Scientific Reports,
Год журнала:
2021,
Номер
11(1)
Опубликована: Июнь 7, 2021
Abstract
Eveningness,
a
preference
for
later
sleep
and
rise
times,
has
been
associated
with
number
of
negative
outcomes
in
terms
both
physical
mental
health.
A
large
body
evidence
links
eveningness
to
Major
Depressive
Disorder
(MDD).
However,
date,
quantifying
this
association
is
limited.
The
current
meta-analysis
included
43
effect
sizes
from
total
27,996
participants.
Using
random-effects
model
it
was
demonstrated
that
small
size
(Fisher’s
Z
=
−
2.4,
95%
CI
[−
0.27.
0.21],
p
<
0.001).
Substantial
heterogeneity
between
studies
observed,
meta-regression
analyses
demonstrating
significant
mean
age
on
the
diurnal
depression.
There
also
potential
publication
bias
as
assessed
by
visual
inspection
funnel
plots
Egger’s
test.
depression
magnitude
heterogenous.
better
understanding
mechanistic
underpinnings
linking
suitably
powered
prospective
allow
causal
inference
are
required.
Biomolecules,
Год журнала:
2021,
Номер
11(4), С. 487 - 487
Опубликована: Март 24, 2021
The
circadian
rhythm
plays
a
fundamental
role
in
regulating
biological
functions,
including
sleep-wake
preference,
body
temperature,
hormonal
secretion,
food
intake,
and
cognitive
physical
performance.
Alterations
can
lead
to
chronic
disease
impaired
sleep.
rhythmicity
human
beings
is
represented
by
complex
phenotype.
Indeed,
over
24-h
period,
person's
preferred
time
be
more
active
or
sleep
expressed
the
concept
of
morningness-eveningness.
Three
chronotypes
are
distinguished:
Morning,
Neither,
Evening-types.
Interindividual
differences
need
considered
reduce
negative
effects
disruptions
on
health.
In
present
review,
we
examine
bi-directional
influences
rest-activity
cycle
pathologies
disorders.
We
analyze
main
characteristics
three
chronotypes.
Depression and Anxiety,
Год журнала:
2019,
Номер
36(10), С. 975 - 986
Опубликована: Июль 26, 2019
Background
Actigraphy
may
provide
a
more
valid
assessment
of
sleep,
circadian
rhythm
(CR),
and
physical
activity
(PA)
than
self-reported
questionnaires,
but
has
not
been
used
widely
to
study
the
association
with
depression/anxiety
their
clinical
characteristics.
Methods
Fourteen-day
actigraphy
data
359
participants
current
(n
=
93),
remitted
176),
or
no
90)
composite
international
diagnostic
interview
diagnoses
were
obtained
from
Netherlands
Study
Depression
Anxiety.
Objective
estimates
included
sleep
duration
(SD),
efficiency,
relative
amplitude
(RA)
between
day-time
night-time
activity,
mid
on
free
days
(MSF),
gross
motor
(GMA),
moderate-to-vigorous
PA
(MVPA).
Self-reported
measures
insomnia
rating
scale,
SD,
MSF,
metabolic
equivalent
total,
MVPA.
Results
Compared
controls,
individuals
had
significantly
different
objective,
self-reported,
CR:
lower
GMA
(23.83
vs.
27.4
milli-gravity/day,
p
.022),
MVPA
(35.32
47.64
min/day,
.023),
RA
(0.82
0.83,
.033).
In
contrast,
differed
people
compared
those
without
disorders;
reported
both
shorter
longer
SD
insomnia.
More
depressive/anxiety
symptoms
number
associated
larger
disturbances
measures.
Conclusion
provides
ecologically
information
CR,
that
enhances
questionnaires.
As
severe
comorbid
forms
showed
lowest
most
CR
disruptions,
potential
for
adjunctive
behavioral
chronotherapy
interventions
should
be
explored,
as
well
monitor
treatment
response
such
interventions.
Frontiers in Neuroscience,
Год журнала:
2022,
Номер
16
Опубликована: Авг. 10, 2022
The
circadian
rhythm
is
crucial
for
physiological
and
behavioral
functions.
Chronotype,
which
represents
individual
preferences
activity
performance,
associated
with
human
health
issues,
particularly
psychiatric
disorders.
This
narrative
review,
focuses
on
the
relationship
between
chronotype
mental
disorders,
provides
an
insight
into
potential
mechanism.
Recent
evidence
indicates
that
(1)
evening
a
risk
factor
depressive
disorders
substance
use
whereas
morning
protective
factor.
(2)
Evening
individuals
bipolar
disorder
tend
to
have
more
severe
symptoms
comorbidities.
(3)
only
related
anxiety
symptoms.
(4)
schizophrenia
remains
unclear,
despite
increasing
their
link.
(5)
significantly
eating
majority
of
studies
focused
binge
Furthermore,
underlying
mechanisms
or
influence
factors
are
described
in
detail,
including
clock
genes,
brain
characteristics,
neuroendocrinology,
light/dark
cycle,
social
factors,
psychological
sleep
These
findings
provide
latest
chronotypes
serve
as
valuable
reference
researchers.
BACKGROUND.
The
circadian
system
entrains
behavioral
and
physiological
rhythms
to
environmental
cycles,
modern
lifestyles
disrupt
this
entrainment.
We
investigated
a
timed
exercise
intervention
phase
shift
the
internal
rhythm.
Scientific Reports,
Год журнала:
2021,
Номер
11(1)
Опубликована: Июнь 1, 2021
Abstract
The
first
COVID-19
contagion
wave
caused
unprecedented
restraining
measures
worldwide.
In
Italy,
a
period
of
generalized
lockdown
involving
home
confinement
the
entire
population
was
imposed
for
almost
two
months
(9
March–3
May
2020).
present
is
most
extensive
investigation
aimed
to
unravel
demographic,
psychological,
chronobiological,
and
work-related
predictors
sleep
disturbances
throughout
pandemic
emergency.
A
total
13,989
Italians
completed
web-based
survey
during
(25
May).
We
collected
demographic
lockdown-related
work
changes
information,
we
evaluated
quality,
insomnia
depression
symptoms,
chronotype,
perceived
stress,
anxiety
using
validated
questionnaires.
majority
respondents
reported
negative
impact
on
their
delayed
phase.
highlighted
an
alarming
prevalence
lockdown.
Main
identified
by
regression
models
were:
female
gender,
advanced
age,
being
healthcare
worker,
living
in
southern
duration,
higher
level
depression,
anxiety.
evening
chronotype
emerged
as
vulnerability
factor,
while
morning-type
individuals
showed
lower
predisposition
psychological
problems.
Finally,
working
from
associated
with
less
severe
disturbances.
Besides
confirming
role
specific
factors
developing
disorders
pandemic,
propose
that
circadian
typologies
could
react
differently
particular
reduced
social
jetlag.
Moreover,
our
results
suggest
play
protective
against
development
current
