized by FTIR, HPLC, NMR, LC-MS. ZnO NPs were synthesized, PEGylated, conjugated forming ZnO-PEG-PHL NPs. Their characterization included DLS, zeta potential, XRD, SEM-EDAX, encapsulation efficiency studies. Antioxidant assays (DPPH, FRAP, ABTS, RPA) performed in vitro cytotoxicity on A549 lung cancer cells determined evaluate efficacy of PHL. Results: showed high content (45.65 mg/g), which confirmed spectral analysis. increased size 32.36 nm 46.68 nm, their potential shifting −37.87 mV −26.82 mV. activity superior for all assays, while tests an IC50 40 µg/mL compared 60 70 Apoptotic studies revealed significant cell cycle arrest apoptosis induction. Conclusions: synthesized demonstrated enhanced properties, making them promising candidates therapy applications.

Language: Английский

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Red Algae Compounds: Potential Neuroprotective Agents for Neurodegenerative Disorders

OBM Neurobiology, Journal Year: 2024, Volume and Issue: 08(02), P. 1 - 27

Published: May 10, 2024

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar carrageenans, stand out predominant widely utilized algae. Additionally, harbor a spectrum molecules such essential fatty acids, phycobiliproteins, vitamins, minerals, secondary metabolites. Extensive research has highlighted biological activities exhibited by these compounds, including anti-oxidative anti-inflammatory properties. These show various that have garnered interest their therapeutic diseases. comprehensive aims to summarize current knowledge regarding extraction, characterization, mechanisms action, applications Rhodophyta-derived context neuroprotection treatment

Language: Английский

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Isolation, Characterization, Antimicrobial Properties, and Theoretical Investigations of a New Isoflavanol from Nigerian Red Propolis for Therapeutic Applications

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1318, P. 139203 - 139203

Published: July 17, 2024

Language: Английский

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