20 years of the default mode network: A review and synthesis

Neuron, Journal Year: 2023, Volume and Issue: 111(16), P. 2469 - 2487

Published: May 10, 2023

Language: Английский

---

Mapping patterns of thought onto brain activity during movie-watching

eLife, Journal Year: 2025, Volume and Issue: 13

Published: Jan. 10, 2025

Movie-watching is a central aspect of our lives and an important paradigm for understanding the brain mechanisms behind cognition as it occurs in daily life. Contemporary views ongoing thought argue that ability to make sense events ‘here now’ depend on neural processing incoming sensory information by auditory visual cortex, which are kept check systems association cortex. However, we currently lack how patterns thoughts map onto different when watch film, partly because methods sampling experience disrupt dynamics activity movie-watching. Our study established novel method mapping at moments does not time course or movie-watching experience. We found highlighted engagement with multi-sensory features film episodic features, regions cortex were more active subsequent memory movie was better—on other hand, periods intrusive distraction emerged within frontoparietal system reduced. These results highlight critical role play multi-modal provide evidence reducing films.

Language: Английский

---

Information flow across the cortical timescale hierarchy during narrative construction

Proceedings of the National Academy of Sciences, Journal Year: 2022, Volume and Issue: 119(51)

Published: Dec. 12, 2022

When listening to spoken narratives, we must integrate information over multiple, concurrent timescales, building up from words sentences paragraphs a coherent narrative. Recent evidence suggests that the brain relies on chain of hierarchically organized areas with increasing temporal receptive windows process naturalistic narratives. We hypothesized structure this cortical processing hierarchy should result in an observable sequence response lags between networks comprising during narrative comprehension. This study uses functional MRI estimate use intersubject cross-correlation analysis capture network connectivity driven by shared stimulus. found fixed lags-on scale several seconds-starting early auditory areas, followed language attention network, and lastly default mode network. gradient is consistent across eight distinct stories but absent data acquired rest or using scrambled story stimulus, supporting our hypothesis construction gives rise internetwork lags. Finally, build simple computational model for neural dynamics underlying nested features. Our simulations illustrate how gradual accumulation within boundaries linguistic events, accompanied increased activity at each level hierarchy, can give observed lag gradient.

Language: Английский

---

Evidence That Event Boundaries Are Access Points for Memory Retrieval

Psychological Science, Journal Year: 2023, Volume and Issue: 34(3), P. 326 - 344

Published: Jan. 3, 2023

When recalling memories, we often scan information-rich continuous episodes, for example, to find our keys. How does brain access and search through those memories? We suggest that high-level structure, marked by event boundaries, guides us this process: In computational model, memory scanning is sped up skipping ahead the next boundary upon reaching a decision threshold. adult Mechanical Turk workers from United States, used movie (normed boundaries; Study 1,

Language: Английский

---

The ‘L-factor’: Language as a transdiagnostic dimension in psychopathology

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2024, Volume and Issue: 131, P. 110952 - 110952

Published: Jan. 26, 2024

Thoughts and moods constituting our mental life incessantly change. When the steady flow of this dynamics diverges in clinical directions, possible pathways involved are captured through discrete diagnostic labels. Yet a single vulnerable neurocognitive system may be causally psychopathological deviations transdiagnostically. We argue that language viewed as integrating cortical functions is best current candidate, whose forms breakdown along its different dimensions then manifest symptoms – from prosodic abnormalities rumination depression to distortions speech perception verbal hallucinations, meaning content delusions, or disorganized formal thought disorder. Spontaneous connected provides continuous objective readouts generating highly accessible bio-behavioral marker with potential revolutionizing neuropsychological measurement. This argument turns into transdiagnostic ‘L-factor’ providing an analytical mechanistic substrate for previously proposed latent general factors psychopathology (‘p-factor’) cognitive functioning (‘c-factor’). Together immense practical opportunities afforded by rapidly advancing natural processing (NLP) technologies abundantly available data, suggests new era translational psychiatry, which both rethought together.

Language: Английский

---

High-Order Areas and Auditory Cortex Both Represent the High-Level Event Structure of Music

Journal of Cognitive Neuroscience, Journal Year: 2022, Volume and Issue: 34(4), P. 699 - 714

Published: Jan. 11, 2022

Abstract Recent fMRI studies of event segmentation have found that default mode regions represent high-level structure during movie watching. In these regions, neural patterns are relatively stable events and shift at boundaries. Music, like narratives, contains hierarchical (e.g., sections composed phrases). Here, we tested the hypothesis brain activity in reflect music. We used to record from 25 participants (male female) as they listened a continuous playlist 16 musical excerpts additionally collected annotations for by asking separate group mark when meaningful changes occurred each one. then identified temporal boundaries between using hidden Markov model compared location human annotations. multiple with significant matches observer-identified boundaries, including auditory cortex, medial prefrontal parietal angular gyrus. From results, conclude both higher-order sensory areas contain information relating Moreover, this study overlap previous perception movies audio network.

Language: Английский

---

Developmental changes in story-evoked responses in the neocortex and hippocampus

eLife, Journal Year: 2022, Volume and Issue: 11

Published: July 5, 2022

How does the representation of naturalistic life events change with age? Here, we analyzed fMRI data from 414 children and adolescents (5-19 years) as they watched a narrative movie. In addition to changes in degree inter-subject correlation (ISC) age sensory medial parietal regions, used novel measure (between-group ISC) reveal age-related shifts responses across majority neocortex. Over course development, brain became more discretized into stable coherent shifted earlier time anticipate upcoming perceived event transitions, measured behaviorally an age-matched sample. However, hippocampal boundaries actually decreased age, suggesting shifting division labor between episodic encoding processes schematic representations ages 5 19.

Language: Английский

---

Toward an integrative account of internal and external determinants of event segmentation

Psychonomic Bulletin & Review, Journal Year: 2023, Volume and Issue: 31(2), P. 484 - 506

Published: Sept. 12, 2023

Language: Английский

---

Synchronous high-amplitude co-fluctuations of functional brain networks during movie-watching

Imaging Neuroscience, Journal Year: 2023, Volume and Issue: 1, P. 1 - 21

Published: Oct. 19, 2023

Abstract Recent studies have shown that functional connectivity can be decomposed into its exact frame-wise contributions, revealing short-lived, infrequent, and high-amplitude time points referred to as “events.” Events contribute disproportionately the time-averaged pattern, improve identifiability brain-behavior associations, differences in their expression been linked endogenous hormonal fluctuations autism. Here, we explore characteristics of events while subjects watch movies. Using two independently-acquired imaging datasets which participants passively watched movies, find synchronize across individuals based on level synchronization, categorized three distinct classes: those at boundaries between during do not all. We boundary events, compared other categories, exhibit greater amplitude, co-fluctuation patterns, temporal propagation. show underlying events1 is a specific mode involving activation control salience systems alongside deactivation visual systems. movie, hand, display pattern time-locked movie stimulus. Finally, found subjects’ time-varying brain networks are most similar one another these synchronous events.

Language: Английский

---

More than a moment: What does it mean to call something an ‘event’?

Psychonomic Bulletin & Review, Journal Year: 2023, Volume and Issue: 30(6), P. 2067 - 2082

Published: July 5, 2023

Language: Английский

---