Advances in Gut Microbiota-Targeted Therapeutics for Metabolic Syndrome
Yu Gao,
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Wujuan Li,
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Xiaoyu Huang
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et al.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(5), P. 851 - 851
Published: April 24, 2024
Previous
investigations
have
illuminated
the
significant
association
between
gut
microbiome
and
a
broad
spectrum
of
health
conditions,
including
obesity,
diabetes,
cardiovascular
diseases,
psychiatric
disorders.
Evidence
from
certain
studies
suggests
that
dysbiosis
microbiota
may
play
role
in
etiology
obesity
diabetes.
Moreover,
it
is
acknowledged
dietary
habits,
pharmacological
interventions,
psychological
stress,
other
exogenous
factors
can
substantially
influence
microbial
composition.
For
instance,
diet
rich
fiber
has
been
demonstrated
to
increase
population
beneficial
bacteria,
whereas
consumption
antibiotics
reduce
these
advantageous
communities.
In
light
established
correlation
various
pathologies,
strategically
altering
profile
represents
an
emerging
therapeutic
approach.
This
be
accomplished
through
administration
probiotics
or
prebiotics,
which
aim
refine
and,
consequently,
mitigate
manifestations
associated
diseases.
The
present
manuscript
evaluates
recent
literature
on
relationship
metabolic
syndrome
published
over
past
three
years
anticipates
future
directions
this
evolving
field.
Language: Английский
Association of Dietary Fiber and Measures of Physical Fitness with High-Sensitivity C-Reactive Protein
Ming-Zhen Su,
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Su‐Yeon Lee,
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Dayeon Shin
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et al.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(6), P. 888 - 888
Published: March 19, 2024
Dietary
fiber
intake
and
physical
fitness
are
independently
associated
with
high-sensitivity
C-reactive
protein
(hs-CRP)
levels.
Nevertheless,
the
association
between
dietary
intake,
measures
of
fitness,
hs-CRP
levels
has
not
yet
been
fully
evaluated.
We
investigated
influence
a
combination
including
hand
grip
strength,
resistance
training,
metabolic
equivalents
tasks,
on
Data
collected
from
Korea
National
Health
Nutrition
Examination
Survey
(KNHANES)
spanning
2015
to
2018
were
used
in
this
study.
A
total
16,934
participants
(7434
men
9500
women
aged
≥19
years)
included
After
adjusting
for
confounding
factors
(age,
education,
income,
marital
status,
smoking
drinking
habits,
energy
aerobic
activity),
we
employed
multivariable
logistic
model
examine
Among
women,
odds
high
lower
those
highest
superior
strength
compared
lowest
weaker
(odds
ratio
[OR]
=
0.40,
95%
confidence
interval
[CI]
0.24-0.68).
The
who
participated
exercise
at
least
three
times
per
week
had
reduced
did
engage
both
(OR
0.53,
CI
0.32-0.89;
OR
0.19-0.84,
respectively).
Our
findings
indicate
that
elevated
Language: Английский
Dietary calcium intake in relation to metabolic syndrome in adults: A systematic review and dose–response meta‐analysis of epidemiological studies with GRADE assessment
Obesity Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 8, 2024
Summary
Numerous
studies
have
examined
the
relationship
of
calcium
intake
and
metabolic
syndrome
(MetS)
in
adults
previous
decades;
but
results
were
inconsistent
across
different
societies.
This
systematic
review
dose–response
meta‐analysis
assessed
relation
between
consumption
MetS
adults.
We
did
a
search
all
articles
published
up
to
July
2023
Scopus,
PubMed/Medline,
ISI
Web
Science
electronic
databases,
Google
Scholar.
Observational
investigated
association
dietary
(Ca)
eligible
be
included.
For
computing
estimates,
random
effects
model
was
applied.
Combining
24
effect
size
from
17
investigations
(15
cross‐sectional
two
cohort
studies)
with
74,720
participants
18,200
cases
showed
that
highest
versus
lowest
level
Ca
related
23%
significant
decreased
odds
(OR
=
0.77;
95%
CI:
0.66,
0.89).
Linear
analysis
estimates
12
each
100
mg/day
increment
associated
3%
marginally
0.97;
95%CI:
0.93,
1.01).
In
nonlinear
67,896
participants,
found
(P
nonlinearity
<0.001);
such
500
maximum
decrease
MetS.
According
this
meta‐analysis,
likelihood
significantly
lower
higher
intake.
Further
large‐scale
prospective
are
needed
obtain
stronger
more
accurate
results.
Language: Английский