Frontiers in Aging Neuroscience, Journal Year: 2024, Volume and Issue: 16
Published: Sept. 4, 2024
This study points to probing the inclination and mapping knowledge domain of acupuncture for Parkinson's disease through bibliometrics.
Language: Английский
BMC Gastroenterology, Journal Year: 2024, Volume and Issue: 24(1)
Published: Sept. 5, 2024
Language: Английский
Citations
6
Hepatology International, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 16, 2024
Abstract Background The international consensus to revise non-alcoholic fatty liver disease metabolic (dysfunction)-associated (MAFLD) in 2020 attracted significant attention. impact of the MAFLD definition on research community has not been objectively assessed. We conducted an analysis systematically collected literature understand its impact. Methods From PubMed, Web Science, and Scopus, adopting MAFLD, written English, published from 10 October 2023 was collected. publication metrics, including counts, publishing journals, author countries, keywords, citation information, were analyzed evaluate key topics MAFLD. Results 1469 MAFLD-related papers 434 journals with a steady increase number. intense citations activity indicates large redefinition. Topic assessment keyword revealed transition proposal discussion redefinition clinical characterization focus dysfunction. Moreover, diagnostic criteria for showed better performance predicting hepatic extrahepatic outcomes compared NAFLD. publications 99 countries evidence strong regional global collaboration. Multiple societies stakeholders have endorsed utility practice, improving patient management promoting multidisciplinary care, while alleviating stigma. Conclusion This survey provides quantitative measure considerable contributions towards as part spectrum cardiometabolic disorders.
Language: Английский
Citations
4
Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: Jan. 2, 2025
This study investigated the association between NAFLD and liver fibrosis ratio of gamma-glutamyl transferase to high-density lipoprotein cholesterol (GGT/HDL-C). In this cross-sectional study, we included 4764 subjects who participated in National Health Nutrition Examination Survey (NHANES) during 2017–2018. Adjusted multivariate logistic regression analysis was utilized evaluate relationships GGT/HDL-C levels NAFLD, fatty degree, fibrosis. The non-linear link examined using generalized additive models. There a risk all models demonstrated strong relationship fibrosis, degree hepatic steatosis, prevalence NAFLD. Subgroup analyses revealed significant correlation among Mexican Americans young people 20–40 age range. receiver operating characteristic (ROC) showed that more accurate predictor than GGT or HDL-C alone. U.S. population, an increased severity are independently correlated with elevated ratio.
Language: Английский
Citations
0
Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 15
Published: Jan. 7, 2025
To explore the current research status and trends of potassium-competitive acid blockers (P-CABs) in treatment related diseases (ARDs) using bibliometric analysis. We collected publications to P-CAB acid-related Web Science (WOS) Core Collection from establishment database 30 June 2024. evaluated publication volume citation over years WOS platform, visualized authors, countries, institutions, keywords, citations CiteSpace VOSviewer. This study included a total 455 articles. The number has been increasing year by year. results show that scholars with highest mainly come South Korea Japan. Scholars such as Geun Seog Song, Bongtae Kim, Nobuhiro Inatomi produced many works fields. most popular drug this field was vonoprazan, on focused effectiveness safety evaluation ARDs Helicobacter pylori infection, gastroesophageal reflux disease, peptic ulcers, etc. Researchers were concerned about regimens efficacy comparison between P-CABs traditional proton pump inhibitors (PPIs) ARDs. At same time, researchers are also closely monitoring potential adverse reactions long-term outcomes clinical application for P-CABs, represented is receiving widespread attention researchers. exploration type constantly expanding, it great value potential.
Language: Английский
Citations
0
Saudi Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Abstract Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) presents a significant global health challenge, with the Arab region exhibiting markedly higher prevalence. We aim to evaluate MASLD research output, collaboration patterns, and funding impact in over last decade. Methods: conducted bibliometric analysis of 22 countries (2014–2023) using Clarivate Analytics’ InCites. Data on prevalence were extracted from Global Burden Disease, while population economic data World Bank. assessed MASLD-related publications, prevalence, citation impact. Results: Between 2014 2023, contributed 844 publications (3.3% research). identified positive correlations between gross domestic product (GDP) ( r s = 0.825, P < 0.001), age-standardized 0.627, 0.002), size 0.509, 0.016). International collaborations accounted for 48.7% these 15.7 compared average 23.7. Arab-funded constituted 19.4% world versus 42.3% globally funded. Citation impacts similar (30.6) funded (30.3). Of top 10 highest GDP, 47.8% received funding, yielding 33.5. Conclusion: Despite high exhibit lower impact, levels. Increased regional investment are critical addressing this disparity.
Language: Английский
Citations
0
Phytotherapy Research, Journal Year: 2025, Volume and Issue: unknown
Published: April 4, 2025
It is widely recognized that there currently no established treatment for individuals with Non-alcoholic Fatty Liver Disease (NAFLD). In recent years, has been a surge of interest in natural products derived from plants, driven by their minimal toxicity and notable efficacy. was reported could ameliorate NAFLD via various mechanisms. On the other hand, autophagy suggested to be involved pathogenesis NAFLD. The aim this review understand whether beneficial effects on are mediated affecting pathways. review, we have compiled data elucidating how these exhibit potential improve modulating core autophagic Specifically, demonstrate products, including resveratrol, berberine, curcumin, quercetin, punicalagin, epigallocatechin-3-gallate, apigenin, many others, regulate through key signaling pathways, such as AMPK/SIRT1/mTOR. Interestingly, compounds might activate or inhibit autophagy, depending context. We explore activation promotes degradation lipid droplets alleviates liver injury, while inhibition contributes reducing inflammation, apoptosis, pyroptosis, also resulting improved outcomes. Taken together, findings suggest targeting presents promising mechanism preventing treating
Language: Английский
Citations
0
Frontiers in Pediatrics, Journal Year: 2025, Volume and Issue: 13
Published: April 28, 2025
Background Metabolic dysfunction-associated steatotic liver disease (MASLD), once known as Non-alcoholic fatty disease, impacts between 3% and 10% of children adolescents globally, well nearly one-third obsessed boys one-quarter girls, is the most frequent cause pediatric associated with obesity epidemic. With growing attention increasing volume literature on MASLD, there an urgent need for bibliometric analysis visualization in area MASLD study terms dissecting priorities. Methods Literature was searched Web Science Core Collection database, followed by categorization, visual conducted applying software including Citespace, VOSviewer, R language. The concentrated analyzing information related to key authors, spatial temporal distribution, core keywords, important citations. Results In total, 3,409 publications were collected study, 2,697 articles 712 review articles. Between 2004 2024, had been constantly per year. country numerous United States, which extensive exchanges collaborations Italy, China, England, Italy. Journal Pediatric Gastroenterology Nutrition greatest quantity this domain. a clinical guideline. Insulin resistance, metabolic syndrome, steatohepatitis, hepatocellular carcinoma, cardiovascular risk, diabetes diagnostic accuracy, lifestyle intervention, gut microbiome, probiotics, also hot topics frontier trends studies. Conclusion This research represents inaugural application examine developmental trajectory studies over past two decades, reveals that etiology, pathological changes liver, relationship obesity, complications, comorbidities, diagnosis treatments are focuses provides academic references clinicians scholars grasp hotspots, cutting edge evolving area.
Language: Английский
Citations
0
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(9), P. 4256 - 4256
Published: April 30, 2025
Metabolic-dysfunction-associated steatotic liver disease (MASLD) has emerged as a significant public health concern, attributed to its increasing prevalence and correlation with metabolic disorders, including obesity type 2 diabetes. Recent research highlighted that mitochondrial dysfunction can result in the accumulation of lipids non-adipose tissues, well increased oxidative stress inflammation. These factors are crucial advancing progression MASLD. Despite advances understanding MASLD pathophysiology, challenges remain identifying effective therapeutic strategies targeting dysfunction. This review aims consolidate current knowledge on how imbalance affects development MASLD, while addressing existing gaps potential avenues for future research. was conducted after systematic search comprehensive academic databases such PubMed, Embase, Web Science gather information mitochondrial-based treatments
Language: Английский
Citations
0
Gut Pathogens, Journal Year: 2024, Volume and Issue: 16(1)
Published: July 3, 2024
Nonalcoholic fatty liver disease (NAFLD) is increasingly recognized as a significant health issue. Emerging research has focused on the role of gut microbiota in NAFLD, emphasizing gut-liver axis. This study aimed to identify key trends and guide future investigations this evolving area.
Language: Английский
Citations
2
Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15
Published: July 17, 2024
Background Platycodin D (PD) has been reported to treat metabolic diseases, including non-alcoholic fatty liver disease. In addition, platycodin activate intestinal 5'AMP-activated protein kinase (AMPK) phosphorylation levels, thereby reducing lipid absorption. Therefore, the aim of this study is explore whether PD activation AMPK and reduced absorption can improve Methods Clean-grade male C57/BL mice were fed a high-fat diet (HFD) (containing 60% calories) for 16 weeks, oral (10 mg/kg/day) was administered at same time. The intestines collected, tested. expressions genes (CD36, NPC1L1, ApoB), serum total triglyceride (TG) cholesterol (TC) levels in livers, fecal free acid (FFA) expression phosphorylated proteins examined using Western blot analyses. distribution intestines, fat detected Oil Red O hematoxylin eosin (H&E) staining. A colon cancer cell line (Caco2) used confirm effect on cellular uptake vitro . inflammatory factors enzymes measured clarify impact circulation syndrome. Leptin-deficient (OB) then further improvement body weight blood lipids. Results had very significant therapeutic or preventive syndrome induced by diet. improved weight, insulin sensitivity, glucose tolerance also prevented disease, increased excretion. activating protein, which may have involved inhibition gene ApoB). combined these hepatic accumulation adipose tissue. It found that weights leptin-deficient mice. Conclusion strong under diet-induced obesity disease inhibiting
Language: Английский
Citations
2