An adult chicken mortality case investigation: coinfection by Salmonella Indiana and Kentucky DOI Creative Commons

Qianzhe Cao,

Chenghao Jia,

Haiyang Zhou

et al.

Animal Diseases, Journal Year: 2025, Volume and Issue: 5(1)

Published: April 27, 2025

Abstract Coinfection, the simultaneous invasion of multiple pathogens into a single host, is critical but understudied area, especially in farm animal sector. We report unique and unusual fatal case coinfection with S . Indiana Kentucky, which has rarely been studied literature could hold potential importance for veterinary clinics. In silico analysis revealed that all isolates exhibited extensive multidrug resistance. By analyzing plasmids, two replicons, IncHI2 IncHI2A, were detected Indiana, whereas no plasmids Kentucky. Chicken embryo lethality assays demonstrated both Kentucky caused 100% mortality by third day post infection, significantly exceeding control strains. These findings emphasize high pathogenic these serovars, carries cdtB gene encoding typhoid toxin, further confirming its increased pathogenicity. Overall, our results underscore urgent need to improve biosecurity measures mitigate risk coinfections involving multidrug-resistant Salmonella strains poultry production environments.

Language: Английский

Ecological prevalence and genomic characterization of Salmonella isolated from selected poultry farms in Jiangxi province, China DOI

Xiaowu Jiang,

Abubakar Siddique,

Lexin Zhu

et al.

Poultry Science, Journal Year: 2025, Volume and Issue: 104(7), P. 105197 - 105197

Published: April 25, 2025

Language: Английский

Citations

0
An adult chicken mortality case investigation: coinfection by Salmonella Indiana and Kentucky DOI Creative Commons

Qianzhe Cao,

Chenghao Jia,

Haiyang Zhou

et al.

Animal Diseases, Journal Year: 2025, Volume and Issue: 5(1)

Published: April 27, 2025

Abstract Coinfection, the simultaneous invasion of multiple pathogens into a single host, is critical but understudied area, especially in farm animal sector. We report unique and unusual fatal case coinfection with S . Indiana Kentucky, which has rarely been studied literature could hold potential importance for veterinary clinics. In silico analysis revealed that all isolates exhibited extensive multidrug resistance. By analyzing plasmids, two replicons, IncHI2 IncHI2A, were detected Indiana, whereas no plasmids Kentucky. Chicken embryo lethality assays demonstrated both Kentucky caused 100% mortality by third day post infection, significantly exceeding control strains. These findings emphasize high pathogenic these serovars, carries cdtB gene encoding typhoid toxin, further confirming its increased pathogenicity. Overall, our results underscore urgent need to improve biosecurity measures mitigate risk coinfections involving multidrug-resistant Salmonella strains poultry production environments.

Language: Английский

Citations

0