Periodontal Wound Healing and Tissue Regeneration: A Narrative Review

Pharmaceuticals, Journal Year: 2021, Volume and Issue: 14(5), P. 456 - 456

Published: May 12, 2021

Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate tissues. The periodontium complex structure composed of specialized tissues that support the teeth, most surgeries are invasive procedures, including resection gingiva or alveolar bone. wound healing process slightly different from cutaneous similar fetal healing, being almost scar-free. aim this review article provide an overview discuss surgical pharmaceutical approaches achieve stable improve treatment outcomes. In addition, detrimental limiting factors induce compromised prognosis discussed, along with perspective future direction for successful tissue regeneration.

Language: Английский

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Overview of Ultrasound in Dentistry for Advancing Research Methodology and Patient Care Quality with Emphasis on Periodontal/Peri-implant Applications

Zeitschrift für Medizinische Physik, Journal Year: 2023, Volume and Issue: 33(3), P. 336 - 386

Published: March 13, 2023

Ultrasound is a non-invasive, cross-sectional imaging technique emerging in dentistry. It an adjunct tool for diagnosing pathologies the oral cavity that overcomes some limitations of current methodologies, including direct clinical examination, 2D radiographs, and cone beam computerized tomography. Increasing demand soft tissue has led to continuous improvements on transducer miniaturization spatial resolution. The aims this study are (1) create comprehensive overview literature ultrasonic relating dentistry, (2) provide view onto investigations with immediate, intermediate, long-term impact periodontology implantology. A rapid review was performed using two broad searches conducted PubMed database, yielding 576 757 citations, respectively. rating established within citation software (EndNote) 5-star classification. search citations allowed high sensitivity whereas subsequent added specificity. critical applications ultrasound dentistry provided focus role as developing dental diagnostic reviewed. Specific uses such hard imaging, longitudinal monitoring, well anatomic physiological evaluation were discussed. Future efforts should be directed towards transition ultrasonography from research tool. Moreover, dedicated effort needed introduce education community ultimately improve quality patient care.

Language: Английский

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Calcium phosphate bone cements as local drug delivery systems for bone cancer treatment

Biomaterials Advances, Journal Year: 2023, Volume and Issue: 148, P. 213367 - 213367

Published: March 3, 2023

Bone cancer is usually a metastatic disease, affecting people of all ages. Its effective therapy requires targeted drug administration locally at the site so that surrounding healthy organs and tissues stay unharmed. Upon thorough literature search, tremendous number published articles are reporting on development calcium phosphate cements (CPCs) for treatment variety diseases, such as osteoporosis, osteoarthritis, osteomyelitis, other musculoskeletal disorders. However, just limited research employs CPCs specifically bone treatment. In this review article, we study factors influencing local release from particularly focus therapy. Finally, locate deficiencies in regarding specific topic propose which perspectives should be considered discussed future articles.

Language: Английский

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Early Wound Healing Score: a system to evaluate the early healing of periodontal soft tissue wounds

Journal of Periodontal & Implant Science, Journal Year: 2018, Volume and Issue: 48(5), P. 274 - 274

Published: Jan. 1, 2018

Purpose: Numerous indices have been proposed to analyse wound healing in oral soft tissues, but each has specific shortcomings.A new method of analysis, the Early Wound Healing Score (EHS), was evaluated present study.The aim assess more accurately early by primary intention surgical incisions periodontal tissues.Methods: Twenty-one patients were treated with different procedures comprising 1 or 2 vertical releasing as part a access flap.Twenty-four hours after surgery, at assessed using EHS.This score clinical signs re-epithelialization (CSR), haemostasis (CSH), and inflammation (CSI).Since complete epithelialization main outcome, CSR weighted be 60% total final score.Accordingly, 0, 3, 6 points possible for assessment CSR, whereas scores 1, CSH CSI.Higher values indicated better healing.Accordingly, ideal 10.Results: Thirty 21 patients.At 24 incision, 16 (53.33%) received maximum while cases (20%) an EHS 10.None 0 points. Conclusion:The system may useful tool assessing tissue surgery.

Language: Английский

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The biological width around implant

Journal of Prosthodontic Research, Journal Year: 2020, Volume and Issue: 65(1), P. 11 - 18

Published: Sept. 8, 2020

Purpose: The concept of biological width has been proposed and widely used in oral implantation. This review aimed to summarize the around implant detail. Study selection: An electronic search literature prior March 2019 was performed identify all articles related periimplant soft tissue. conducted MEDLINE (National Library Medicine) database accessed through PubMed with no date restriction. following main keywords were used: "implant", "biological width", "soft tissue", "junctional epithelium", "peri-implant "connective "gingiva", "mucosa" (connecting multiple AND, OR). Results: identified researches focused on several aspects implantation, namely concept, formation, remodeling, dimension, structure function. Conclusions: Based reviewed literature, structure, functional significances are explored this narrative review. formation is a complex process after weeks healing. 3-4mm distance from top peri-implant mucosa first bone-to-implant contact or stabilized adjacent bone, consisting sulcular epithelium, junctional epithelium fibrous connective tissue between bone. forms barrier against bacteria, influences remodeling hard implications for clinical dental

Language: Английский

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Jellyfish‐Inspired Artificial Spider Silk for Luminous Surgical Sutures

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 30, 2024

Abstract The development of functional surgical sutures with excellent mechanical properties, good fluorescence, and high cytocompatibility is highly required in the field medical surgeries. Achieving fibers that simultaneously exhibit robustness, spinnability, durable fluorescence emission has remained challenging up to now. Taking inspiration from spinning process spider silk luminescence mechanism jellyfish, this work reports a luminous artificial prepared aim balancing fiber spinnability robustness. This realized by employing hydrated segments aggregation‐induced for enhancing polyhydroxyl increasing Twist insertion during improves strength, toughness, emission. Furthermore, coating an additional polymer layer results “sheath–core” architecture improved properties capacity withstand water. provides new design strategy performing luminescent robust sutures.

Language: Английский

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Comparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trial

Clinical Oral Investigations, Journal Year: 2020, Volume and Issue: 24(12), P. 4549 - 4561

Published: May 18, 2020

Language: Английский

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Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

International Journal of Implant Dentistry, Journal Year: 2020, Volume and Issue: 6(1)

Published: Nov. 26, 2020

Abstract It is not uncommon to encounter post-surgical complications after horizontal guided bone regeneration (GBR). The primary aim of this review was evaluate the incidence and types that occur GBR propose management strategies deal with these clinical situations. A secondary conduct a histomorphometric wound healing process at sites experienced GBR. keyword search MEDLINE, EMBASE, Cochrane Central Register Controlled Trials for studies published in English from January 2015 2020 conducted 23 were selected. second addressing conducted, five included. Site-level analysis showed weighted mean proportion minor dehiscence infections occurring augmented site 9.9% [95% CI 6.4, 13.9, P < 0.01] 1.5% 0.4, 3.1, = 0.21) respectively. Patient-level major 16.1% 11.9, 20.8, 1.6% 0.0, 4.7, respectively, while neurosensory alterations donor 7.0% 1.3, 15.5, 0.01]. Subgroup also revealed use block grafts increased complications, whereas staged procedure both complications. Although exposure barrier membrane often associated less graft resorption, type used (resorbable or non-resorbable) had no statistically significant influence on any complication. Histologically, layer fibrous connective tissue instead commonly observed interface between native recipient regenerated cases procedure. Minor highest Methods ranging daily application antiseptics, systemic antimicrobials, regular reviews, total removal non-integrated biomaterials are prescribed manage attempt minimise loss surgical site.

Language: Английский

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The effects of injectable platelet-rich fibrin application on wound healing following gingivectomy and gingivoplasty operations: single-blind, randomized controlled, prospective clinical study

Clinical Oral Investigations, Journal Year: 2024, Volume and Issue: 28(1)

Published: Jan. 10, 2024

The aim of this study was to evaluate the effects wound healing using injectable platelet-rich fibrin (IPRF) after gingivectomy and gingivoplasty.

Language: Английский

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Assessment of healing following low-level laser irradiation after gingivectomy operations using a novel soft tissue healing index: A randomized, double-blind, split-mouth clinical pilot study

Journal of Indian Society of Periodontology, Journal Year: 2018, Volume and Issue: 23(1), P. 53 - 53

Published: Dec. 21, 2018

Lasers have become a part of modern dentistry since the past three decades. A wide-ranging assortment lasers is being used in periodontology for both soft and hard tissue surgical procedures. Regardless frequent practice using these well-known lasers, there another lesser familiar class called low-level lasers. The main doctrine behind laser therapy (LLLT) centered on biostimulation, or biomodulation effect, which relies dexterity low-intensity energy when irradiated at specific wavelength, able to modify cellular activities (increase cell metabolism fibroblast keratinocyte proliferation).The aim present study was investigate adjunctive use LLLT gingival healing after gingivectomy procedures.Ten systemically healthy patients requiring gingivoplasty procedures bilaterally either maxillary mandibular teeth were included study. After intervention, diode (810 nm) randomly activated one side operated area while other did not receive any treatment served as control. index given by Landry et al. evaluate immediately postsurgery 3rd day, 1 week, 2 weeks postoperatively. follow-up period, results analyzed appropriate statistical tests.There no statistically significant difference observed surface epithelialization between groups 7th-postoperative days, but highly differences 14th day.Within confines this pilot study, outcomes indicated that wound may be improved operations.

Language: Английский

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