Sustained EEG responses to rapidly unfolding stochastic sounds reflect Bayesian inferred reliability tracking DOI Creative Commons
Sijia Zhao, Benjamin Skerritt-Davis, Mounya Elhilali

et al.

Progress in Neurobiology, Journal Year: 2024, Volume and Issue: unknown, P. 102696 - 102696

Published: Dec. 1, 2024

How does the brain track and process rapidly changing sensory information? Current computational accounts suggest that our sensations decisions arise from intricate interplay between bottom-up signals constantly expectations regarding statistics of surrounding world. A significant focus recent research is determining which statistical properties are tracked by as it monitors rapid progression Here, combining EEG (three experiments N≥22 each) modelling, we examined how processes stochastic sound sequences simulate key aspects dynamic environments. Passively listening participants were exposed to structured tone-pip arrangements contained transitions a range patterns. Predictions guided Bayesian predictive inference model. We demonstrate listeners automatically unfolding sounds, even when these irrelevant behaviour. Transitions sequence patterns drove an increase sustained response. This was observed distributional statistics, in situations where behavioural detection at floor. These observations modulation response reflects belief updating within brain. By establishing connection outputs model responses, dynamics transition-related responses align with tracking "precision" - confidence or reliability assigned predicted signal shedding light on brain's mechanisms its dynamics.

Language: Английский

Muscarinic receptors at the auditory thalamocortical circuits and relevance to hearing DOI
Shivani Shivani, Avinash Wadkar, Srinivasa P. Kommajosyula

et al.

Life Sciences, Journal Year: 2025, Volume and Issue: 369, P. 123522 - 123522

Published: March 3, 2025

Language: Английский

Citations

0
An active inference account of stuttering behavior DOI Creative Commons
Evan Usler

Frontiers in Human Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 3, 2025

This paper presents an interpretation of stuttering behavior, based on the principles active inference framework. Stuttering is a neurodevelopmental disorder characterized by speech disfluencies such as repetitions, prolongations, and blocks. The inference, theory predictive processing sentient can be used to conceptualize disruption in perception-action cycling underlying production. proposed here posits that arises from aberrant sensory precision prediction error dynamics, inhibiting syllable initiation. Relevant this theory, two hypothesized mechanisms are proposed: (1) mistiming (2) excessive attentional focus. Both highlight role neural oscillations, error, hierarchical integration framework also explains contextual variability behaviors, including adaptation effects fluency-inducing conditions. Reframing synaptopathy integrates neurobiological, psychological, behavioral dimensions, suggesting disruptions precision-weighting mediated neuromodulatory systems. perspective provides unified account sets stage for innovative research therapeutic approaches.

Language: Английский

Citations

0
Multimodal mapping of macaque monkey somatosensory cortex DOI Creative Commons
Meiqi Niu, Lucija Rapan, Seán Froudist‐Walsh

et al.

Progress in Neurobiology, Journal Year: 2024, Volume and Issue: 239, P. 102633 - 102633

Published: June 1, 2024

The somatosensory cortex is a brain region responsible for receiving and processing sensory information from across the body structurally functionally heterogeneous. Since chemoarchitectonic segregation of cerebral can be revealed by transmitter receptor distribution patterns, using quantitative multireceptor architectonical analysis, we determined number extent distinct areas macaque cortex. We identified three architectonically cortical entities within primary (i.e., 3bm, 3bli, 3ble), four anterior parietal 3am, 3al, 1 2) six subdivisions S2l, S2m, PVl, PVm, PRl PRm) lateral fissure. provide an ultra-high resolution 3D atlas in stereotaxic space, which integrates cyto- architectonic features areas. Multivariate analyses fingerprints clusters based on degree (dis)similarity their architecture. Each these associated with levels processing, further demonstrating that functional underpinned differences molecular organization.

Language: Английский

Citations

3
Physiological properties of auditory neurons responding to omission deviants in the anesthetized rat DOI Creative Commons
Ana B. Lao-Rodríguez, David Pérez-González, Manuel S. Malmierca

et al.

Hearing Research, Journal Year: 2024, Volume and Issue: 452, P. 109107 - 109107

Published: Aug. 28, 2024

The detection of novel, low probability events in the environment is critical for survival. To perform this vital task, our brain continuously building and updating a model outside world; an extensively studied phenomenon commonly referred to as predictive coding. Predictive coding posits that extracting regularities from generate predictions. These predictions are then used supress neuronal responses redundant information, filtering those inputs, which automatically enhances remaining, unexpected inputs. We have recently described ability auditory neurons about expected sensory inputs by detecting their absence oddball paradigm using omitted tones deviants. Here, we individual presenting sequences repetitive pure tones, both random periodic omissions, presented at fast slow rates inferior colliculus cortex anesthetized rats. Our goal was determine whether feature-specific dependence these exists. Results showed could be detected high (8 Hz) repetition (2 Hz), with being more robust non-lemniscal pathway.

Language: Английский

Citations

1
Sustained EEG responses to rapidly unfolding stochastic sounds reflect Bayesian inferred reliability tracking DOI Creative Commons
Sijia Zhao, Benjamin Skerritt-Davis, Mounya Elhilali

et al.

Progress in Neurobiology, Journal Year: 2024, Volume and Issue: unknown, P. 102696 - 102696

Published: Dec. 1, 2024

How does the brain track and process rapidly changing sensory information? Current computational accounts suggest that our sensations decisions arise from intricate interplay between bottom-up signals constantly expectations regarding statistics of surrounding world. A significant focus recent research is determining which statistical properties are tracked by as it monitors rapid progression Here, combining EEG (three experiments N≥22 each) modelling, we examined how processes stochastic sound sequences simulate key aspects dynamic environments. Passively listening participants were exposed to structured tone-pip arrangements contained transitions a range patterns. Predictions guided Bayesian predictive inference model. We demonstrate listeners automatically unfolding sounds, even when these irrelevant behaviour. Transitions sequence patterns drove an increase sustained response. This was observed distributional statistics, in situations where behavioural detection at floor. These observations modulation response reflects belief updating within brain. By establishing connection outputs model responses, dynamics transition-related responses align with tracking "precision" - confidence or reliability assigned predicted signal shedding light on brain's mechanisms its dynamics.

Language: Английский

Citations

1