Evolving Trends in Neuropsychological Profiles of Post COVID-19 Condition: A 1-Year Follow-up in Individuals with Cognitive Complaints DOI Open Access
Nicholas Grunden, Marco Calabria, Carmen García‐Sánchez

и другие.

Опубликована: Июнь 18, 2023

Background: Cognitive difficulties are reported as lasting sequelae within post COVID-19 condition. However, the chronicity of these and related factors fatigue, mood, perceived health have yet to be fully determined. More longitudinal studies needed clarify trends cognitive test performance domain impairment following onset, whether hospitalization influences outcomes. Methods: 57 participants who subjective after confirmed infection were assessed at baseline (~6 months COVID-19) follow-up (~15 later) visits. Assessments included measures across multiple domains self-report questionnaires overall health. Analyses conducted in three stages: score level (raw adjusted scores), level, stratified by status during infection. Results: Impacts on scores remain stable assessments. analyses indicate significant reductions attention executive functioning impairment, while memory is slower resolve. On measures, there was a improvement ratings follow-up. Finally, those hospitalized performed worse timed visits accounted for larger proportion cases with short-term working follow-up.Conclusions: persist both levels many condition, but evidence suggests some global attention, self-rated An effect symptoms may more discernible over time.

Язык: Английский

ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature DOI Creative Commons
Anthony L. Komaroff, W. Ian Lipkin

Frontiers in Medicine, Год журнала: 2023, Номер 10

Опубликована: Июнь 2, 2023

Some patients remain unwell for months after "recovering" from acute COVID-19. They develop persistent fatigue, cognitive problems, headaches, disrupted sleep, myalgias and arthralgias, post-exertional malaise, orthostatic intolerance other symptoms that greatly interfere with their ability to function can leave some people housebound disabled. The illness (Long COVID) is similar myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) as well persisting illnesses follow a wide variety of infectious agents following major traumatic injury. Together, these are projected cost the U.S. trillions dollars. In this review, we first compare ME/CFS Long COVID, noting considerable similarities few differences. We then in extensive detail underlying pathophysiology two conditions, focusing on abnormalities central autonomic nervous system, lungs, heart, vasculature, immune gut microbiome, energy metabolism redox balance. This comparison highlights how strong evidence each abnormality, illness, helps set priorities future investigation. review provides current road map literature biology both illnesses.

Язык: Английский

Процитировано

171
Neurocognitive Profiles in Patients With Persisting Cognitive Symptoms Associated With COVID-19 DOI Open Access
Kamini Krishnan,

Ashley Miller,

Katherine Reiter

и другие.

Archives of Clinical Neuropsychology, Год журнала: 2022, Номер 37(4), С. 729 - 737

Опубликована: Янв. 10, 2022

A subset of individuals with coronavirus disease 2019 (COVID-19) appears to develop persisting cognitive and medical symptoms. Research in the acute stages illness, generally utilizing screening measures or case reports, suggests presence deficits attention executive function. This observational study investigated functioning among persistent complaints about 5.5 months after COVID-19 infection.

Язык: Английский

Процитировано

81
Long COVID, the Brain, Nerves, and Cognitive Function DOI Creative Commons
Allison B. Reiss, C. E. Greene,

Christopher Dayaramani

и другие.

Neurology International, Год журнала: 2023, Номер 15(3), С. 821 - 841

Опубликована: Июль 6, 2023

SARS-CoV-2, a single-stranded RNA coronavirus, causes an illness known as coronavirus disease 2019 (COVID-19). Long-term complications are increasing issue in patients who have been infected with COVID-19 and may be result of viral-associated systemic central nervous system inflammation or arise from virus-induced hypercoagulable state. incite changes brain function wide range lingering symptoms. Patients often experience fatigue note fog, sensorimotor symptoms, sleep disturbances. Prolonged neurological neuropsychiatric symptoms prevalent can interfere substantially everyday life, leading to massive public health concern. The mechanistic pathways by which SARS-CoV-2 infection sequelae important subject ongoing research. Inflammation- induced blood-brain barrier permeability viral neuro-invasion direct nerve damage involved. Though the mechanisms uncertain, resulting documented numerous patient reports studies. This review examines constellation spectrum seen long COVID incorporates information on prevalence these contributing factors, typical course. Although treatment options generally lacking, potential therapeutic approaches for alleviating improving quality life explored.

Язык: Английский

Процитировано

47
Brain fog as a Long-term Sequela of COVID-19 DOI Open Access
Ali Nouraeinejad

SN Comprehensive Clinical Medicine, Год журнала: 2022, Номер 5(1)

Опубликована: Ноя. 24, 2022

Язык: Английский

Процитировано

44
COVID-19 severity is related to poor executive function in people with post-COVID conditions DOI Creative Commons
Mar Ariza,

Neus Cano,

Bàrbara Segura

и другие.

Journal of Neurology, Год журнала: 2023, Номер 270(5), С. 2392 - 2408

Опубликована: Март 20, 2023

Patients with post-coronavirus disease 2019 (COVID-19) conditions typically experience cognitive problems. Some studies have linked COVID-19 severity long-term damage, while others did not observe such associations. This discrepancy can be attributed to methodological and sample variations. We aimed clarify the relationship between outcomes determine whether initial symptomatology predict Cognitive evaluations were performed on 109 healthy controls 319 post-COVID individuals categorized into three groups according WHO clinical progression scale: severe-critical (n = 77), moderate-hospitalized 73), outpatients 169). Principal component analysis was used identify factors associated symptoms in acute-phase domains. Analyses of variance regression linear models study intergroup differences The group significantly worse than control general cognition (Montreal Assessment), executive function (Digit symbol, Trail Making Test B, phonetic fluency), social (Reading Mind Eyes test). Five components emerged from principal analysis: "Neurologic/Pain/Dermatologic" "Digestive/Headache", "Respiratory/Fever/Fatigue/Psychiatric" "Smell/ Taste" predictors Montreal Assessment scores; predicted attention working memory; verbal memory, "Respiratory/Fever/Fatigue/Psychiatric," "Neurologic/Pain/Dermatologic," "Digestive/Headache" function. severe exhibited persistent deficits Several sequelae, indicating role systemic inflammation neuroinflammation COVID-19." Study Registration: www.ClinicalTrials.gov , identifier NCT05307549 NCT05307575.

Язык: Английский

Процитировано

40
Attention and memory after COVID-19 as measured by neuropsychological tests: Systematic review and meta-analysis DOI Creative Commons
Boris B. Velichkovsky, A.Y. Razvaliaeva, Alena A. Khlebnikova

и другие.

Acta Psychologica, Год журнала: 2023, Номер 233, С. 103838 - 103838

Опубликована: Янв. 12, 2023

COVID-19 is associated with a range of sequelae, including cognitive dysfunctions as long-standing symptoms. Considering that the number people infected worldwide keeps growing, it important to understand specific domains impairments further organize appropriate rehabilitation procedures. In this study we conducted meta-analysis investigate functions impacted by COVID-19. A literature search was in Web Science, Scopus, PubMed, Academic Search Premier, Health Source: Nursing/Academic Edition, and preprint databases (OSF PsyArXiv via OSF Preprints, medRxiv, bioRxiv, Research Square). We included studies compared functioning reconvalescents healthy controls, used at least one validated neuropsychological test. Our findings show short-term memory verbal domain, possibly, visual attention, are risk reconvalescents. The impact on has yet be studied detail. future more controlled computerized tests might help deepen our understanding issue. 3360 Psychology & Medicine

Язык: Английский

Процитировано

24
Meta-analysis of Cognitive Function Following Non-severe SARS-CoV-2 Infection DOI
Tara Austin, Michael L. Thomas, Min Lü

и другие.

Neuropsychology Review, Год журнала: 2024, Номер unknown

Опубликована: Июнь 12, 2024

Язык: Английский

Процитировано

8
Cognitive reserve moderates the effect of COVID-19 on cognition: A systematic review and meta-analysis of individual participant data DOI Creative Commons

Lauren Foreman,

Brittany Child, Isaac Saywell

и другие.

Neuroscience & Biobehavioral Reviews, Год журнала: 2025, Номер unknown, С. 106067 - 106067

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Rehabilitation Strategies for Cognitive and Neuropsychiatric Manifestations of COVID-19 DOI Open Access
Summer Rolin, Ashley Chakales, Monica Verduzco‐Gutierrez

и другие.

Current Physical Medicine and Rehabilitation Reports, Год журнала: 2022, Номер 10(3), С. 182 - 187

Опубликована: Май 14, 2022

Язык: Английский

Процитировано

22
Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19 DOI Creative Commons
Boris B. Velichkovsky, A.Y. Razvaliaeva, Alena A. Khlebnikova

и другие.

Behavioural Neurology, Год журнала: 2023, Номер 2023, С. 1 - 9

Опубликована: Фев. 9, 2023

It is widely known that COVID-19 has a number of prolonged effects on general health, wellbeing, and cognitive functioning. However, studies using differentiated performance measures functions are still not spread making it hard to assess the exact get impaired. Taking into account similarities between post-COVID 'brain fog' chemofog, we hypothesized executive (EF) would be Literature search yielded six with 14 effect sizes interest; pooled size was small medium (d = -0.35). Combined narrative synthesis without comparison group, these results show EF impaired after COVID-19; although, in most cases impairment transient does seem severe. These specify picture may help discover its mechanisms ways helping people long COVID.

Язык: Английский

Процитировано

12