Functional MRI responses to naturalistic stimuli are increasingly typical across early childhood

Developmental Cognitive Neuroscience, Journal Year: 2023, Volume and Issue: 62, P. 101268 - 101268

Published: June 15, 2023

While findings show that throughout development, there are child- and age-specific patterns of brain functioning, is also evidence for significantly greater inter-individual response variability in young children relative to adults. It currently unclear whether this increase functional "typicality" (i.e., similarity) a developmental process occurs across early childhood, what changes BOLD may be driving typicality. We collected fMRI data from 81 typically developing 4-8-year-old during passive viewing age-appropriate television clips asked increasing typicality age range. found the "increasing typicality" hypothesis was supported many regions engaged by viewing. Post hoc analyses showed priori ROIs related language face processing, strength group-average shared component activity increased with age, no concomitant decline residual signal or change spatial extent variability. Together, suggests similarity responses audiovisual stimuli an important feature childhood development.

Language: Английский

---

Individual differences in time-varying and stationary brain connectivity during movie watching from childhood to early adulthood: Age, sex, and behavioral associations

Developmental Cognitive Neuroscience, Journal Year: 2023, Volume and Issue: 63, P. 101280 - 101280

Published: July 17, 2023

Spatially remote brain regions exhibit dynamic functional interactions across various task conditions. While time-varying connectivity during movie watching shows sensitivity to content, stationary remains relatively stable videos. These findings suggest that and may represent different aspects of function. However, the relationship between individual differences in behavioral phenotypes elusive. To address this gap, we analyzed an open-access MRI dataset comprising participants aged 5-22 years, who watched two cartoon clips. We calculated regional activity, connectivity, examining associations with age, sex, assessments. Model comparison revealed was more sensitive age sex effects compared connectivity. The preferred models exhibited quadratic log or effects, indicative inverted-U shaped developmental patterns. In addition, females showed higher consistency activity than males. terms predictions, only demonstrated ability predict full-scale intelligence quotient. capture distinct phenotypes.

Language: Английский

---

Top-down attention shifts behavioral and neural event boundaries in narratives with overlapping event scripts

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 9, 2023

Understanding and remembering the complex experiences of everyday life relies critically on prior schematic knowledge about how events in our world unfold over time. How does brain construct event representations from a library scripts, activating specific script impact way that are segmented time? We developed novel set 16 audio narratives, each which combines one four location-relevant scripts (restaurant, airport, grocery store, lecture hall) with socially-relevant (breakup, proposal, business deal, meet cute), presented them to participants an fMRI study separate online study. Responses angular gyrus, parahippocampal subregions medial prefrontal cortex (mPFC) were driven by both location social information, showing these regions can track sequences multiple domains. For some stories primed attend two training listen for remember script-relevant episodic details. Activating location-related shifted timing subjective boundaries align changes this behavioral shift was mirrored neural responses, mPFC (identified using Hidden Markov Model) aligning rather than when primed. Our findings demonstrate dynamics actively modulated top-down goals, provide new insight into narrative constructed through activation temporally-structured knowledge.

Language: Английский

---

Inter-subject correlations of EEG reflect subjective arousal and acoustic features of music

Frontiers in Human Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Aug. 21, 2023

Background Research on music-induced emotion and brain activity is constantly expanding. Although studies using inter-subject correlation (ISC), a collectively shared analysis method, have been conducted, whether ISC during music listening represents the preferences of large population remains uncertain; additionally, it unclear which factors influence listening. Therefore, here, we aimed to investigate ISCs electroencephalography (EEG) represent preference for reflecting engagement or interest in music. Methods First, selected 21 pieces from Billboard Japan Hot 100 chart 2017, served as an indicator population. To ensure even representation, chose one piece every fifth song chart, spanning highly popular less ones. Next, recorded EEG signals while subjects listened music, they were asked evaluate four aspects (preference, enjoyment, frequency listening, arousal) each song. Subsequently, conducted by utilizing first three principal components EEG, correlated across extracted through component (CorrCA). We then explored with high that reflected had values. Additionally, employed cluster all impact emotions musical characteristics Results A significant distinction was noted between mean values 10 higher-ranked compared lower-ranked [ t (542) = −1.97, p 0.0025]. This finding suggests may correspond Furthermore, found variations observed among clusters identified analysis, along differences arousal levels. Moreover, (tonality tempo) differed clusters. indicates components, exhibit calculating values, both subjects’ levels specific Conclusion Subjects’ affect

Language: Английский

---

High performers demonstrate greater neural synchrony than low performers across behavioral domains

Imaging Neuroscience, Journal Year: 2024, Volume and Issue: 2, P. 1 - 17

Published: March 21, 2024

Abstract Heterogeneity in brain activity can give rise to heterogeneity behavior, which turn comprises our distinctive characteristics as individuals. Studying the path from however, often requires making assumptions about how similarity behavior scales with activity. Here, we expand upon recent work (Finn et al., 2020) proposes a theoretical framework for testing validity of such assumptions. Using intersubject representational analysis two independent movie-watching functional MRI (fMRI) datasets, probe brain-behavior relationships vary function behavioral domain and participant sample. We find evidence that, some cases, neural individuals is not correlated similarity. Rather, higher scores are more similar other high scorers whereas lower dissimilar everyone else. Ultimately, findings motivate extensive investigation both structure tacit assumption that people who behave similarly will demonstrate shared patterns

Language: Английский

---

Auditory areas are recruited for naturalistic visual meaning in early deaf people

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Sept. 17, 2024

Language: Английский

---

Neural and behavioral reinstatement jointly reflect retrieval of narrative events

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Abstract When recalling past events, patterns of gaze position and neural activity resemble those observed during the original experience. We hypothesized that these two phenomena, known as reinstatement reactivation, are linked through a common process underlies experiences memory retrieval. Here, we tested this proposal based on viewing recall narrative movie, which assessed fMRI, deep learningbased prediction, language modeling spoken recall. In line with key predictions, behavior adhered to same principles activity; it was event-specific, robust across individuals, generalized Additionally, gaze-dependent brain overlapped substantially tasks. Collectively, results suggest retrieval engages mechanisms direct our eyes natural vision, reflecting constraints within functional organization nervous system. Moreover, they highlight importance considering behavioral together in understanding remembering.

Language: Английский

---

Event segmentation in continuous, naturalistic videos from model-based, data-driven, and human perspectives

Published: Nov. 1, 2022

Human experience is characterised by an apparently continuous stream of information. However, when recalling our past, we commonly somewhat discrete episodes. Event segmentation has been suggested to provide a basis for episodic memory formation and recognition/recall. Previous work that event boundaries are reflected in shifts stable patterns neural activity across processing hierarchies, these can be detected using neuroimaging techniques. From different direction, recent series studies the domain human time perception have shown tracking as "surprise" network - perceptual or proxies successfully describes subjective reports on scale seconds minutes. This project aims understand how methods obtaining “event boundaries” perform relative human-provided annotations, situations life-like, naturalistic sensory stimulation. We compared estimated from neural-network-based model data-driven approach (Greedy State Boundary Search EEG data), against annotations 131 raters two inferential processes. In both methods, model-based performed similarly well, were indistinguishable provided at least ~89% cases examined. A random boundary generator was similar only approximately 13% cases. demonstrates potential reconcile fields through common foundation processes underlying segmentation.

Language: Английский

---

Brain state dynamics reflect emotion transitions induced by music

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: March 2, 2023

Abstract Our ability to shift from one emotion the next allows us adapt our behaviors a constantly-changing and often uncertain environment. Although previous studies have identified cortical subcortical regions involved in affective responding, no asked whether how these track represent transitions between different emotional states modulate their responses based on recent context. To this end, we commissioned new musical pieces designed systematically move participants through during fMRI. Using combination of data-driven (Hidden Markov Modeling) hypothesis-driven methods, show that spatiotemporal patterns activation along temporoparietal axis reflect music-evoked emotions. Furthermore, self-reported emotions subsequent neural response were sensitive context which music was heard. The findings highlight role temporal parietal brain not only processing low-level auditory signals, but linking changes signals with on-going, contextually-dependent responses.

Language: Английский

---

Asynchronous development of memory integration and differentiation influences temporal memory organization

Developmental Science, Journal Year: 2023, Volume and Issue: 27(2)

Published: Aug. 23, 2023

Abstract Adults remember items with shared contexts as occurring closer in time to one another than those associated different contexts, even when their objective temporal distance is fixed. Such memory biases are thought reflect within‐event integration and between‐event differentiation processes that organize events according contextual similarities differences, respectively. Within‐event hypothesized differentially rely on binding control processes, which may develop at ages. To test this hypothesis, 5‐ 12‐year‐olds adults ( N = 134) studied quartets of image pairs contained either the same scene (same‐context) or scenes (different‐context). Participants remembered same‐context by older childhood (7–9 years), whereas different‐context were farther apart early adolescence (10–12 years). The differential emergence these suggests emerge Research Highlights Children less likely use information (e.g., location) continuous experience memory, indicated biases. Biases reflecting (i.e., remembering elements a context together time) emerged late childhood. from adolescence. they distinct, yet complementary, support developmental improvements event organization.

Language: Английский

---