Seminars in Roentgenology, Journal Year: 2024, Volume and Issue: 60(1), P. 19 - 30
Published: Dec. 19, 2024
Language: Английский
Advanced Materials, Journal Year: 2024, Volume and Issue: 36(27)
Published: March 29, 2024
Cancer treatment requires precise tumor-specific targeting at specific sites that allows for high-resolution diagnostic imaging and long-term patient-tailorable cancer therapy; while, minimizing side effects largely arising from non-targetability. This can be realized by harnessing exogenous remote stimuli, such as tissue-penetrative ultrasound, magnetic field, light, radiation, enable local activation therapy in deep tumors. A myriad of nanomedicines efficiently activated when the energy stimuli transformed into another type energy. review discusses control transformation targetable, efficient, therapy. Such ultrasonic, magnetic, photonic, radiative, radioactive mechanical, thermal, chemical, radiative to a variety modalities. The current article describes multimodal where serial cascade or multiple types occur. includes not only hyperthermia, radiation but also emerging thermoelectric, pyroelectric, piezoelectric therapies treatment. It illustrates resonance, fluorescence, computed tomography, photoluminescence, photoacoustic imaging-guided therapies. highlights afterglow eliminate autofluorescence sustained signal emission after excitation.
Language: Английский
Citations
21
Seminars in Nuclear Medicine, Journal Year: 2024, Volume and Issue: 54(4), P. 537 - 556
Published: July 1, 2024
Language: Английский
Citations
10
Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 15
Published: Feb. 3, 2025
Background The coexistence of lung cancer and pulmonary tuberculosis (TB) makes differential diagnosis even more complicated. purpose the study is to explore superiority [ 18 F]-NOTA-FAPI-04 PET/CT in distinguishing TB from malignant lesions accurately detecting inflammatory lymph nodes than F]-FDG PET/CT. Case summary Herein, we described a case report patient with both underwent Al[ positron emission tomography/computed tomography (PET/CT) determine staging. Additionally, literature review was conducted discuss potential clinical applications FAPI We reported 70-year-old man newly diagnosed squamous cell carcinoma avid uptake old right hilar (<1 cm) were not found on Al After 2 months follow-up, small node finally confirmed be inflammatory. Conclusion may perform better malignancy offer greater specificity for nodes.
Language: Английский
Citations
0
European Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 28, 2025
Language: Английский
Citations
0
Academic Radiology, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
Journal of Radioanalytical and Nuclear Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: March 18, 2025
Language: Английский
Citations
0
European Radiology, Journal Year: 2025, Volume and Issue: unknown
Published: March 27, 2025
Language: Английский
Citations
0
Clinical Nuclear Medicine, Journal Year: 2025, Volume and Issue: 50(5), P. 394 - 403
Published: April 4, 2025
Purpose: To evaluate the efficiency of 68 Ga-FAPI-04 PET (PET/MRI or PET/CT) for N and M staging in gastric carcinoma compare outcomes with histopathology contrast-enhanced computed tomography (CECT). Patients Methods: who had undergone PET/MRI PET/CT before treatment were retrospectively enrolled. Histopathology post lymphadenectomy was gold standard staging, while follow-up data reference overall outcomes. The diagnostic detecting regional lymph node involvement distant metastases compared to that CECT. Results: Sixty-two patients In 18 underwent lymphadenectomy, 532 nodes dissected. showed similar sensitivity, specificity, accuracy CECT (28.3% vs. 23.2%, 99.8% 99.3%, 86.5% 85.2%, all P > 0.05). Fifty-five metastasis, exhibited comparable CECT, sensitivity 83.6% versus 87.3%, specificity 100% 85.7%, 85.5% 87.1% (all Excluding 3 only abdominal 32 out 59 no significant differences between based on patient (100% 87.5%, 92.6% 96.3%, 96.6% 91.5%, >0.05). Notably, outperformed peritoneal, nodes, bone, liver, ovarian by visualizing more lesions greater lesion extent. Conclusions: exhibits performance patient-based cancer. However, it surpasses metastases.
Language: Английский
Citations
0
Journal of oncology diagnostic radiology and radiotherapy, Journal Year: 2025, Volume and Issue: 8(1), P. 29 - 35
Published: April 3, 2025
Purpose : To determine the diagnostic effectiveness of PET/CT with 68 Ga-FAPI in gastric cancer. Matreial and Methods :The study included 42 patients histologically confirmed All underwent 18 F-FDG. The accuracy methods was compared based on sensitivity specificity parameters detecting metastatic involvement regional lymph nodes. Data assessment conducted verified disease clinical follow-up data. Results is a more effective method for metastases nodes to Our results support potential improved diagnosis treatment planning
Language: Английский
Citations
0
Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 15
Published: April 10, 2025
To investigate the predictive value of pertinent metabolic parameters 18F-FDG PET/CT in relation to expression level human epidermal growth factor receptor 2 (HER2) patients with gastric cancer. The data was retrospectively acquired from 105 who had been pathologically diagnosed cancer prior treatment at our institution, including clinical data, laboratory test results, histological information, (including maximum standardized uptake (SUVmax), mean (SUVmean), peak (SUVpeak), SUVmax normalized by lean body mass (SULmax), SUVmean (SULmean), SUVpeak (SULpeak), tumor volume (MTV), and total lesion glycolysis (TLG)), HER2 level, January 2018 December 2022. correlation between examined, these measures for investigated. Among patients, 27 exhibited positive expression, while 78 demonstrated negative expression. Significant differences MTV TLG exhibiting (P < 0.05). best cut-off values were 20.3 cm³ 72.3 g, yielding accuracy rates 90.2% 89.0% predicting respectively. Our further grouped study shows that adenocarcinoma Lauren classification groups, significantly negatively correlated positivity. Notably, mixed tumors, AUC reached as high 0.85. correlations MTV/TLG status HER2-positive tumors are associated reduced burden, providing imaging biomarkers prognostic assessment. subgroup analysis subgroups revealed significant associations positivity, highlighting MTV's potential utility across subtypes supporting its role precision oncology.
Language: Английский
Citations
0