An analysis of outcomes in respiratory therapy in patients with acute stroke

S S Korsakov Journal of Neurology and Psychiatry, Journal Year: 2018, Volume and Issue: 118(6), P. 37 - 37

Published: Jan. 1, 2018

To evaluate the effectiveness of mechanical ventilation in patients with stroke.A retrospective analysis 520 acute cerebrovascular diseases requiring lung was performed.In 44,6% cases, reason for transferring to a worsening neurological status; 69,1% underwent prolonged respiratory support period 3 days 2 weeks. 54.2% died. Half surviving had severe disability. In older age group, risk an unfavorable outcome increased. Mortality increased and rehabilitation potential decreased increase duration care. The results point need create unified concept carrying out artificial lungs groups taking into account clinical economic feasibility.Цель исследования. Оценить эффективность искусственной вентиляции легких (ИВЛ) у пациентов с острым нарушением мозгового кровообращения (ОНМК). Материал и методы. Проведен ретроспективный анализ историй болезни ОНМК, которым потребовалось выполнение ИВЛ. Результаты заключение. Причиной перевода на ИВЛ в случаев являлось ухудшение неврологического статуса. В проводилась пролонгированная респираторная поддержка сроком от сут до нед. Летальный исход наступил 54,2% пациентов, находившихся У половины выживших больных имела место тяжелая инвалидизация. старшей возрастной группы был выявлен более высокий риск неблагоприятного исхода. С увеличением возраста длительности респираторной поддержки возрастала летальность снижался реабилитационный потенциал. Полученные данные указывают необходимость создания единой концепции проведения старших возрастных групп учетом клинической экономической целесообразности.

Language: Русский

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MORTALITY DYNAMICS AND LIFE EXPECTANCY OF POPULATION OF ARCTIC/SUBARCTIC REGION OF THE RUSSIAN FEDERATION IN 1999-2014

Ekologiya Cheloveka (Human Ecology), Journal Year: 2017, Volume and Issue: 24(9), P. 48 - 58

Published: Sept. 15, 2017

This article presents the results of analysis mortality dynamics among population 9 territories Arctic and Subarctic regions, using linear regression technique. All-cause reduction was significantly greater in 4 country. These regions were: Murmansk region Komi Republic (for females), Archangelsk both sexes) Sakha (Yakutia) males). The following displayed which close to national averages or less: YaNAO, KhMAO Magadan region. Mortality rates males declined faster than that females. Relatively lower indicators YaNAO could likely be attributed migration mid-latitude with accumulated burden northern pathology. tendencies from leading death causes (diseases circulatory system, respiratory diseases, external causes) are averages. most strongly reduced brain strokes, myocardial infarction death. can described as relatively positive on whole, except for "other diseases system" category, where exceeded average twice particular years. Life expectancy is Russia, two autonomous - Khanty-Mansiisky Yamalo-Nenetsky, life higher by 1.7 2.6 years 0.4 0.7 females, respectively. situation Nenetsky Chukotsky Autonomous Regions remains unclear because possible inaccuracy primary data.

Language: Английский

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Health-related R&D priorities until 2030: Russian experience

foresight, Journal Year: 2017, Volume and Issue: 19(5), P. 501 - 510

Published: Aug. 1, 2017

Purpose The aim of this paper is to present results a foresight study on identifying priorities for health-related research and development (R&D) in Russia the period until 2030. Design/methodology/approach Research were identified through consistent integrated expert analysis evaluation subject area, i.e. biomedical preceding medical technologies. Findings Key global national trends R&D sector related areas (medicine health) identified. According experts, following markets have best prospects Russia: regenerative medicine, biodegradable other biocompatible materials, diagnostic systems, implants, surgical equipment, targeted delivery systems non-invasive visualisation systems. Entering these requires providing support areas: promising drug candidates, molecular diagnostics, profiling mechanisms human diseases, cell technologies (therapies), new materials (biomimetics other), bioelectronic, bioimaging biosensors genome databases. Practical implications Regularly updating necessary prerequisite successful science technology countries, innovative companies academic institutions. Allocation (always limited) financial resources basis such priority-setting exercises’ evidence adherence scientific planning principles. Combined with monitoring tools, priority setting must become an integral component Russia’s innovation policy. Originality/value This first-ever presentation Russian experience sphere. Global contexts are described; biggest potential

Language: Английский

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APPLICATION OF ULTRASOUND ASSESSMENT OF LEFT VENTRICULAR CARDIAC STRAIN IN CARDIOLOGY

Ulyanovsk Medico-biological Journal, Journal Year: 2020, Volume and Issue: 3, P. 28 - 43

Published: Sept. 28, 2020

Cardiovascular diseases (CVDs) remain one of the most urgent health problems worldwide. These cover a large population groups and affect all age regardless gender. Heart failure (HF), as natural complication CVDs, is not an exclusive disease elderly people. There are numerous complex pathophysiological mechanisms that operate cause HF. include traditional cardiovascular risk factors (arterial hypertension, dyslipidemia, overweight), low living standards, problematic access to system due socio-economic inequalities. Special attention currently paid problem early heart diagnosis. So, today medical community discussing possibility using such non-invasive technique ultrasound study cardiac strain. Currently, affordable highly informative for diagnosis HF manifestations. The authors consider issue only clinical, but also prognostic significance strain indicators in patients with CVD This review highlights main issues assessment, advantages limitations. studied publicly available literature analyzed promising directions application modern cardiology. For literary analysis, resources PubMed, eLibrary, CyberLeninka, MedLine, Google Scholar, Elsevier were used. Keywords: failure, echocardiography, strain, risk. Сердечно-сосудистые заболевания (ССЗ) остаются одной из наиболее актуальных проблем здравоохранения во всем мире. Они охватывают обширную группу населения и затрагивают все возрастные категории вне зависимости от пола. Сердечная недостаточность (СН), как закономерное осложнение большинства ССЗ, не является болезнью исключительно пожилых людей. Существуют многочисленные сложные патофизиологические механизмы, которые реализуются возраста приводят к СН. включают традиционные факторы сердечно-сосудистого риска (артериальную гипертензию, дислипидемию, избыточную массу тела), низкий уровень жизни населения, а также неоптимальный доступ системам из-за социально-экономического неравенства. Особое внимание в настоящее время уделяется проблеме ранней диагностики Так, сегодня медицинское сообщество обсуждает возможность использования такой неинвазивной методики, ультразвуковое исследование (УЗИ), целях изучения деформации миокарда. УЗИ – это доступная высокоинформативная методика для проявлений Обсуждается вопрос только клинической, но прогностической значимости показателей миокарда у больных с ССЗ В настоящем обзоре освещены основные вопросы оценки миокарда, преимущества, ограничения этой методики. На основании полученных открытых источниках литературы данных проведен анализ перспективных направлений применения методики современной кардиологии. Для литературного поиска были использованы ресурсы поисковых систем Elsevier. Ключевые слова: сердечная недостаточность, эхокардиография, деформация сердечно-сосудистый риск.

Language: Русский

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Experimental modeling of myocardial infarction in old rats

Pacific Medical Journal, Journal Year: 2022, Volume and Issue: 2, P. 72 - 74

Published: June 23, 2022

The results of modeling acute myocardial infarction on 20 male Wistar rats aged 24 months are presented. Ischemic effect is carried out by local injection 1.5% sclerosant ethoxysclerol (0.25 ml) into the thickness myocardium under general anesthesia using non-traumatic needle with silicone coating, which allows to simulate minimal invasive animal's body, trauma, little duration intervention, low mortality, frequency complications and absence systemic action drugs.

Language: Английский

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Clinical study protocol on assessment of quality of medical care and clinical prognosis in patients who underwent myocardial revascularization accounting modifiable risk factors

Siberian Journal of Clinical and Experimental Medicine, Journal Year: 2024, Volume and Issue: 39(4), P. 150 - 161

Published: Oct. 10, 2024

Introduction . Every year in Russia, the number of people who have undergone cardiac surgery exceeds 600 thousand. Among them, anemia occurs 30-70% cases, and cognitive dysfunction is noted 20–80% cases. Anemia increases risk death 4-fold within a year, 5-fold stent thrombosis, 1.3–fold recurrence acute coronary syndrome 2-fold bleeding, worsens quality life, status compliance. Unresolved problems managing medical care for specialized patients are associated with insufficient coupling components clinical sociopsychological interaction, taking into account modifiable factors, irrational use limited industry resources distributed according to quota mechanism. Patient-centered digital systems contribute improving life patients, optimizing healthcare resources. Aim : To evaluate parameters prognosis underwent myocardial revascularization, an expanded range including anemia, depression, using developed intelligent data collection system. Material Methods A prospective cohort study 300 adult revascularization planned 12 months 3 groups (depending on consent technical feasibility information system (CIS): 1 group will undergo questionnaires behavioral training online through CIS; 2 only not CIS. There face-to-face visits doctor (6 months), at which following endpoints be evaluated: outcomes; rehabilitation; patient-reported experience indicator (PREM). Validated authored self-questionnaires used.

Language: Английский

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Analysis of Immunobiochemical Parameters in Overweight People in Assessing the Risk of Cardiovascular Diseases

Bulletin of Experimental Biology and Medicine, Journal Year: 2023, Volume and Issue: 174(4), P. 446 - 450

Published: Feb. 1, 2023

Language: Английский

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Hygienic assessment of pesticides and chemical fertilizers use in agriculture of the Republic of Tatarstan

Kazan medical journal, Journal Year: 2017, Volume and Issue: 98(1), P. 116 - 121

Published: Feb. 10, 2017

AIM. Hygienic assessment of pesticides and chemical fertilizers use on the background other technogenic environmental components influence determination their contribution to non-infectious morbidity adult population. METHODS. The analysis included parameters impact air, water bodies, soil including those reflecting resource-saving tillage technologies. connection between characterizing primary total prevalence endocrine, cardiovascular, respiratory diseases population Republic Tatarstan in 2000-2014 was analyzed. RESULTS. During analyzed period quantitative qualitative characteristics have changed dramatically republic: area gross volume pesticides, primarily, herbicides, stocks range products increased. Over 15 years republic has increased by 2.3 times, consumption - 1.9 herbicides 2.85 times. Due active implementation technologies into agriculture ratio glyphosate Among incidence cancer cardiovascular endocrine 25.7% among people working age even more (by 39.1%, p 0.01) elder people. areas correlated with overall diseases. 32.5 100% direct significant environment objects known disease classes is associated use. CONCLUSION. high density (55.6 people/sq.km), development oil, mechanical industries agricultural sector, accompanied increase hydrosphere lithosphere, further expansion minimal zero technology, occupying nowadays half territory, should be performed great caution constant laboratory epidemiologic monitoring.

Language: Английский

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Level of aurathrenomedullin in chronic heart failure of ischemic genesis: associations with clinical manifestations

Bulletin of Siberian Medicine, Journal Year: 2019, Volume and Issue: 18(3), P. 81 - 89

Published: Oct. 27, 2019

Objective. To identify and evaluate the relationship between level of proadrenomedullin clinical anamnestic data patients with chronic heart failure ischemic genesis. Materials methods . 240 men forms coronary disease (mean age 55.9 [43; 63] years) past Q-forming myocardial infarction were examined. Of these, 110 had preserved left ventricular ejection fraction (group 1) 130 dilatation a low 2). In all MR-proADM in blood serum was determined. Results control group, 0.49 [0.18; 0.58] nmol /l. meantime, it statistically significantly higher studied groups than group (p < 0.001 p 0.001, respectively). And fraction, (1.72 [1.56; 1.98] nmol/l 0.89 [0.51; 1.35] nmol/l, respectively, 0.038). The study demonstrated presence significant associations severity exertional angina pectoris as well constant form atrial fibrillation levels systolic diastolic pressure. Conclusion is new promising marker, which will be possible to use diagnostic standard for assessing effectiveness treatment cardiac patients.

Language: Английский

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PRIMARY DISABILITY OF THE ADULT POPULATION DUE TO DISEASES OF THE CIRCULATORY SYSTEM

Siberian Journal of Life Sciences and Agriculture, Journal Year: 2021, Volume and Issue: 13(5), P. 205 - 225

Published: Oct. 29, 2021

Background. Diseases of the circulatory system continue to hold a leading position as cause morbidity in population. Emerging сomplications diseases are associated with persistent impairment health and Work capacity which is basis for determining disability. Purpose. An in-depth analysis primary disability indicators adult population Moscow due system. Materials methods. The object study was “Information on medical social examination persons aged 18 over” (form 7-social security 2013-2019). Research methods: documentary, copy data, statistical graphic. Statistical data processing performed using Statistica 10 SAS JMP 11 software package. Results. In nosological structure CVD, first ranking place taken by peaple who were newly recognized disabled (PNRD) cerebrovascular (CVD), second – PNRD coronary heart disease, third “Other system“. Men elderly prevailed age-sex disability. greatest differences between contingents revealed terms proportion various types activity limitations degree, predominantly took among CVD. prevailing group III group. Conclusion. features dynamics advisable use when planning measures improve effectiveness rehabilitation people this socially significant pathology.

Language: Английский

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