European Journal of Translational Myology, Journal Year: 2023, Volume and Issue: 33(3)
Published: Sept. 20, 2023
This correspondence discusses a published article on the effects of physical activity Long COVID fatigue. Confounding factors are possible and should be acknowledged. When managing COVID-19 fatigue, you need to worry about other causes problem.
Language: Английский
Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 352, P. 296 - 305
Published: Feb. 13, 2024
Depression and fatigue are commonly observed sequelae following viral diseases such as COVID-19. Identifying symptom constellations that differentially classify post-COVID depression may be helpful to individualize treatment strategies. Here, we investigated whether self-reported associated with the same or different constellations. To address this question, used data from COVIDOM, a population-based cohort study conducted part of NAPKON-POP platform. Data was collected in three German regions (Kiel, Berlin, Würzburg). We analyzed >2000 individuals at least six months past PCR-confirmed COVID-19 disease, using elastic net regression cluster analysis. The model developed Kiel set, externally validated sets Berlin Würzburg. Our results revealed overlapping consisting difficulties daily activities, perceived health-related quality life, chronic exhaustion, unrestful sleep, impaired concentration. Confirming overlap constellations, follow-up analysis could categorize scoring high low on but not differentiate between both dimensions. presented cross-sectional, primarily questionnaire medical records rather than biometrically data. In summary, our suggest strong link thus highlighting need for integrative approaches.
Language: Английский
Citations
7
Microbiology Australia, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
'Long COVID' is a major dilemma, difficult to diagnose and even more challenging treat. Millions are still being affected globally ~10% of people experience Long COVID following acute infection. Many complain about fatigue, brain fog mental difficulties, ~200 symptoms described making diagnosis difficult. Both COVID-19 can cause organ damage – involving the heart, lungs, kidneys, brain; as well inflammation, studies suggest that severe dominated by endothelial immunological dysfunction, immunothrombosis. Diagnostic tests for largely in development finding effective therapies has been challenge; however, it likely antivirals have role preventing treating COVID. Real-world data support effectiveness vaccines reducing risk remains challenge needs considerable on-going research determine treatments. The global public health emergency may be over but fallout will with us some time.
Language: Английский
Citations
2
Published: July 4, 2024
This narrative review examines the crucial role of physical activity in managing long COVID, characterized by persistent symptoms such as fatigue, breathlessness, and cognitive impairments following SARS-CoV-2 infection. The methodology involved a comprehensive literature search across PubMed, EBSCO (EDS), Google Scholar, selecting peer-reviewed articles from December 2019 focusing on long-term COVID interventions. highlights that tailored exercise programs, adjusted to individual health status abilities, significantly alleviate enhance psychological well-being. Key findings emphasize importance personalized prescriptions due variability patient responses need for multidisciplinary approach developing monitoring Despite promising outcomes, identifies research gaps, including studies, randomized controlled trials, deeper mechanistic insights. It suggests standardized reporting, templates like CERT, integrating digital tools are essential optimizing Overall, advocates programs standard care improve outcomes quality life.
Language: Английский
Citations
1
Methods, Journal Year: 2024, Volume and Issue: 231, P. 186 - 194
Published: Oct. 9, 2024
Individuals with Post COVID-19 condition (PCC), or long COVID, experience symptoms such as fatigue, muscle weakness, and psychological distress, including anxiety, depression, sleep disorders that persist after recovery from COVID-19. These ongoing significantly compromise quality of life diminish functional capacity independence. Multimodal digital interventions targeting behavioural factors nutrition mindfulness have shown promise in improving health outcomes people chronic conditions may be beneficial for those PCC. The BLEND study (weB-based pLatform to improve nutrition, mindfulnEss, physical function, patients loNg COVID) is an 8-week pilot randomized controlled trial evaluating the feasibility a wellness platform compared usual care among individuals web-based employed this study, My Viva Plan (MVP)®, integrates holistic, multicomponent approach promote wellness. intervention group receives access 8 weeks encouragement frequent interactions dietary intake mindfulness. control general content focusing on improvements Assessments are conducted at baseline week 8. primary outcome use. Secondary exploratory include between-group comparison changes body composition, nutritional status, life, mindfulness, activity, performance weeks. Findings will inform development effective programs tailored PCC sustainable improved outcomes.
Language: Английский
Citations
1
Published: Jan. 11, 2024
Background: Depression and fatigue are commonly observed sequelae following viral diseases such as COVID-19. Identifying symptom constellations that differentially classify post-COVID depression may be helpful to individualize treatment strategies. Here, we investigated whether self-reported associated with the same or different constellations. Methods. To address this question, used data from COVIDOM, a population-based cohort study conducted part of NAPKON-POP platform. Data was collected in three German regions (Kiel, Berlin, Würzburg). We analyzed more than 2000 individuals at least six months past PCR-confirmed COVID-19 disease, using elastic net regression cluster analysis. The model developed Kiel set, externally validated sets Berlin Würzburg. Results. Our results revealed overlapping consisting difficulties daily activities, perceived health-related quality life, chronic exhaustion, unrestful sleep, impaired concentration. Confirming overlap constellations, follow-up analysis could categorize scoring high low on but not differentiate between both dimensions. Limitations. presented cross-sectional, primarily questionnaire medical records rather biometrically data.Conclusions. In summary, our suggest strong link thus highlighting need for integrative approaches.
Language: Английский
Citations
0
Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15
Published: June 20, 2024
Background Persistent post-infectious symptoms, predominantly fatigue, characterize Long COVID. This study investigated the efficacy of Myelophil (MYP), which contains metabolites extracted from Astragalus membranaceus and Salvia miltiorrhiza using 30% ethanol, in alleviating fatigue among subjects with Methods In this prospective observational study, we enrolled significant related to COVID, criteria scores 60 or higher on modified Korean Chalder Fatigue scale (mKCFQ11), five Visual Analog Scale (VAS) for brain fog. Utilizing a single-arm design, participants were orally administered MYP (2,000 mg daily) 4 weeks. Changes severity assessed mKCFQ11, Multidimensional Inventory (MFI-20), VAS addition, changes quality life short form 12 (SF-12) also along plasma cortisol levels. Results A total 50 (18 males, 32 females) enrolled; 49 included intention-to-treat analysis 66.9 ± 11.7 mKCFQ11 6.3 1.5 fog VAS. After weeks administration, there statistically improvements levels: was measured at 34.8 17.1 3.0 1.9. Additionally, MFI-20 decreased 64.8 9.8 49.3 10.8, dropped 7.4 1.0 3.4 1.7, SF-12 rose 53.3 14.9 78.6 14.3, levels elevated 138.8 50.1 176.9 62.0 /mL. No safety concerns emerged during trial. Conclusion Current findings underline MYP’s potential managing COVID-induced fatigue. However, comprehensive studies remain imperative. Clinical Trial Registration https://cris.nih.go.kr , identifier KCT0008948.
Language: Английский
Citations
0
Healthcare, Journal Year: 2024, Volume and Issue: 12(15), P. 1539 - 1539
Published: Aug. 3, 2024
This narrative review explores the essential role of physical activity in managing long COVID, which is characterized by persistent symptoms such as fatigue, breathlessness, and cognitive impairments following SARS-CoV-2 infection. In this context, “physical activity” includes various exercises, aerobic resistance training, well flexibility balance thereby encompassing subset known “exercise”. The methodology involved a comprehensive literature search across PubMed, EBSCO (EDS), Google Scholar, selecting peer-reviewed articles from December 2019 to June 2024 focusing on COVID interventions. highlights that tailored exercise programs, adjusted individual health status abilities, significantly alleviate enhance psychological well-being. Key findings emphasize importance personalized prescriptions due variability patient responses need for multidisciplinary approach developing monitoring Despite promising outcomes, identifies research gaps, including long-term studies, randomized controlled trials, deeper mechanistic insights. It suggests standardized reporting, templates like Consensus Exercise Reporting Template (CERT), integrating digital tools are optimizing Overall, advocates or programs standard care improve outcomes quality life.
Language: Английский
Citations
0
Der Nervenarzt, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 4, 2024
Citations
0
European Journal of Translational Myology, Journal Year: 2023, Volume and Issue: 33(3)
Published: Sept. 20, 2023
The authors of the Comments on: Effect physical activity on long COVID fatigue by Daungsupawong F. and Wiwanitkit V. (2023) have highlighted certain aspects future research that need to be considered before any conclusions can drawn regarding effect previous and/or fitness course long-COVID. We only agree with this need, although we hope effects SARS-CoV-2 infection will become less burdensome manage. As hypothesise in last part article Coscia et al. (2023), think it is crucial identify molecular mechanism underlying atrophic (if any) described disease states, which could originate from a local inflammatory storm induced Spike binding ACE-2 receptor muscle. When studies muscle patients available sufficient numbers, able try answer still open questions.
Language: Английский
Citations
1
European Journal of Translational Myology, Journal Year: 2023, Volume and Issue: 33(3)
Published: Sept. 20, 2023
This correspondence discusses a published article on the effects of physical activity Long COVID fatigue. Confounding factors are possible and should be acknowledged. When managing COVID-19 fatigue, you need to worry about other causes problem.
Language: Английский
Citations
1