Zeitschrift für Gastroenterologie,
Journal Year:
2023,
Volume and Issue:
61(07), P. 955 - 956
Published: July 1, 2023
Dieser
Fall
soll
die
Aufmerksamkeit
auf
klinische
Diagnose
einer
Dysphagie
und
den
endoskopischen
Befund
Hyperkeratose
lenken.
Ein
75-jähriger
Patient
wurde
im
Juli
2020
wegen
Dysphagie,
Globusgefühl,
Regurgitation
Erbrechen
stationär
aufgenommen.
Die
Gastroskopie
zeigte
eine
Ringstruktur
Kreppmukosa
Ösophagus.
Schleimhaut
war
vulnerabel
das
Endoskop
konnte
letzten
Ösophagusdrittel
nicht
weiter
vorgeschoben
werden.
Revista Española de Enfermedades Digestivas,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Esophageal
lichen
planus
(ELP)
is
a
rare
chronic
inflammatory
condition
with
delayed
diagnosis
that
can
present
dysphagia.
It
has
been
scarcely
studied
in
the
literature,
and
clinical
management
guidelines
are
lacking.
Stenosis
neoplastic
transformation
among
its
most
feared
complications.
We
fifth
reported
case
of
ELP
to
be
successfully
treated
Upadacitinib.
Zeitschrift für Gastroenterologie,
Journal Year:
2024,
Volume and Issue:
62(09), P. 1384 - 1388
Published: June 25, 2024
As
of
now,
there
exists
no
established
therapy
for
ELP.
Retinoids,
which
are
standard
in
treating
cutaneous
LP,
do
not
exhibit
positive
effects
While
topical
glucocorticosteroids
often
yield
favorable
responses
esophageal
inflammation,
some
cases
prove
recalcitrant
or
refractory.
In
such
instances,
various
immunosuppressive
therapies
have
been
attempted
with
variable
success.This
report
details
a
severe
case
ELP
that
showed
resistance
to
prednisolone,
acitretin,
alitretinoin,
adalimumab,
tacrolimus,
hydroxychloroquine
plus
mycophenolate
mofetil,
and
cyclophosphamide.
The
initiation
the
JAK
inhibitor
tofacitinib
induced
an
impressive
clinical,
endoscopic,
histological
remission.
This
response
is
discussed
context
our
evolving
understanding
immune-mediated
pathogenesis
this
disease.
The American Journal of Gastroenterology,
Journal Year:
2024,
Volume and Issue:
119(12), P. 2376 - 2388
Published: Aug. 21, 2024
Esophageal
squamous
cell
carcinoma
(ESCC)
remains
the
most
common
malignancy
of
esophagus
worldwide.
Environmental
and
lifestyle
exposures
such
as
alcohol
tobacco
have
been
well
defined
in
pathogenesis
ESCC,
acting
concert
with
intrinsic
epigenomic,
genomic
transcriptomic
changes.
However,
a
variety
nonenvironmental
etiologies
including
Fanconi
anemia,
lichen
planus,
chronic
mucocutaneous
candidiasis,
esophageal
epidermoid
metaplasia,
epidermolysis
bullosa,
tylosis,
atresia,
achalasia
receive
minimal
attention
despite
high
risk
ESCC
these
diseases.
The
goal
this
review
was
to
promote
clinical
recognition
suggest
diagnostic
framework
for
earlier
detection
patients
rare
In
all
discussed
conditions,
change
symptoms
should
trigger
prompt
endoscopic
evaluation,
surveillance
programs
advanced
imaging
techniques
chromoendoscopy
be
considered.
Moreover,
we
leverage
convergence
diseases
on
identify
mechanisms
underlying
malignant
transformation
aberrant
proliferation,
mucosal
barrier
dysfunction,
increased
inflammation,
genome
instability.
study,
summarize
presentation,
pathologic
findings,
potential
screening
strategies,
associated
that
drive
ESCC.
Expert Review of Gastroenterology & Hepatology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 13, 2024
Lymphocyte-rich
inflammation
of
the
esophageal
mucosa
has
gained
increased
awareness
among
pathologists
and
clinicians
recently.
Patients
usually
present
with
symptoms
dysfunction,
including
dysphagia
food
bolus
impaction.
Endoscopy
may
show
changes
similar
to
eosinophilic
esophagitis
but
also
be
entirely
normal
('microscopic
esophagitis').
Three
morphological
subtypes
or
variant
forms
have
been
described
which
include
lymphocytic,
lichenoid
lymphocyte-predominant
esophagitis.
These
need
discriminated
against
other
distinct
causes
lymphocytosis,
such
as
gastro-esophageal
reflux
disease
Candida
infection.
