The Co‐Occurrence of Major Depressive Disorder Among Individuals With Posttraumatic Stress Disorder: A Meta‐Analysis

Journal of Traumatic Stress, Год журнала: 2013, Номер 26(3), С. 299 - 309

Опубликована: Май 20, 2013

Although co-occurring posttraumatic stress disorder (PTSD) and major depressive (MDD) is associated with greater distress, impairment, health care utilization than PTSD alone, the magnitude of this problem uncertain. This meta-analysis aimed to estimate mean prevalence current MDD co-occurrence among individuals examine potential moderating variables (U.S. nationality, gender, trauma type, military service, referral type) that may influence rate co-occurrence. Meta-analytic findings (k = 57 studies; N 6,670 participants) revealed 52%, 95% confidence interval [48, 56], had MDD. When outliers were removed, samples interpersonal traumas demonstrated higher rates civilian natural disasters, respectively. U.S. type did not significantly account for differences in rates. high accentuates importance routinely assessing continuing research into association between these disorders.

Язык: Английский

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Classification of trauma and stressor-related disorders in DSM-5

Depression and Anxiety, Год журнала: 2011, Номер 28(9), С. 737 - 749

Опубликована: Июнь 16, 2011

This review examines the question of whether there should be a cluster disorders, including adjustment disorders (ADs), acute stress disorder (ASD), posttraumatic (PTSD), and dissociative (DDs), in section devoted to abnormal responses trauma DSM-5. Environmental risk factors, individual's developmental experience, would thus become major diagnostic consideration. The relationship these one another is examined also their other anxiety determine they are better grouped with or new specific grouping stressor-related disorders. First how have been classified since DSM-III reviewed. focus on PTSD because it has received most attention, regarding its proper placement among psychiatric diagnoses. It discussed considered an disorder, stress-induced fear circuitry internalizing disorder. Then, ASD, AD, DD from similar perspective. Evidence pro con, conclsion offered recommending inclusion this entitled "Trauma Stressor-Related Disorders." recommendation shift ASD out reflects increased recognition as precipitant, emphasizing common etiology over phenomenology. Similar considerations addressed regard AD DD.

Язык: Английский

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PATTERNS OF LIFETIME PTSD COMORBIDITY: A LATENT CLASS ANALYSIS

Depression and Anxiety, Год журнала: 2012, Номер 30(5), С. 489 - 496

Опубликована: Дек. 28, 2012

Posttraumatic stress disorder (PTSD) is associated with high rates of psychiatric comorbidity, most notably substance use disorders, major depression, and other anxiety disorders. However, little known about how these disorders cluster together among people PTSD, if clusters have distinct etiologies in terms trauma type, they confer greater burden over above PTSD alone.Utilizing Latent Class Analysis, we tested for discrete patterns lifetime comorbidity following exposure (n = 409). Diagnoses were based on the Structured Clinical Interview DSM-IV (SCID). Next, examined gender, symptom frequency, severity, interference everyday life latent classes.Three emerged: a class characterized by predominantly comorbid mood disorders; mood, anxiety, dependence; relatively pure low-comorbidity class. Individuals both classes had nearly two half times suicidal ideation, endorsed more demonstrated likelihood intimate partner abuse compared to low Men likely fall into dependent class.PTSD small number common patterns. These may represent an important area study, as differences risk possibly etiology. Implications research treatment are discussed.

Язык: Английский

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Pre-Existing High Glucocorticoid Receptor Number Predicting Development of Posttraumatic Stress Symptoms After Military Deployment

American Journal of Psychiatry, Год журнала: 2010, Номер 168(1), С. 89 - 96

Опубликована: Ноя. 16, 2010

Objective: The development of posttraumatic stress disorder (PTSD) is influenced by preexisting vulnerability factors. authors aimed at identifying a biomarker representing factor for the PTSD. To that end, they determined whether dexamethasone binding capacity leukocytes, as measure glucocorticoid receptor (GR) number, before exposure to trauma was predictor PTSD symptoms. In addition, analyzed mRNA expression GR subtypes and target genes. Method: Participants were selected from large prospective study on deployment-related disorders, in which peripheral blood mononuclear cells (PBMCs) obtained prior 1 6 months after military deployment. included armed forces personnel with high levels symptoms deployment (N=34) comparison subjects without or depressive matched age, rank, previous deployments, educational level, function during Results: Before deployment, number PBMCs significantly higher participants who developed relative subjects. Logistic regression analysis showed risk inclusion group increased 7.5-fold each increase 1,000. No differences observed GR-α, GR-P, GR-β, glucocorticoid-induced leucine zipper (GILZ), serum glucocorticoid-inducible kinase-1 (SGK-1), FKBP5. maintained Conclusions: These results demonstrate subsequent

Язык: Английский

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The association between post-traumatic stress disorder and lifetime DSM-5 psychiatric disorders among veterans: Data from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III)

Journal of Psychiatric Research, Год журнала: 2016, Номер 82, С. 16 - 22

Опубликована: Июль 4, 2016

Язык: Английский

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Describing the Mental Health Profile of First Responders: A Systematic Review

Journal of the American Psychiatric Nurses Association, Год журнала: 2017, Номер 23(3), С. 200 - 214

Опубликована: Фев. 1, 2017

First responders (FRs) are responsible for providing multiple services during various critical events. Considering the frequency, nature, and intensity of duty-related traumatic exposures, cumulative impact on FRs' mental health is paramount importance.The purpose this systematic review was to describe how trauma exposure can affect comprehensive profile FRs, including firefighters, emergency medical technicians, paramedics.Using Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines, a literature search conducted using keywords related FRs health.Twenty-seven data-based articles met eligibility criteria were included in review. Studies explored concerns, posttraumatic stress disorder, depression, suicidality, anxiety, alcohol use, sleep disturbances.Findings pose significant implications psychiatric nurses practice research, need tailored strategies meet needs at-risk population.

Язык: Английский

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Psychological burden of PTSD, depression, and their comorbidity in the U.S. veteran population: Suicidality, functioning, and service utilization

Journal of Affective Disorders, Год журнала: 2019, Номер 256, С. 633 - 640

Опубликована: Июль 2, 2019

Язык: Английский

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Co-occurring posttraumatic stress and depression symptoms after sexual assault: A latent profile analysis

Journal of Affective Disorders, Год журнала: 2013, Номер 149(1-3), С. 209 - 216

Опубликована: Март 8, 2013

Язык: Английский

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Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study

Psychoneuroendocrinology, Год журнала: 2012, Номер 37(11), С. 1822 - 1836

Опубликована: Апрель 12, 2012

Язык: Английский

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Post-traumatic stress disorder, depression, and health-related quality of life in OEF/OIF veterans

Quality of Life Research, Год журнала: 2011, Номер 21(1), С. 99 - 103

Опубликована: Апрель 22, 2011

Язык: Английский

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