Comparison of the 1% and 2% Pilocarpine Mouthwash in Xerostomic Patients, a Randomized Clinical Trial DOI Creative Commons

Babak Motamed,

Arezoo Alaee, Arash Azizi

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: May 31, 2022

Abstract Aims & Background: Pilocarpine is an accepted treatment for xerostomia, but limited research has been conducted on the oral topical form. This study aimed to compare effect of 1% and 2% pilocarpine mouthwash in xerostomic patients. Methods: In this double-blind clinical trial study, 48 patients with xerostomia referred were randomly divided into three groups measure placebo mouthwashes saliva levels. The amount 1 st 14 th days was measured at 0, 45, 60 75 minutes, while used their times a day days. On days, filled out information forms drug side effects before after intervention. Results: day, mean salivary flow 60, minutes significantly higher than group (p<0.05). time 45 (p=0.007). (p<0.001) (p=0.028) group. Also, these two times, No observed any Conclusions: showed that 5 ml weeks increased patients, respectively, compared without effects.

Language: Английский

Comparison of the 1 and 2% pilocarpine mouthwash in a xerostomic population: a randomized clinical trial DOI Creative Commons

Babak Motamed,

Arezoo Alaee, Arash Azizi

et al.

BMC Oral Health, Journal Year: 2022, Volume and Issue: 22(1)

Published: Dec. 1, 2022

Abstract Aims & background Pilocarpine is an accepted treatment for xerostomia, but limited research has been conducted on the oral, topical form. The present study aimed to compare effects of 1 and 2% pilocarpine mouthwash xerostomic participants. Methods In this double-blind clinical trial study, 48 subjects with xerostomia were randomly divided into three groups measure placebo mouthwashes saliva levels. amount in 1st 14th days was measured at 0, 45, 60, 75 mins, while participants used their times a day 14 days. On days, they filled out information forms medicine’s side before after intervention. Results day, mean salivary flow mins 2 1% significantly higher than group ( p < 0.05). time 45 = 0.007). Furthermore, 60 0.001) 0.028) group. Moreover, 0.05) during these two times. No observed any subjects. Conclusions showed that 5 ml weeks increased compared without effects.

Language: Английский

Citations

4
Comparison of the 1% and 2% Pilocarpine Mouthwash in Xerostomic Patients, a Randomized Clinical Trial DOI Creative Commons

Babak Motamed,

Arezoo Alaee, Arash Azizi

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: May 31, 2022

Abstract Aims & Background: Pilocarpine is an accepted treatment for xerostomia, but limited research has been conducted on the oral topical form. This study aimed to compare effect of 1% and 2% pilocarpine mouthwash in xerostomic patients. Methods: In this double-blind clinical trial study, 48 patients with xerostomia referred were randomly divided into three groups measure placebo mouthwashes saliva levels. The amount 1 st 14 th days was measured at 0, 45, 60 75 minutes, while used their times a day days. On days, filled out information forms drug side effects before after intervention. Results: day, mean salivary flow 60, minutes significantly higher than group (p<0.05). time 45 (p=0.007). (p<0.001) (p=0.028) group. Also, these two times, No observed any Conclusions: showed that 5 ml weeks increased patients, respectively, compared without effects.

Language: Английский

Citations

0