The Role of Polyphenols in Abiotic Stress Tolerance and Their Antioxidant Properties to Scavenge Reactive Oxygen Species and Free Radicals

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 74 - 74

Published: Jan. 10, 2025

Plants have evolved complex mechanisms to cope with diverse abiotic stresses, the phenylpropanoid pathway playing a central role in stress adaptation. This produces an array of secondary metabolites, particularly polyphenols, which serve multiple functions plant growth, development, regulating cellular processes, and responses. Recent advances understanding molecular underlying metabolism revealed regulatory networks involving MYB transcription factors as master regulators their interactions signaling pathways. review summarizes our current polyphenol-mediated adaptations plants, emphasizing regulation function key compounds. We discussed how various including heat chilling stress, drought, salinity, light UV radiation, nanoparticles chemical heavy metal toxicity, modulate trigger accumulation specific polyphenolic The antioxidant properties these phenolic acids, flavonoids, anthocyanins, lignin, roles reactive oxygen species scavenging, neutralizing free radicals, membrane stabilization, osmotic adjustment are discussed. Understanding metabolic responses is crucial for developing stress-resilient crops improving agricultural productivity under increasingly challenging environmental conditions. provides comprehensive insights into integrating adaptation mechanisms, highlighting potential targets enhancing crop tolerance through adjustment.

Language: Английский

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Comparative Metabolic Profiling and Biological Evaluation of Essential Oils from Conocarpus Species: Antidiabetic, Antioxidant, and Antimicrobial Potential

Plants, Journal Year: 2025, Volume and Issue: 14(3), P. 464 - 464

Published: Feb. 5, 2025

Essential oils (EOs) are a diverse source of bioactive compounds with remarkable therapeutic potential. Despite their significance, Conocarpus EOs have been largely underexplored. This study provides novel comparison the metabolic profiles and biological activities from C. lancifolius, erectus green, silver leaves cultivated in United Arab Emirates (UAE), offering unique insights into distinct properties potential applications. were extracted via hydro-distillation, analyzed using gas chromatography–mass spectrometry (GC-MS), subjected to chemometric analysis. Their antioxidant (2,2-diphenyl-1-picrylhydrazyl (DPPH) ferric reducing ability plasma (FRAP) assays), antidiabetic (α-amylase α-glucosidase inhibition), acetylcholinesterase (AChE) inhibition antimicrobial assessed. A total 92 metabolites identified, heptacosane nonacosane as key species discriminants. lancifolius EO showed strongest α-amylase (IC50 8.75 ± 0.54 µg/mL) 22.31 0.92 inhibitory activities, while demonstrated superior capacity 349.78 8.26 µg/mL, DPPH assay). exhibited best activity, particularly against Staphylococcus aureus (MIC 625 µg/mL). inhibited E. coli albicans In contrast, no activity Aspergillus niger. These findings highlight antioxidants for managing diabetes that may be utilized either nutraceuticals, dietary supplements or even pharmaceutical formulations. Moreover, owing significant added medical disinfectants several products. However, further, vivo validation exploration is still needed.

Language: Английский

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Dynamic Changes in Functional Components of Dendrobium officinale and Their Applications in Food Science: A Review

Plant Foods for Human Nutrition, Journal Year: 2025, Volume and Issue: 80(1)

Published: Feb. 10, 2025

Language: Английский

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Identification of α-Glucosidase Inhibitors and Assessment of Human Safety from 491 Native Plant Species of Jeju Island

Cosmetics, Journal Year: 2025, Volume and Issue: 12(2), P. 40 - 40

Published: Feb. 28, 2025

In contemporary society, obesity has become a critical public health issue driven by lifestyle modifications such as unhealthy dietary patterns, physical inactivity, and aging. Beyond its aesthetic implications, is significant etiological factor for metabolic disorders, including type 2 diabetes cardiovascular diseases. With increasing emphasis on weight management holistic health, the demand slimming cosmetics risen substantially. particular, formulation of natural-origin cosmetic ingredients that facilitate lipolysis improve dermal elasticity being actively investigated, presenting compelling balance safety efficacy. This study examined bioactivities 570 plant extracts sourced from Jeju Island to evaluate their potential raw materials. The α-glucosidase inhibitory activity was analyzed determine antidiabetic potential. Among tested extracts, 18 species, Rumex japonicus (IC50, 0.93 ± 0.21 μg/mL), Rhynchosia volubilis 1.2 0.16 Arachniodes standishii 4.88 0.89 exhibited substantially lower IC50 values compared positive control, acarbose 251.17 22.67 μg/mL). These findings highlight these innovative inhibitors, potentially serving alternatives conventional pharmacological agents. Additionally, topical application assessed via cytotoxicity assays using human keratinocyte (HaCaT) cells primary skin irritation tests. results indicated no in HaCaT evidence at concentrations deemed non-toxic cells. summary, exhibit promise multifunctional ingredients, combining properties through adipogenesis inhibition with skin-enhancing benefits.

Language: Английский

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Insight into endophytic microbiota-driven geographical and bioactive signatures toward a novel quality assessment model for Codonopsis Radix

Plant Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 109888 - 109888

Published: April 1, 2025

Language: Английский

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Predicting the Potential Distribution of Lagotis Medicinal Plants on the Qinghai‐Xizang Plateau, With a Maximum Entropy Model

Ecology and Evolution, Journal Year: 2025, Volume and Issue: 15(4)

Published: April 1, 2025

ABSTRACT Lagotis is a Tibetan medicine with high medicinal and research value in the Qinghai‐Xizang Plateau region. Predicting its potential suitable areas can provide important references for protection of . This study investigated collected 769 site data six species 28 environmental factor data, used maximum entropy model (MaxEnt) to simulate distribution under three climate scenarios (RCP2.6, RCP6.0, RCP8.5) 2050s 2070s. The results showed that: (1) AUC values training dataset were all > 0.94, indicating that predictions accurate. (2) Altitude (alt), isothermality (bio3), average annual precipitation (bio12) main factors affecting geographical (3) Under current conditions, increase greenhouse gas emission concentration, genus plants are primarily located eastern, central, southern parts Plateau. (4) Compared present period, integra , angustibracteata ramalana area will expand future. suitability macrosiphon shows an increasing trend. moderate brachystachya decreasing, while increasing. In contrast, brevituba decreased greatly. (5) found survival high‐altitude, low‐temperature areas. findings basis cultivation breeding Plateau, migration protection, construction nature reserve communities.

Language: Английский

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Predicting the potential habitats of two Lycium species and the quality suitability of Lycium Chinese Mill. Cortex under climate change

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Lycii Cortex is a frequently utilized traditional Chinese medicine with notable therapeutic properties. The impact of climate change on its distribution and quality significant concern. In this study, it investigated the geographic two sources plants for collected data samples from different origins via an online survey. HPLC was employed to ascertain concentrations kukoamine B A in samples. Subsequently, integrated ecological factor were forecast prospective expansion areas Lycium Chinese Mill. barbarum L. under future climatic conditions, migration trajectory suitable habitat centers mass, potential factors at varying times using Maxent ArcGIS. current scenario indicates that habitats barbarum are primarily distributed northern, northwestern, southwestern regions China, while Chinese predominantly central, southern, southeastern China. RCP4.5 2050s 2070s, total area deemed both species significantly reduced. mean center shifted towards higher latitudes, lower latitudes. It predicted future, would appear decrease. results study can provide reference determination cultivation China sustainable development Lycium resources.

Language: Английский

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Mining the Candidate Transcription Factors Modulating Tanshinones’ and Phenolic Acids’ Biosynthesis Under Low Nitrogen Stress in Salvia miltiorrhiza

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1774 - 1774

Published: Feb. 19, 2025

Mining valuable genes is helpful to breed high-quality Salvia miltiorrhiza exhibiting efficient nitrogen fertilizer utilization efficiency. In the present study, transcriptome sequencing was introduced select candidate transcription factors (TFs) involved in tanshinones' (TAs) and phenolic acids' (PHAs) biosynthesis as well low (LN) stress. totally, 97.71 Gb clean data obtained from fifteen samples 30,975 unigenes were assembled. Among of them, 27,843 successfully annotated. Overall, 8663 differential expression (DEGs) identified, among which 5034 up-regulated, 3629 down-regulated. By enrichment DEGs together with gene co-expression network construction, 10 TFs including HSFB2b, LBD12, ERF1A, ERF98, LBD25, HSF24, RAM1, HSFA4B, TCP8, WRKY24 finally retrieved, are predicted participate modulating TA PHA under LN Quantitative real-time polymerase chain reaction (qRT-PCR) detection further detect profile These findings offer a resource for in-depth study TAs 'and PHAs' stress S. miltiorrhiza.

Language: Английский

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Phytochemical Profile, Antioxidant and Antimicrobial Activity of Two Species of Oak: Quercus sartorii and Quercus rysophylla

Applied Biosciences, Journal Year: 2025, Volume and Issue: 4(1), P. 13 - 13

Published: March 4, 2025

The genus Quercus (Fagaceae) is one of the most widely distributed and species-diverse trees in Northern Hemisphere. present study addresses investigation phyto-chemical profile by ten assays, antioxidant activity scavenging DPPH radicals, total phenolic content, flavonoids, antimicrobial against three pathogenic bacteria with foliage two species red oak (Quercus sartorii rysophylla). Both showed a high content aqueous extract (22,342.10 ± 3076.5 mg GAE/kg plant 17,747.14 1139.9 plant, respectively). In flavonoid Q. higher amount ethanolic (24,587.42 996.3 QE/kg plant), while for rysophylla, it was methanolic (19,875.66 2754.01 plant). radical activity, highest percentage inhibition (81.14 1.7%), (82.60 2.7%). tests, halos were obtained strains Acinetobacter baumannii Staphylococcus aureus both species. All this gives guideline to comprehensively elucidate metabolites these further application dispute or diseases related imbalance reactive oxygen (ROS).

Language: Английский

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Antioxidant profiling and quality assessment of Lithocarpus polystachyus sweet tea using LC-ECD and LC-MS/MS

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 16, 2025

Abstract This study used liquid chromatography-electrochemical detection (LC-ECD) combined with chromatography-tandem mass spectrometry (LC-MS/MS) to screen and characterize the antioxidant components of sweet tea ( Lithocarpus polystachyus ), evaluate quality samples from different origins. First, total phenolic flavonoid content tea, as well in vitro activity, including ABTS DPPH radical scavenging capacities ferric reducing ability, were determined. Samples origins demonstrated potent correlation coefficients exceeding 0.8 between activities. Then, fingerprints generated by LC-ECD 22 common peaks identified LC-MS/MS, most them being phloretin derivatives. The clustering heat map revealed differences various regions, major compounds trilobatin, phlorizin, 3-hydroxyphlorizin, its isomer. Furthermore, grey relational analysis confirmed a strong association (protocatechuic acid, epicatechin, isoquercitrin, trilobatin) trilobatin showing highest contribution, reaching 0.9. Finally, 11 quantitatively screened using providing guidance for control.

Language: Английский

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