Current Opinion in Environmental Science & Health, Год журнала: 2023, Номер 33, С. 100474 - 100474
Опубликована: Май 5, 2023
Язык: Английский
Annals of Allergy Asthma & Immunology, Год журнала: 2023, Номер 132(4), С. 433 - 439
Опубликована: Ноя. 23, 2023
Язык: Английский
Процитировано
6
Pediatric Research, Год журнала: 2024, Номер 95(7), С. 1683 - 1684
Опубликована: Фев. 2, 2024
Язык: Английский
Процитировано
2
Current Allergy and Asthma Reports, Год журнала: 2024, Номер 24(5), С. 233 - 251
Опубликована: Март 16, 2024
Язык: Английский
Процитировано
2
Frontiers in Allergy, Год журнала: 2024, Номер 5
Опубликована: Май 28, 2024
Rhinitis arises from either allergic or non-allergic inflammation of the nasal mucosa, characterized by infiltration inflammatory cells into tissue and secretions, along with structural alterations in mucosa. The pathways through which air pollution affects rhinitis may diverge those affecting asthma. This article aims to review effects diverse pollutants on nose, correlation climate change pollution, how they aggravate symptoms patients rhinitis.
Язык: Английский
Процитировано
2
Molecular Immunology, Год журнала: 2024, Номер 173, С. 110 - 116
Опубликована: Авг. 6, 2024
Язык: Английский
Процитировано
2
Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2024, Номер 23(5)
Опубликована: Сен. 1, 2024
Abstract Food allergy is a significant concern for the health of humans worldwide. In addition to dietary exposure food allergens, genetic and environmental factors also play an important role in development allergy. However, only tip iceberg risk has been identified. The importance caused by orally exposed constituents, including veterinary drugs, pesticides, processed foods/derivatives, nanoparticles, microplastics, pathogens, toxins, additives, intake salt/sugar/total fat, vitamin D, therapeutic are highlighted discussed this review. Moreover, epithelial barrier hypothesis, which closely associated with occurrence allergy, introduced. Additionally, several constituents that have reported disrupt elucidated. Finally, possible mechanisms key immune cells aggravating overviewed. Further work should be conducted define specific mechanism these driving will central targeted therapy
Язык: Английский
Процитировано
2
Children, Год журнала: 2024, Номер 11(11), С. 1295 - 1295
Опубликована: Окт. 26, 2024
Asthma and food allergy are two complex allergic diseases with an increasing prevalence in childhood. They share risk factors, including atopic family history, dermatitis, allergen sensitization, T2 inflammatory pathways. Several studies have shown that children a allergy, the of developing asthma, particularly early childhood, is high. Food intake or inhalation aerosolized allergens can induce respiratory symptoms such as bronchospasm. Patients both conditions increased severe asthma exacerbations, hospitalization, mortality. The current management clinical hypersensitivity primarily involves dietary avoidance use self-injectable adrenaline for reactions. Poorly controlled limits prescription oral immunotherapy to foods, which has emerged alternative therapy managing allergies. Biological therapies effective been explored treating Omalizumab improves control and, either alone combination immunotherapy, increases threshold tolerance. Understanding interplay between crucial successful treatment approaches ameliorating patient results.
Язык: Английский
Процитировано
2
Allergy, Год журнала: 2023, Номер 79(2), С. 432 - 444
Опубликована: Окт. 7, 2023
Abstract Background Environmental exposure to peanut through non‐oral routes is a risk factor for allergy. Early‐life air pollutants, including particulate matter (PM), associated with sensitization foods unknown mechanisms. We investigated whether PM promotes environmental and the development of allergy in mouse model. Methods C57BL/6J mice were co‐exposed either urban (UPM) or diesel exhaust particles (DEP) via airways assessed anaphylaxis following challenge. Peanut‐specific CD4 + T helper (Th) cell responses characterized by flow cytometry Th cytokine production. Mice lacking select innate immune signaling genes used study mechanisms PM‐induced Results Airway co‐exposure UPM‐ DEP‐induced systemic Exposure UPM DEP triggered activation migration lung dendritic cells draining lymph nodes induction peanut‐specific cells. distinct responses, but both stimulated expansion follicular (Tfh) essential development. MyD88 was critical allergy, whereas TLR4 dispensable. Tfh‐cell differentiation depended on IL‐1 not IL‐33 signaling, neither alone necessary UPM‐mediated sensitization. Conclusion induces Tfh mice.
Язык: Английский
Процитировано
5
Environmental Health Perspectives, Год журнала: 2024, Номер 132(4)
Опубликована: Апрель 1, 2024
Evidence suggests that prenatal air pollution exposure alters DNA methylation (DNAm), which could go on to affect long-term health. It remains unclear whether DNAm alterations present at birth persist through early life. Identifying persistent changes would provide greater insight into the molecular mechanisms contributing association of with atopic diseases.
Язык: Английский
Процитировано
1
Food Chemistry, Год журнала: 2024, Номер 464, С. 141821 - 141821
Опубликована: Окт. 30, 2024
Язык: Английский
Процитировано
1