Disruption of the intestinal barrier by avermectin in carp involves oxidative stress and apoptosis and leads to intestinal inflammation DOI

Hairui Han,

Nana He,

Enzhuang Pan

и другие.

Pesticide Biochemistry and Physiology, Год журнала: 2023, Номер 195, С. 105531 - 105531

Опубликована: Июль 13, 2023

Язык: Английский

Molecular mechanism of apoptosis induced by 4-tBP in common carp (Cyprinus carpio L.) head kidneys was explored from various angles: Hippo pathway, miR-203a, oxidative stress, ER stress, and mitochondrial pathway DOI

Jiatian Liang,

Lin Xu, Chunyu Jiang

и другие.

Aquaculture, Год журнала: 2024, Номер 589, С. 740981 - 740981

Опубликована: Апрель 21, 2024

Язык: Английский

Процитировано

22
Micro-algal astaxanthin improves lambda-cyhalothrin-induced necroptosis and inflammatory responses via the ROS-mediated NF-κB signaling in lymphocytes of carp (Cyprinus carpio L.) DOI
Jingzeng Cai,

Pinnan Liu,

Xintong Zhang

и другие.

Fish & Shellfish Immunology, Год журнала: 2023, Номер 139, С. 108929 - 108929

Опубликована: Июль 4, 2023

Язык: Английский

Процитировано

38
Selenium alleviates lead-induced CIK cells pyroptosis and inflammation through IRAK1/TAK1/IKK pathway DOI
Xiunan Lv,

Mengyao Ren,

Tong Xu

и другие.

Fish & Shellfish Immunology, Год журнала: 2023, Номер 142, С. 109101 - 109101

Опубликована: Сен. 26, 2023

Язык: Английский

Процитировано

32
Chlorpyrifos-mediated mitochondrial calcium overload induces EPC cell apoptosis via ROS/AMPK/ULK1 DOI

Zhiying Miao,

Zhiruo Miao,

Shuang Feng

и другие.

Fish & Shellfish Immunology, Год журнала: 2023, Номер 141, С. 109053 - 109053

Опубликована: Сен. 1, 2023

Язык: Английский

Процитировано

26
Molecular mechanism of kidney damage caused by abamectin in carp: Oxidative stress, inflammation, mitochondrial damage, and apoptosis DOI
Xinyu Wu,

Yeyun Ma,

Xueqing Li

и другие.

Toxicology, Год журнала: 2023, Номер 494, С. 153599 - 153599

Опубликована: Июль 25, 2023

Язык: Английский

Процитировано

23
Perfluorooctane sulfonate causes pyroptosis and lipid metabolism disorders through ROS-mediated NLRP3 inflammasome activation in grass carp hepatocyte DOI

Bendong Shi,

Zhuoqi Zhang,

Jiao Xing

и другие.

Aquatic Toxicology, Год журнала: 2024, Номер 267, С. 106839 - 106839

Опубликована: Янв. 15, 2024

Язык: Английский

Процитировано

9
Intermittent mild cold acclimation ameliorates intestinal inflammation and immune dysfunction in acute cold-stressed broilers by regulating the TLR4/MyD88/NF-κB pathway DOI Creative Commons

Yanju Bi,

Haidong Wei,

Yiwen Chai

и другие.

Poultry Science, Год журнала: 2024, Номер 103(5), С. 103637 - 103637

Опубликована: Март 8, 2024

To investigate the potential protective effect of prior cold stimulation on broiler intestine induced by acute stress (ACS). A total 384 one-day-old broilers were divided into control (CON), ACS, Ⅰ (CS3+ACS), and Ⅱ (CS9+ACS) groups. Broilers in CON ACS groups reared normally, birds CS3+ACS CS9+ACS at 3℃ 9℃ below group for 5 h, respectively, alternate days from day 15 to 35. CS3+ACS, subjected 10℃ 24 h 43. Eventually, small tissues collected histopathological observation indexes detection. The results showed that intestinal all ACS-broilers exhibited inflammatory cell infiltrates, microvilli disruption, reduced villus length jejunum increased crypt depth ileum. Whereas these phenomena relatively light group. Compared group, mRNA expression TLR4/MyD88/NF-κB pathway-related genes (TLR4, MyD88, NF-κBp65, COX-2, iNOS, PTGEs, TNF-α), Th1/Th17-derived cytokines (IL-1β, IL-2, IL-8, IL-12, IFN-γ, IL-17), HSPs (HSP40, HSP60, HSP70, HSP90) was upregulated (P < 0.05), Th2-deviated (IL-4, IL-6, IL-10, IL-13) IκBα downregulated 0.05) almost ACS-broilers. most genes, cytokines, Th2-derived 0.05). Protein levels TLR4, p-p65/p65, p-IκBα/IκBα, IKK, TNF-α, IL-1β, similar their expression. concentration sIgA activities CAT, SOD, GSH-px decreased MDA H2O2 compared Therefore, caused oxidative inflammation, leading gut immune dysfunction; while mild normal rearing temperature alleviated stress-induced injure dysfunction modulating pathway broilers.

Язык: Английский

Процитировано

9
Glyphosate combined with TBBPA exposure decreased quality and flavor of common carp (Cyprinus carpio) involved inhibiting muscle growth and collagen synthesis DOI
Dong‐Xu Han,

Yanju Bi,

Tingting Yu

и другие.

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер 209, С. 106344 - 106344

Опубликована: Фев. 21, 2025

Язык: Английский

Процитировано

1
Cold stimulation causes oxidative stress, inflammatory response and apoptosis in broiler heart via regulating Nrf2/HO-1 and NF-κB pathway DOI
Haidong Wei, Tingting Li, Yong Zhang

и другие.

Journal of Thermal Biology, Год журнала: 2023, Номер 116, С. 103658 - 103658

Опубликована: Июль 14, 2023

Язык: Английский

Процитировано

20
New insights into Microalgal astaxanthin's effect on Lambda-cyhalothrin-induced lymphocytes immunotoxicity in Cyprinus carpio: Involving miRNA-194-5p-FoxO1-mediated-mitophagy and pyroptosis DOI
Jingzeng Cai, Haoyue Guan, Di Li

и другие.

Fish & Shellfish Immunology, Год журнала: 2023, Номер 141, С. 109046 - 109046

Опубликована: Сен. 1, 2023

Язык: Английский

Процитировано

20