Enhanced physiochemical, antibacterial, and hemostatic performance of collagen-quaternized chitosan-graphene oxide sponges for promoting infectious wound healing DOI Creative Commons

Zhiwei Sun,

Keqiang Hu, Ting Wang

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131277 - 131277

Опубликована: Март 31, 2024

Bacteria-infected wound healing has attracted widespread attention in biomedical engineering. Wound dressing is a potential strategy for repairing infectious wounds. However, the development of with appropriate physiochemical, antibacterial, and hemostatic properties, remains challenging. Hence, there motivation to develop new synthetic dressings improve bacteria-infected healing. Here, we fabricate biocompatible sponge through covalent crosslinking collagen (Col), quaternized chitosan (QCS), graphene oxide (GO). The resulting Col-QCS-GO shows an elastic modulus 1.93-fold higher than Col due enhanced degree by GO incorporation. Moreover, fabricated favorable porosity (84.30 ± 3.12 %), water absorption/retention (2658.0 113.4 %/1114.0 65.7 hemostasis capacities (blood loss <50.0 mg). Furthermore, antibacterial property under near-infrared (NIR) irradiation significantly (the inhibition rates are 99.9 % S. aureus E. coli) inherent properties QCS photothermal capabilities GO. Finally, Col-QCS-GO+NIR exhibits lowest percentage area (9.05 1.42 %) at day 14 compared control group (31.61 1.76 %). This study provides insights developing innovative sponges

Язык: Английский

Developing natural polymers for skin wound healing DOI Creative Commons
Han Zhang,

Xiang Lin,

Xinyue Cao

и другие.

Bioactive Materials, Год журнала: 2023, Номер 33, С. 355 - 376

Опубликована: Ноя. 26, 2023

Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They frequently encountered various creatures, including mammals, plants, microbes. The aforementioned commonly derived from renewable sources, possess a notable level of compatibility with living organisms, limited adverse effect on environment. As result, they hold considerable significance development sustainable environmentally friendly goods. In recent times, there has advancement investigation potential uses field biomedicine, specifically relation biomaterials exhibit antibacterial antioxidant characteristics. This review provides comprehensive overview prevalent utilized biomedical domain throughout preceding two decades. this paper, we present examination components typical methods for preparation based polymers. Furthermore, summarize application polymer materials each stage skin wound repair. Finally, key findings insights into limitations current elucidate prospects their future field.

Язык: Английский

Процитировано

110

Multi-crosslinked hydrogels with strong wet adhesion, self-healing, antibacterial property, reactive oxygen species scavenging activity, and on-demand removability for seawater-immersed wound healing DOI
Yuancai Lv,

Fengying Cai,

Yuxiang He

и другие.

Acta Biomaterialia, Год журнала: 2023, Номер 159, С. 95 - 110

Опубликована: Фев. 2, 2023

Язык: Английский

Процитировано

99

A Review of Recent Progress on Collagen‐Based Biomaterials DOI
Manhui Zheng, Xuechuan Wang, Yining Chen

и другие.

Advanced Healthcare Materials, Год журнала: 2022, Номер 12(16)

Опубликована: Ноя. 15, 2022

Abstract Since the 2010s, demand for healthcare models has exceeded prevailing resources available due to rapid increase in aging population China. However, a significant gap development of biomedical materials remains, especially between China and western developed countries. Collagen is major protein extracellular matrix (ECM) been extensively applied medical fields. Collagen‐based biomaterials (CBBs) are used prepare dressings dermal substitutes, surgical sutures, plasma tissue‐engineered scaffolds, drug delivery systems; this attributed their exceptional biocompatibility, biodegradability, hypoimmunogenicity, coordination collagen hosts tissues. This review provides thorough strides CBB structures, crosslinking forming technologies, real‐world applications. First, natural origin specific structures animal‐derived non‐animal‐derived introduced compared. Second, methods technologies CBBs across board discussed. Third, several examples considered demonstrate practical use highlight cautionary notes. Finally, underlying directions from an interdisciplinary perspective outlined. aims provide comprehensive mechanisms by which can be uniquely practically as advanced biomaterial, hence providing options augmenting its

Язык: Английский

Процитировано

87

Advances in wound dressing based on electrospinning nanofibers DOI Open Access
Xiaotong Zhang, Yanxin Wang, Zhiyuan Gao

и другие.

Journal of Applied Polymer Science, Год журнала: 2023, Номер 141(1)

Опубликована: Окт. 3, 2023

Abstract In recent years, there has been a significant focus on bioactive dressings suitable for treating chronic and acute wounds. Electrospinning nanofibers are considered advanced dressing options due to their high porosity permeability air water, effective barrier properties against external pathogens, excellent resemblance the extracellular matrix wound healing skin regeneration. This article reviews advancements in application of electrospinning healing. The review begins with an overview process methods. It then explores advantages disadvantages different synthetic natural polymers used preparation dressings. discussed this include collagen, gelatin, silk fibroin, chitosan, hyaluronic acid, sodium alginate. Additionally, delves into commonly like polyvinyl alcohol, chloride, polyethylene lactone, polylactide, polyurethane applications. Furthermore, examines blending create high‐performance also incorporation functional additives, such as antimicrobial agents, growth factors, extracts, expedite tissue repair. conclusion, is emerging technology that provides unique opportunities designing more care products.

Язык: Английский

Процитировано

76

Janus Nanofiber Membranes with Photothermal‐Enhanced Biofluid Drainage and Sterilization for Diabetic Wounds DOI
Xiaojing Zhang, Nuo Yu, Qian Ren

и другие.

Advanced Functional Materials, Год журнала: 2024, Номер 34(24)

Опубликована: Фев. 16, 2024

Abstract Diabetic wounds are difficult to heal, and the key wound healing is exudate management effective disinfection. Inspired by asymmetric wettability of Janus‐structured lotus leaves, herein study has presented design a biomimetic Janus membrane that integrates unidirectional biofluid drainage photothermal‐enhanced evaporation/sterilization capabilities for accelerating diabetic healing. This prepared electrospinning polyacrylonitrile (PAN) nanofiber containing polydopamine (PDA) on surface polypropylene (PP) nonwoven membrane. Such PP/PAN x%PDA enables antigravity “pumping” water from hydrophobic PP layer hydrophilic PAN within 22 s through contact points interface. The incorporation 30 wt% PDA in imparts high photoabsorption photothermal responsiveness, facilitating continuous volatilization exudate, achieving twice displacement water, causing irreversible damage bacteria. As result, it effectively alleviates inflammation cellular fibrosis while promoting collagen deposition due its structure antibacterial properties. Impressively, such achieves an impressive closure rate 96.7% wounds, better than (59.8%) conventional bandages. Therefore, this offers promising alternative chronic wounds.

Язык: Английский

Процитировано

71

Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering DOI Creative Commons
Kai Chen, Yonghui Li, Youbin Li

и другие.

Journal of Nanobiotechnology, Год журнала: 2023, Номер 21(1)

Опубликована: Июль 24, 2023

Abstract The stimuli-responsive nanofibers prepared by electrospinning have become an ideal material due to their large specific surface area and porosity, which can respond extremely quickly external environmental incitement. As intelligent drug delivery platform, efficiently load drugs then be stimulated conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) achieve slow, on-demand targeted release, showing great potential in areas such as delivery, tumor therapy, wound dressing, tissue engineering. Therefore, this paper reviews the recent trends of electrospun platforms field biomedicine.

Язык: Английский

Процитировано

63

Recent perspective of polymeric biomaterial in tissue engineering– a review DOI
Muhammad Umar Aslam Khan,

Muhammad Azhar Aslam,

Mohd Faizal Abdullah

и другие.

Materials Today Chemistry, Год журнала: 2023, Номер 34, С. 101818 - 101818

Опубликована: Ноя. 18, 2023

Язык: Английский

Процитировано

61

Bionic structures and materials inspired by plant leaves: A comprehensive review for innovative problem-solving DOI
Haiyue Yu, Junqiu Zhang, Shuaijun Zhang

и другие.

Progress in Materials Science, Год журнала: 2023, Номер 139, С. 101181 - 101181

Опубликована: Авг. 16, 2023

Язык: Английский

Процитировано

46

Electrospinning/3D printing drug-loaded antibacterial polycaprolactone nanofiber/sodium alginate-gelatin hydrogel bilayer scaffold for skin wound repair DOI

Yongteng Song,

Qingxi Hu,

Suihong Liu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 275, С. 129705 - 129705

Опубликована: Янв. 23, 2024

Язык: Английский

Процитировано

37

Multifunctional dressings for wound exudate management DOI
Fan Feng,

Zhihui Zhao,

Jiwei Li

и другие.

Progress in Materials Science, Год журнала: 2024, Номер 146, С. 101328 - 101328

Опубликована: Июнь 14, 2024

Язык: Английский

Процитировано

30