Comparative Determination of Immuno-Biochemical Indicators in Patients with Cardiovascular Diseases

Физиология человека, Journal Year: 2023, Volume and Issue: 49(2), P. 74 - 80

Published: March 1, 2023

The development of new diagnostic methods for the prediction, treatment and prevention cardiovascular diseases is an urgent task. purpose this study was to compare specific immunological clinical-biochemical markers in patients with diseases. In accordance established diagnosis, three groups participants were examined – a total 139 people, including control group. first group hypertension, second diagnosis hypertension coronary heart disease. these patients, biochemical parameters blood antibodies β-endorphin, bradykinin, histamine, dopamine, serotonin, traditionally used practice, compared. Deviations 38–65% content dopamine serotonin found compared control. A correlation hematological found. direct relationship level AST activity (r = 0.4, p 0.05), histamine ESR concentration 0.6, 0.05). Thus, practical significance combined use tests assessing violation homeostasis body disease has been established. Monitoring additional indicators assess increases degree prognosis severity pathology.

Language: Английский

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STUDYING OF LONG-TERM RESULTS OF PREVENTION HELP TO PATIENTS OF WORKING AGE WITH PARTICIPATION OF ТНЕ NURSING STAFF

Russian Medicine, Journal Year: 2019, Volume and Issue: 25(3), P. 143 - 145

Published: June 15, 2019

The RF currently work a nurse can be considered as new type of professional activity medical, psychological, pedagogical and socio-legal nature, the purpose which is to preservation, enhancement restoration health patients. Purpose - study received remote results preventive nursing activities among working-age patients with arterial hypertension. Material methods. Studied observation questioning students hypertensive aged 35-65 years in school prevention results. Researched group hypertension (AH), were training classes on prophylaxis recurrence complications AH healthy lifestyle programme using process without it shows efficiency these activities. Conclusion. use educational technology “Nursing process” showed their effective influence enhancing treatment occurrence relapses AH.

Language: Английский

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Pharmacoepidemiological analysis of the effect of lipid-lowering therapy on cardiovascular mortality in the regions of the Russian Federation

Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice, Journal Year: 2022, Volume and Issue: 2, P. 45 - 54

Published: Aug. 2, 2022

Objectives . Cardiovascular diseases (CVD) are one of the leading causes death worldwide, including Russia. According to data obtained from ESSE-RF study, most common risk factor for development CVD is high level cholesterol. At same time, among drugs that lower cholesterol levels, statins studied. The main aim study was conduct a retrospective pharmacoepidemiological assess effect hypolipidemic therapy on overall and cardiovascular mortality in regions Russian Federation. Methods first stage, indicators population, 2012–2018 were analyzed 84 subjects time period analysis determined by timing implementation Federal project "Combating Diseases". Next, we frequency prescribing lipid-lowering doses Federation 2014– 2018, according IMS Health 2 market segments (preferential hospital). number patients receiving high-dose (HDS) (atorvastatin 40 80 mg, rosuvastatin 20 mg) calculated based sales volumes natural terms. Results Based mortality, all divided into 3 groups: high, medium moderate mortality. In high-mortality group, HDS consumption per patient averaged 4.45 100,000 moderate-mortality 19.39 patients, 21.51 patients. Conclusions results showed there relationship between use These may indicate effectiveness real practice.

Language: Английский

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Epidemiological Analysis of the Frequency of Acute Respiratory Diseases and Diseases of the Circulatory System Using Medical Information Technologies

Epidemiology and Vaccinal Prevention, Journal Year: 2021, Volume and Issue: 20(3), P. 45 - 52

Published: July 20, 2021

Relevance . Acute respiratory diseases (ARD) refer to mass infectious diseases, cause significant economic damage by provoking the development of circulatory system, and seasonal incidence ARI is a predictor mortality from cardiovascular which requires timely statistical accounting using medical information system (MIS). The aim study was quantitatively assess risk exposure ARIs on occurrence data processing MIS. Materials methods epidemiological carried out in design retrospective analytical cohort cases temporary disability adult population, with identification causal relationship MIS, provides primary collection, storage, selection grouping patients, subsequent calculations relative its 95% confidence interval. Results discussion Using 88,735 incapacity for work issued period 2014 2019 were recorded analyzed. Thanks reference architecture sample patients acute infections out, their according rate into main control groups. group (frequently ill) represented who ill more than 3 times per season, (rarely 1 2 season. consisted 4,980 1,461 3519 group. A statistically revealed between angina pectoris documented spasm (I20.1), chronic ischemic heart disease (I25.1), cerebrovascular (I67.9), atherosclerosis arteries extremities (I70.2), phlebitis thrombophlebitis (I80), varicose veins lower (I83), as well hemorrhoids (I84). Conclusions introduction practice has predominantly architecture, will optimize surveillance non-infectious registration disability, hospitalization taking effective anti-epidemic preventive measures.

Language: Английский

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Echocardiographic assessment of right ventricular systolic function in acute inferior myocardial infarction

Medical alphabet, Journal Year: 2021, Volume and Issue: 28, P. 24 - 30

Published: Dec. 2, 2021

Purpose . To assess the systolic function of right ventricle in patients with acute inferior myocardial infarction after percutaneous coronary intervention according to results echocardiographic examination. Materials and methods Echocardiographic data 72 working-age were analyzed. RV was assessed by TAPSE, S’TV, longitudinal strain RV. Results In 37.5% AMI wall, 96% cases ECG (elevation ST segment first hours disease) 4% echocardiography (impaired local contractility PCI), diagnosed. After PCI, medians TAPSE S’TV obtained M- pulsed- wave modes tissue Doppler between groups isolated (n=45) involvement (n=27) did not differ from control. Analysis all walls three segments its free wall speckle tracking technology demonstrates large changes deformity a combination both ventricles. The minimum AMI, statistically significantly different control group, observed at basal level interventricular septum. Changes parameters apical present only Conclusion According examination M-mode pulsed-wave mode Doppler, ventricular an course week corresponds normal values. Using technology, global is restored, remaining below recommended norms values group variants. median septal had value (-9 -12%) combined lesions

Language: Английский

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