Phenolic Compound Characterization and Biological Activities of Mistletoe (Viscum album L.) Ethanol Macerates Used in Herbal Spirit Production DOI Creative Commons
Karla Hanousek Čiča, Damir Stanzer, Zoran Zorić

et al.

Beverages, Journal Year: 2024, Volume and Issue: 10(2), P. 41 - 41

Published: May 24, 2024

Biska, a traditional Istrian herbal spirit, is produced by macerating mistletoe leaves and twigs in water–ethanol base, usually grape marc spirit. The aim of this study was to determine the optimal maceration parameters (ethanol content, concentration plant material, duration) for production biska, which have not yet been subject scientific research. prepared macerates collected biska samples were subjected phenolic compound characterization, including total content (TPC), flavonoid (TFC), polyphenolic profile, ultra-high-performance liquid chromatography coupled with mass spectrometry (UPLC-ESI-MS2). In addition, analyzed their biological properties: antioxidant antiproliferative activity. results showed that both contain compounds such as acids, flavonoids, coumarins, contribute observed activities—significant activity effect. By applying parameters, yielded highest well volatile aromatic (40–80 g/L mistletoe, 40–55% v/v ethanol, 21 days’ time), process can be improved produce better properties.

Language: Английский

The Anti-Inflammatory Activity of Viscum album DOI Creative Commons
Marcello Nicoletti

Plants, Journal Year: 2023, Volume and Issue: 12(7), P. 1460 - 1460

Published: March 27, 2023

The therapeutic story of European mistletoe (

Language: Английский

Citations

38
The Interdependence Between Diet, Microbiome, And Human Body Health - A Systemic Review DOI Creative Commons
Florina Miere, Mariana Ganea,

Csaba Nagy

et al.

Pharmacophore, Journal Year: 2022, Volume and Issue: 13(2), P. 1 - 6

Published: Jan. 1, 2022

Recent studies from the literature show more and interdependence between diet intestinal microbiome health of human body microbiome. It has been shown so far that is itself an “organ” its metabolic activity influencing entire metabolism host. In this paper, main roles microbiome, composition, implications in maintaining organism

Language: Английский

Citations

20
Biotechnological Potential of Different Organs of Mistletoe (Viscum album L.) Collected from Various Host Tree Species in an Urban Area DOI Creative Commons
Liubov Skrypnik, Pavel Feduraev,

Anton Golovin

et al.

Plants, Journal Year: 2022, Volume and Issue: 11(20), P. 2686 - 2686

Published: Oct. 12, 2022

From an economic and ecological standpoint, it is crucial to investigate the biologically active compounds of mistletoe plants, which are currently discarded by pruning urban mistletoe-infested trees. In present study, content phenolic compounds, triterpenic organic acids, as well antioxidant activity extracts various organs (leaves, stems, fruits) collected from most infested tree species were investigated. The samples Betula pendula, Acer platanoides, Crataegus monogyna, Sorbus aucuparia showed highest acids flavonoids activity, measured 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), ferric reducing/antioxidant power (FRAP) assays. leaves stems Tilia cordata characterized a high (oleanolic, ursolic, betulinic). fruits plants Populus nigra Salix alba contained concentration particularly succinic citric acids. Compared stem leaf extracts, fruit was 1.5-3 times higher. obtained results indicate that valuable raw material can be used source for producing with properties.

Language: Английский

Citations

17
Phytochemical Profile and Antioxidant Capacity of Viscum album L. Subsp. album and Effects on Its Host Trees DOI Creative Commons

Eva Kleszken,

C. Purcărea, Annamária Pallag

et al.

Plants, Journal Year: 2022, Volume and Issue: 11(22), P. 3021 - 3021

Published: Nov. 9, 2022

Viscum album L. subsp. is a hemiparasitic plant that recognized as medicinal due to its beneficial effects, including anti-tumor activity, antioxidant, anti-inflammatory, anti-hepatotoxic, hypoglycemic, and antimicrobial properties well for lowering blood pressure. On the other hand, mistletoe biotic stressor both deciduous trees conifers. Our main aim was evidence influence of on content chlorophylls, proline, total phenols, flavonoids, antioxidant capacity leaves from tree host (Malus domestica, Prunus Populus alba) grow northwest Romania. In addition, HPLC-DAD-MS-ESI+ used analyze phenolic acid flavonoid profiles V. according their parasitized hosts. A significant decrease in chlorophyll level approximately 32% detected poplars infested with mistletoe, followed by apples plums pigment reductions 29.25% 9.65%, respectively. The phenols flavonoids higher compared non-parasitized ones. case poplar, which presented highest incidence infestation (70.37%), two times non-infested leaves. Based HPLC chromatographic analysis, growing apple (VAM) had acids (7.833 mg/g dw), poplar (VAO) plum (VAP) (7.033 dw and, respectively, 5.559 dw). Among flavonols, predominant component Rhamnazin glucosides amount 1.025 ± 0.08 VAO, VAP VAM (0.514 0.04 0.478 dw, respectively). Although our results show negatively influences trees, it still valuable must be exploited bring benefits human health.

Language: Английский

Citations

17
Romanian Viscum album L.—Untargeted Low-Molecular Metabolomic Approach to Engineered Viscum–AuNPs Carrier Assembly DOI Creative Commons
Adina‐Elena Segneanu, C.N. Marin, Dumitru-Daniel Herea

et al.

Plants, Journal Year: 2022, Volume and Issue: 11(14), P. 1820 - 1820

Published: July 11, 2022

Viscum is one of the most famous and appreciated medicinal plants in Europe beyond. The symbiotic relationship with host tree various endogenous ecological aspects are main factors on which viscum metabolites' profiles depend. In addition, European traditional medicine mentions that only two periods year (summer solstice winter solstice) therapeutic potential plant at its maximum. Many studies have investigated phytotherapeutic properties grown different species trees. However, Romanian relatively few refer mainly to antioxidant antiproliferative activity mistletoe Acer campestre, Fraxinus excelsior, Populus nigra, Malus domestica, or Robinia pseudoacacia. This study reports first complete low-molecular-weight metabolite profile wild-grown viscum. A total 140 metabolites were identified under mass spectra (MS) positive mode from 15 secondary categories: flavonoids, amino acids peptides, terpenoids, phenolic acids, fatty organic nucleosides, alcohols esters, amines, coumarins, alkaloids, lignans, steroids, aldehydes, miscellaneous. biological each class discussed. development a simple selective phyto-engineered AuNPs carrier assembly reported an evaluation nanocarrier system's morpho-structure performed, capitalize beneficial AuNPs.

Language: Английский

Citations

16
Decolonizing Pharmaceutical Services and Professionalism: Toward Equity and Inclusivity in Integrative Healthcare in Ethiopia DOI Creative Commons
Tsegaye Melaku,

Desta Assefa,

Bodena Bayisa

et al.

Archives of Pharmacy Practice, Journal Year: 2025, Volume and Issue: 16(1), P. 19 - 26

Published: Jan. 1, 2025

Language: Английский

Citations

0
Medicinal Plants of the Flora of Kazakhstan Used in the Treatment of Skin Diseases DOI Creative Commons
Gulzat Berganayeva,

Bates Kudaibergenova,

Yuliya Litvinenko

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(10), P. 4192 - 4192

Published: May 19, 2023

The skin shows the physiological condition of body’s organs and systems that prevent infections physical damage. Throughout ages, in folk medicine, phytotherapy was considered a primary form treatment all countries, including Kazakhstan, due to abundance availability plant-based remedies. This paper discusses several medicinal plants are traditionally used diseases Republic Kazakhstan. chemical composition these analyzed, with particular focus on biologically active basic compounds responsible for their therapeutic efficiency treating ailments.

Language: Английский

Citations

8
Pharmacological Properties and Safe Use of 12 Medicinal Plant Species and Their Bioactive Compounds Affecting the Immune System DOI Creative Commons
Małgorzata Geszke-Moritz, Gerard Nowak, Michał Moritz

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(11), P. 6477 - 6477

Published: May 25, 2023

This paper presents raw plant materials and their characteristic compounds which may affect the immune system. Plant-derived agents in specific doses body’s non-specific, antigen-independent defense They have immunostimulatory effects on entire regulatory can enhance response through various factors such as macrophages, leukocytes, granulocytes, well mediators released by cellular was inspired threats caused COVID-19 pandemic. The proper functioning of system is important limiting viral infection restoring normal body. also emphasizes importance skillful use immunostimulants potential patients, but those who prescribe drugs. It not only to choose right drug above all correct dose duration treatment.

Language: Английский

Citations

7
Quality of Life in Breast Cancer Patients Treated With Mistletoe Extracts: A Systematic Review and Meta-Analysis DOI Creative Commons
Martin Loef, D. Paepke, Harald Walach

et al.

Integrative Cancer Therapies, Journal Year: 2023, Volume and Issue: 22

Published: Jan. 1, 2023

Background: Breast cancer is the most common type in women and quality of life an essential part patients’ well-being. Although treatment with mistletoe extracts covered by multiple guidelines reviews, it uncertain whether can improve breast patients. We therefore performed a systematic review meta-analysis on this topic. Methods: This included randomized clinical trials (RCTs) non-randomized studies intervention (NRSIs) comparing patients treated as add-on therapy to control groups conventionally. searched previous reviews databases until January 2023. conducted assessed risk bias according Cochrane Handbook via RoB 2 ROBINS-I certainty evidence GRADE, respectively. Results: Nine RCTs 7 NRSIs 833 2831 participants, respectively, were included. The pre-post changes for resulted pooled standardized mean difference SMD = 0.61 (95% CI 0.47-0.75; P < .0001) retrospective 0.46 0.10-0.82; .01). was low high serious all NRSIs. moderate very Discussion: Our results indicate clinically relevant, medium-sized effect which may be based immunomodulating effects during chemotherapy. limitations include mainly caused difficulty blinding. Further real-world need confirm result, especially setting neoadjuvant chemotherapy survivors.

Language: Английский

Citations

7
Determination of Antioxidant Activities of Viscum album L.: First Report on Interaction of Phenolics with Survivin Protein using in silico Analysis DOI
Safiye Elif Korcan, Nevin Çankaya, Serap Yalçın Azarkan

et al.

ChemistrySelect, Journal Year: 2023, Volume and Issue: 8(12)

Published: March 21, 2023

Abstract Mistletoe , Viscum album L., ( VA ) known as “Ökse Otu” in Turkey, is a hemiparasitic shrub that grows especially on the trunks and crowns of broadleaf trees. This study aimed to determination ’s antioxidant compounds evaluate their vitro activities growing twelve different host trees silico approach against survivin protein. At same time, active ingredients determined HPLC analysis, were performed with molecular docking dynamics analysis protein, an apoptosis inhibitor protein cancer. Antioxidant methanolic extracts organs determined. Phytochemical properties samples taken from hosts varied well. Total phenolic content was at highest rate fruits, followed by leaves branches, respectively. flavonoid amounts leaves, branches activity values evaluated DPPH (using radical), ABTS radical cation) FRP tests. The plant rate, During Quercetin, Rosmarinic acid Catechin found bind effectively. These substances can have potential become pharmaceutical working proteins future.

Language: Английский

Citations

6