International Journal For Multidisciplinary Research,
Journal Year:
2024,
Volume and Issue:
6(4)
Published: July 27, 2024
Schiff
bases
exhibit
a
broad
spectrum
of
uses
in
the
industrial,
pharmacological,
and
biological
fields.
With
particular
focus
on
base
heterocyclic
moiety
conjugates,
this
review
paper
provides
an
extensive
overview
synthesis,
reactions,
applications,
activities
bases.
It
explores
different
approaches
to
synthesizing
base;
including
water-based
media,
conventional
methods,
metal-catalyzed
processes,
acidic
phase
transfer
catalysis,
ultrasonic
microwave
conditions,
grinding
chemistry
techniques.
Furthermore,
industrial
applications
bases,
particularly
as
corrosion
inhibitors,
are
highlighted.
The
also
delves
into
such
their
antimicrobial,
anticancer,
anti-inflammatory,
analgesic,
anthelmintic,
antioxidant
properties,
showcasing
potential
medicinal
applications.
aims
provide
comprehensive
understanding
versatile
roles
play
significant
contributions
advancing
various
scientific
practical
domains,
emphasizing
wide
ranging
benefits
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 4, 2024
Schiff
bases,
a
versatile
class
of
organic
compounds
with
(>C〓N∙)
functional
group,
have
gained
significant
attention
in
contemporary
chemistry
due
to
their
remarkable
synthesis
methods,
diverse
properties,
and
wide-ranging
applications.
This
book
chapter
focused
on
emphasizing
versatility
chemistry.
It
covers
structural
aspects,
applications
across
multiple
domains.
The
historical
development
bases
is
traced,
pivotal
role
modern
as
key
intermediates
various
processes.
delves
into
including
traditional,
sustainable,
green
approaches,
discusses
spectroscopic
characterization,
thermodynamic
kinetics.
are
categorized
types,
highlighting
diversity.
Applications
explored
catalysis,
asymmetric
synthesis,
coordination
chemistry,
medicinal
materials
science,
environmental
contexts.
concludes
recent
advances,
emerging
trends,
future
directions,
positioning
it
valuable
resource
for
researchers,
students,
practitioners
interested
bases.
proposed
aims
explore
the
latest
developments
providing
an
in-depth
review
scientific
fields.
Future Medicinal Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 11
Published: March 21, 2025
Aims
This
study
aimed
to
synthesize
and
characterize
a
Schiff
base
ligand,
(Z)-2-(2-oxoindolin-3-ylidene)hydrazinecarbothioamide
(1),
its
copper(II)
(2)
zinc(II)
(3)
complexes,
as
well
evaluate
their
binding
interactions
with
the
epidermal
growth
factor
receptor
(EGFR)
anticancer
activity
against
human
lung
cancer
A549
cell
line.
