Complete genome sequence and probiotic characterization of Lactobacillus delbrueckii subsp. indicus DC-3 isolated from traditional indigenous fermented milk DOI Creative Commons

Deepti N. Chaudhari,

Jayesh J. Ahire,

Anupama N. Devkatte

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Июнь 11, 2024

Abstract In this study, Lactobacillus delbrueckii subsp. indicus DC-3 was isolated from Indian traditional indigenous fermented milk Dahi and identified using whole genome sequencing. The safety of the strain evaluated both genetic phenotypic analyses, such as presence virulence factors, mobile insertion elements, plasmids, antibiotic resistance, etc. Besides this, comprehensively investigated for in vitro probiotic traits, biofilm formation, antibacterials, exopolysaccharide (EPS) production. results, showed a single circular chromosome (3,145,837 bp) with GC content 56.73%, higher number accessory unique genes, an open pan-genome, absence virulence, transmissible resistance genes. capable surviving in gastric juice (83% viability at 3 h) intestinal (71% 6 42.5% autoaggregation, adhesion to mucin, 8.7% xylene, 8.3% Caco-2 cells. γ-hemolytic nature, usual susceptibility profile, negative results mucin gelatin degradation ensure strain. produced 10.5 g/L D-lactic acid hydrogen peroxide, inhibiting co-aggregating Escherichia coli MTCC 1687, Proteus mirabilis 425, Candida albicans ATCC 14053. addition, 90 mg/L EPS (48 formation. conclusion, study demonstrates that L. is different than previously reported strains safe potential candidate.

Язык: Английский

Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis DOI

Elizabeth Schneider,

Kenneth J. O’Riordan, Gerard Clarke

и другие.

Nature Metabolism, Год журнала: 2024, Номер 6(8), С. 1454 - 1478

Опубликована: Авг. 22, 2024

Язык: Английский

Процитировано

32
Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health DOI
Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie

и другие.

Probiotics and Antimicrobial Proteins, Год журнала: 2025, Номер unknown

Опубликована: Янв. 14, 2025

Язык: Английский

Процитировано

7
A review on probiotics and dietary bioactives: Insights on metabolic well-being, gut microbiota, and inflammatory responses DOI Creative Commons
Alice Njolke Mafe, Great Iruoghene Edo,

Osamah S. Majeed

и другие.

Food Chemistry Advances, Год журнала: 2025, Номер 6, С. 100919 - 100919

Опубликована: Фев. 11, 2025

Язык: Английский

Процитировано

4
The microbiota-gut-brain-immune interface in the pathogenesis of neuroinflammatory diseases: a narrative review of the emerging literature DOI Creative Commons
Alison Warren, Yvonne Nyavor,

Nikkia Zarabian

и другие.

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Май 16, 2024

Importance Research is beginning to elucidate the sophisticated mechanisms underlying microbiota-gut-brain-immune interface, moving from primarily animal models human studies. Findings support dynamic relationships between gut microbiota as an ecosystem (microbiome) within (host) and its intersection with host immune nervous systems. Adding this effects on epigenetic regulation of gene expression further complicates strengthens response. At heart inflammation, which manifests in a variety pathologies including neurodegenerative diseases such Alzheimer’s disease, Parkinson’s Multiple Sclerosis (MS). Observations Generally, research date limited has focused bacteria, likely due simplicity cost-effectiveness 16s rRNA sequencing, despite lower resolution inability determine functional ability/alterations. However, omits all other fungi, viruses, phages, are emerging key members microbiome. Much been done pre-clinical and/or small studies more developed parts world. The observed promising but cannot be considered reliable or generalizable at time. Specifically, causal determined currently. More followed by then little MS. data for MS encouraging this. Conclusions relevance While still nascent, interface may missing link, hampered our progress understanding, let alone preventing, managing, putting into remission diseases. Relationships must first established humans, have shown poorly translate complex physiology environments, especially when investigating microbiome where often overly simplistic. Only can robust conducted humans using mechanistic model

Язык: Английский

Процитировано

9
Gut Microbiota-Based Interventions for Parkinson’s Disease: Neuroprotective Mechanisms and Current Perspective DOI
Deepak Kumar, Mahendra Bishnoi, Kanthi Kiran Kondepudi

и другие.

Probiotics and Antimicrobial Proteins, Год журнала: 2025, Номер unknown

Опубликована: Янв. 15, 2025

Язык: Английский

Процитировано

1
Dietary index for gut microbiota is associated with stroke among US adults DOI
Jingjing Liu, Shaoqiang Huang

Food & Function, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

The dietary index for gut microbiota was inversely associated with stroke prevalence, particularly in adults aged 30 years and above.

Язык: Английский

Процитировано

1
The gut microbiota-immune-brain axis: Therapeutic implications DOI Creative Commons
Kenneth J. O’Riordan, Gerard M. Moloney, Lily Keane

и другие.

Cell Reports Medicine, Год журнала: 2025, Номер unknown, С. 101982 - 101982

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

1
Probiotics: Bridging the interplay of a healthy gut and psychoneurological well‐being DOI Creative Commons

Ashish Kumar Meher,

Biswajeet Acharya, Prafulla Kumar Sahu

и другие.

Food Bioengineering, Год журнала: 2024, Номер 3(1), С. 126 - 147

Опубликована: Март 1, 2024

Abstract The establishment of a healthy microbiota, particularly during infancy, profoundly influences psychological health and neurological function through the gut‐brain axis. This review delves into intricate connections between probiotics, gut microbiome development, their impact on disorders. Biotics, live microorganisms with proven benefits, have emerged as promising intervention, critical developmental stages. Administering specific probiotic strains ( Lactobacillus species Bifidobacterium ) in infancy has shown promise preventing alleviating disorders, implications for well‐being. bidirectional communication along axis underscores potential probiotics influencing outcomes, ranging from anxiety to neurodevelopmental Additionally, this explores emerging food engineering techniques (microencapsulation, genome editing, fermentation, protein engineering, immobilization, etc.) employed preparing probiotic‐based foods, ensuring viability targeted release gastrointestinal tract.

Язык: Английский

Процитировано

7
Along the microbiota–gut–brain axis: Use of plant polysaccharides to improve mental disorders DOI
Jiayu Gao, Ying Liang, Pu Liu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 265, С. 130903 - 130903

Опубликована: Март 19, 2024

Язык: Английский

Процитировано

6
Fibre & fermented foods: differential effects on the microbiota-gut-brain axis DOI Creative Commons
Elizabeth M. Schneider, Ramya Balasubramanian,

Aimone Ferri

и другие.

Proceedings of The Nutrition Society, Год журнала: 2024, Номер unknown, С. 1 - 16

Опубликована: Окт. 25, 2024

The ability to manipulate brain function through the communication between microorganisms in gastrointestinal tract and along gut-brain axis has emerged as a potential option improve cognitive emotional health. Dietary composition patterns have demonstrated robust capacity modulate microbiota-gut-brain axis. With their possess pre-, pro-, post-, synbiotic properties, dietary fibre fermented foods stand out potent shapers of gut microbiota subsequent signalling brain. Despite this potential, few studies directly examined mechanisms that might explain beneficial action on axis, thus limiting insight treatments for dysfunction. Herein, we evaluate differential effects from whole food sources functioning. Potential mediating health via are described. Although more multimodal research combines psychological assessments biological sampling compare each type is needed, evidence accumulated date suggests fibre, foods, and/or combination within psychobiotic diet can be cost-effective convenient approach functioning across lifespan.

Язык: Английский

Процитировано

6