European Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
26(22)
Published: May 3, 2023
Abstract
Five‐membered
difluoroboryl
chelate
complexes
are
competent
substrates
for
radical
reactions
with
various
precursors
including
potassium
trifluoroborates,
bis(catecholato)siliconates,
4‐alkyl‐substituted
Hantzsch
esters,
dihydroquinazolinones,
esters
of
N
‐hydroxyphthalimide,
Katritzky
salts,
alkyl
iodides
and
thiols.
Using
these
reagents,
primary,
secondary,
tertiary
radicals
can
be
generated
under
oxidative
or
reductive
conditions
add
at
the
C=N
bond
chelates
leading
to
hydrazide
products.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(29)
Published: March 24, 2023
Abstract
The
photoactivation
of
electron
donor‐acceptor
complexes
has
emerged
as
a
sustainable,
selective
and
versatile
strategy
for
the
generation
radical
species.
Electron
(EDA)
complexation,
however,
imposes
electronic
constraints
on
donor
acceptor
components
this
can
limit
range
radicals
that
be
generated
using
approach.
New
EDA
complexation
strategies
exploiting
sulfonium
salts
allow
to
from
native
functionality.
For
example,
aryl
salts,
formed
by
activation
arenes,
serve
in
due
their
electron‐deficient
nature.
This
“sulfonium
tag”
approach
relaxes
parent
substrate
dramatically
expands
complexation.
In
review,
these
new
applications
will
introduced
areas
chemical
space
rendered
accessible
through
innovation
highlighted.
Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(20), P. 7971 - 7977
Published: Jan. 1, 2023
Alkyl
diacyl
peroxides
were
demonstrated
to
be
efficient
alkylating
reagents
for
the
visible-light-induced
4CzIPN-catalyzed
direct
C–H
alkylation
of
N
-heteroaromatics.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(4), P. 2288 - 2295
Published: Feb. 4, 2023
A
simple
and
practical
electron
donor-acceptor
(EDA)
strategy
to
synthesize
various
3-alkylated
coumarins
from
easily
available
naturally
abundant
carboxylic
acids
under
photocatalyst-,
oxidant-,
additive-free
mild
conditions
is
reported.
Using
Na2S
as
the
catalytic
donor,
a
series
of
primary,
secondary,
tertiary
carbon
radicals
can
be
efficiently
generated,
EDA
complex
regenerated
without
an
alkaline
additive.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 14, 2024
Photosynthesis,
converting
sustainable
solar
energy
into
chemical
energy,
has
emerged
as
a
promising
craft
to
achieve
diverse
organic
transformations
due
its
mild
reaction
conditions,
sustainability,
and
high
efficiency.
The
synthesis
of
sulfonated
compounds
drawn
significant
attention
in
the
pharmaceuticals,
agrochemicals,
materials
industries
unique
structure
electronic
properties
sulfonyl
groups.
Over
past
decades,
many
photocatalytic
sulfonylation
reactions
have
been
developed.
In
this
review,
recent
advances
photocatalyzed
reviewed
since
2020,
with
primary
focus
on
discussing
design
mechanism.
Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
12(2)
Published: Jan. 11, 2023
Abstract
We
developed
a
novel
and
efficient
method
for
the
synthesis
of
various
3‐alkylated
quinoxalin‐2(1
H
)‐ones
(32
examples,
70%–96%
yields)
through
electron
donor‐acceptor
complex
enabled
alkylation
with
N
‐
hydroxyphthalimide
esters
as
alkyl
source
Na
2
S
catalytic
donor
under
external
photocatalyst‐,
oxidant‐
additive‐free
conditions.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(4), P. 2777 - 2781
Published: Feb. 5, 2024
2,1,3-Benzothiadiazole
is
widely
used
as
a
privileged
scaffold
in
pharmaceuticals
and
organic
functional
materials.
Nonetheless,
many
current
methods
for
the
functionalization
of
2,1,3-benzothiadiazole
rely
on
preactivation,
transition
metal
catalysts/promoters,
or
an
elevated
reaction
temperature.
Herein
we
disclose
transition-metal-free
visible-light-induced
photocatalytic
method
direct
C–H
alkylation
using
readily
accessible
carboxylic
acid
derivatives,
i.e.,
N-hydroxyphthalimide
esters
(NHPEs),
alkylating
reagents
under
room
This
mild
scalable
highlighted
by
late-stage
installation
benzothiadiazole
drugs
natural
products.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(15), P. 3174 - 3178
Published: April 8, 2024
A
concept
for
the
dual
use
of
acridine
and
tetrabutylammonium
decatungstate
photocatalysts
in
reactions
carboxylic
acids
is
proposed.
Imines
generated
situ
from
aldehydes
p-methoxyaniline,
as
well
other
azomethines,
were
used
radical
acceptors.
The
role
believed
to
facilitate
turnover
photocatalyst
by
means
hydrogen
atom
transfer.
