Early versus delayed necrosectomy in pancreatic necrosis: A population-based cohort study on readmission, healthcare utilization, and in-hospital mortality
World Journal of Methodology,
Journal Year:
2024,
Volume and Issue:
14(3)
Published: June 25, 2024
Acute
necrotizing
pancreatitis
is
a
severe
and
life-threatening
condition.
It
poses
considerable
challenge
for
clinicians
due
to
its
complex
nature
the
high
risk
of
complications.
Several
minimally
invasive
open
necrosectomy
procedures
have
been
developed.
Despite
advancements
in
treatment
modalities,
optimal
timing
perform
lacks
consensus.
Language: Английский
COVID-19, Possible Hepatic Pathways and Alcohol Abuse—What Do We Know up to 2023?
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(4), P. 2212 - 2212
Published: Feb. 12, 2024
The
pandemic
period
due
to
coronavirus
disease
2019
(COVID-19)
revolutionized
all
possible
areas
of
global
health.
Significant
consequences
were
also
related
diverse
extrapulmonary
manifestations
this
pathology.
liver
was
found
be
a
relatively
common
organ,
beyond
the
respiratory
tract,
affected
by
severe
acute
syndrome
coronavirus-2
(SARS-CoV-2).
Multiple
studies
revealed
essential
role
chronic
(CLD)
in
general
outcome
infection.
Present
concerns
field
are
direct
hepatic
caused
COVID-19
and
pre-existing
disorders
as
risk
factors
for
course
Which
mechanism
has
key
phenomenon—previously
existing
disorder
or
failure
SARS-CoV-2—is
still
not
fully
clarified.
Alcoholic
(ALD)
constitutes
another
elucidated
context
Should
toxic
effects
ethanol
already
developed
cirrhosis
its
perceived
causative
triggering
factor
impairment
patients?
In
face
these
discrepancies,
we
decided
summarize
whole
picture
infection,
paying
special
attention
ALD
focusing
on
pathological
pathways
COVID-19,
toxicity
cirrhosis.
Language: Английский
Impact of COVID-19 on liver transplant recipients: A nationwide cohort study evaluating hospitalization, transplant rejection, and inpatient mortality
World Journal of Transplantation,
Journal Year:
2024,
Volume and Issue:
14(2)
Published: June 13, 2024
BACKGROUND
The
coronavirus
disease
2019
(COVID-19)
pandemic
has
posed
a
major
public
health
concern
worldwide.
Patients
with
comorbid
conditions
are
at
risk
of
adverse
outcomes
following
COVID-19.
Solid
organ
transplant
recipients
concurrent
immunosuppression
and
comorbidities
more
susceptible
to
severe
COVID-19
infection.
It
could
lead
higher
rates
inpatient
complications
mortality
in
this
patient
population.
However,
studies
on
liver
(LT)
have
yielded
inconsistent
findings.
AIM
To
evaluate
the
impact
hospital-related
among
LT
United
States.
METHODS
We
conducted
retrospective
cohort
study
using
2019–2020
National
Inpatient
Sample
database.
primary
hospitalizations
secondary
diagnosis
were
identified
International
Classification
Diseases,
Tenth
Revision
coding
system.
included
trends
before
during
pandemic.
Secondary
comparative
rejection
recipients.
RESULTS
A
total
15720
hospitalized
included.
Approximately
0.8%
patients
had
In
both
cohorts,
median
admission
age
was
57
years.
linear
for
did
not
differ
significantly
(P
=
0.84).
frequency
in-hospital
increased
from
1.7%
4.4%
between
January
December
2020.
Compared
pre-pandemic
period,
association
noted
pandemic,
an
odds
ratio
(OR)
1.69
[95%
confidence
interval
(CI):
1.55-1.84),
P
<
0.001].
rejections
0.2%
3.6%
than
[OR:
1.53
(95%CI:
1.26-1.85),
CONCLUSION
hospitalization
comparable
Language: Английский