Intratumor delivery of amino-modified graphene oxide as a multifunctional photothermal agent for efficient antitumor phototherapy

Journal of Colloid and Interface Science, Год журнала: 2023, Номер 652, С. 1108 - 1116

Опубликована: Авг. 22, 2023

Язык: Английский

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Research Progress of Photodynamic Therapy in Wound Healing: A Literature Review

Journal of Burn Care & Research, Год журнала: 2023, Номер 44(6), С. 1327 - 1333

Опубликована: Сен. 22, 2023

Light is an efficient technique that has a significant influence on contemporary medicine. Photodynamic therapy (PDT), which involves the combined action of photosensitizers (PSs), oxygen, and light, emerged as therapeutically promising method for treating broad variety solid tumors infectious diseases. minimally invasive, few side effects, lightens scars, reduces tissue loss while preserving organ structure function. In particular, PDT high healing potential wounds (PDT stimulates wound by enhancing re-epithelialization, promoting angiogenesis well modulating skin homeostasis). Wound interactions between many different processes, including coagulation, inflammation, angiogenesis, cellular migration, proliferation. Poor with diabetes or extensive burns remains difficult challenge. This review emphasizes research field summarizes PDT's role in healing, normal wounds, chronic aging wounds.

Язык: Английский

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Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice

Molecules, Год журнала: 2022, Номер 27(20), С. 6848 - 6848

Опубликована: Окт. 13, 2022

Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied in studies for the treatment of various diseases. In this context, PDT suggested as new or adjuvant to traditional cancer therapy. The mode action consists generation singlet oxygen (¹O2) and reactive species (ROS) through administration compound called photosensitizer (PS), light source, molecular (3O2). This combination generates controlled photochemical reactions (photodynamic mechanisms) produce ROS, such (¹O2), which can induce apoptosis and/or cell death induced by necrosis, degeneration tumor vasculature, stimulation antitumor immune response, induction inflammatory illuminated region. However, compounds used limit its application. biotechnological origin with photosensitizing activity association nanotechnology are being PDT, aiming at application several types but less toxicity toward neighboring tissues better absorption more aggressive cancer. review, we present involving innovatively developed PS aimed improve efficiency treatment. Specifically, focused on clinical translation natural

Язык: Английский

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Engineered microneedle systems for topical cancer therapy

Applied Materials Today, Год журнала: 2023, Номер 31, С. 101774 - 101774

Опубликована: Фев. 22, 2023

Язык: Английский

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Hydrogel design to overcome thermal resistance and ROS detoxification in photothermal and photodynamic therapy of cancer

Journal of Controlled Release, Год журнала: 2023, Номер 366, С. 142 - 159

Опубликована: Дек. 30, 2023

Язык: Английский

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