Collagen-Based Biomaterials for Tissue Engineering

ACS Biomaterials Science & Engineering, Год журнала: 2023, Номер 9(3), С. 1132 - 1150

Опубликована: Фев. 17, 2023

Collagen is commonly used as a regenerative biomaterial due to its excellent biocompatibility and wide distribution in tissues. Different kinds of hybridization or cross-links are favored offer improvements satisfy various needs biomedical applications. Previous reviews have been made introduce the sources structures collagen. In addition, biological mechanical properties collagen-based biomaterials, their modification application forms, interactions with host tissues pinpointed. However, there still no review about biomaterials for tissue engineering. Therefore, we aim summarize discuss progress materials regeneration applications this review. We focus on utilization bones, cartilages, skin, dental, neuron, cornea, urological hope these experiences outcomes can provide inspiration practical techniques future development related fields. Moreover, improving directions challenges proposed well.

Язык: Английский

---

Multifunctional hydrogel with reactive oxygen species scavenging and photothermal antibacterial activity accelerates infected diabetic wound healing

Acta Biomaterialia, Год журнала: 2022, Номер 155, С. 199 - 217

Опубликована: Ноя. 17, 2022

Язык: Английский

---

An injectable, self-healing, and antioxidant collagen- and hyaluronic acid-based hydrogel mediated with gallic acid and dopamine for wound repair

Carbohydrate Polymers, Год журнала: 2023, Номер 320, С. 121231 - 121231

Опубликована: Июль 27, 2023

Язык: Английский

---

Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration

Bioactive Materials, Год журнала: 2024, Номер 35, С. 330 - 345

Опубликована: Фев. 14, 2024

The management of chronic wounds in diabetes remains challenging due to the complexity impaired wound healing, delayed susceptibility infection, and elevated risk reopening, highlighting need for effective with innovative approaches such as multifunctional hydrogels. Here, we have produced HA-DA@rhCol hydrogels consisting dopamine-modified hyaluronic acid recombinant human collagen type-III (rhCol) by oxidative coupling catechol group using H

Язык: Английский

---

Chitosan and hyaluronic-based hydrogels could promote the infected wound healing

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 232, С. 123271 - 123271

Опубликована: Янв. 14, 2023

Язык: Английский

---

Strontium Ion-Functionalized Nano-Hydroxyapatite/Chitosan Composite Microspheres Promote Osteogenesis and Angiogenesis for Bone Regeneration

ACS Applied Materials & Interfaces, Год журнала: 2023, Номер 15(16), С. 19951 - 19965

Опубликована: Апрель 12, 2023

Critical-size bone defects are an important problem in clinical practice, which usually occurs severe trauma, or tumor resection, and cannot heal completely autonomously. Implantation of grafts is often required to promote the regeneration critical-size defects. Metal ions play role human health, as they affect body's metabolism tissue function. Strontium (Sr2+) can osteogenesis angiogenesis. Herein, we prepared nano-hydroxyapatite (nHA)/chitosan (CS) composite microspheres with a uniform particle size distribution extracellular matrix-like nanofiber structure using microfluidic technology direct alkali-induced gelation. were stably added into by polydopamine (PDA) chelate metal forming repair material (nHA/CS@PDA-Sr) good bioactivity. The coordination reaction PDA effectively control release strontium avoid negative effects caused high concentration. Our vitro experiments showed that had biocompatibility coating promotes cell adhesion. slow mesenchymal stem cells osteogenic differentiation vascularization endothelial cells. In addition, injected cranial rats evaluate osseointegration vivo. results nHA/CS@PDA-Sr could defect area. This study demonstrates stimulate providing promising way for bone-defect regeneration.

Язык: Английский

---

Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies

Inflammopharmacology, Год журнала: 2024, Номер 32(1), С. 149 - 228

Опубликована: Янв. 11, 2024

Язык: Английский

---

Multifunctional PDA/ZIF8 based hydrogel dressing modulates the microenvironment to accelerate chronic wound healing by ROS scavenging and macrophage polarization

Chemical Engineering Journal, Год журнала: 2024, Номер 487, С. 150632 - 150632

Опубликована: Март 24, 2024

Язык: Английский

---

Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing

Biomolecules, Год журнала: 2022, Номер 12(12), С. 1727 - 1727

Опубликована: Ноя. 22, 2022

Chronic diabetic wounds are one of the main complications diabetes, manifested by persistent inflammation, decreased epithelialization motility, and impaired wound healing. This will not only lead to repeated hospitalization patients, but also bear expensive costs. In severe cases, it can amputation, sepsis or death. Electrospun nanofibers membranes have characteristics high porosity, specific surface area, easy functionalization structure, so they be used as a safe effective platform in treatment great application potential. article briefly reviewed pathogenesis chronic types dressings commonly used, then development electrospinning technology recent years advantages electrospun wounds. Finally, reports different nanofiber on summarized, method using multi-drug combination therapy is emphasized, which provides new ideas for

Язык: Английский

---

Nanocomposite multifunctional hyaluronic acid hydrogel with photothermal antibacterial and antioxidant properties for infected wound healing

International Journal of Biological Macromolecules, Год журнала: 2022, Номер 226, С. 870 - 884

Опубликована: Дек. 14, 2022

Язык: Английский

---