Developing natural polymers for skin wound healing

Bioactive Materials, Journal Year: 2023, Volume and Issue: 33, P. 355 - 376

Published: Nov. 26, 2023

Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They frequently encountered various creatures, including mammals, plants, microbes. The aforementioned commonly derived from renewable sources, possess a notable level of compatibility with living organisms, limited adverse effect on environment. As result, they hold considerable significance development sustainable environmentally friendly goods. In recent times, there has advancement investigation potential uses field biomedicine, specifically relation biomaterials exhibit antibacterial antioxidant characteristics. This review provides comprehensive overview prevalent utilized biomedical domain throughout preceding two decades. this paper, we present examination components typical methods for preparation based polymers. Furthermore, summarize application polymer materials each stage skin wound repair. Finally, key findings insights into limitations current elucidate prospects their future field.

Language: Английский

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Multi-crosslinked hydrogels with strong wet adhesion, self-healing, antibacterial property, reactive oxygen species scavenging activity, and on-demand removability for seawater-immersed wound healing

Acta Biomaterialia, Journal Year: 2023, Volume and Issue: 159, P. 95 - 110

Published: Feb. 2, 2023

Language: Английский

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A Review of Recent Progress on Collagen‐Based Biomaterials

Advanced Healthcare Materials, Journal Year: 2022, Volume and Issue: 12(16)

Published: Nov. 15, 2022

Abstract Since the 2010s, demand for healthcare models has exceeded prevailing resources available due to rapid increase in aging population China. However, a significant gap development of biomedical materials remains, especially between China and western developed countries. Collagen is major protein extracellular matrix (ECM) been extensively applied medical fields. Collagen‐based biomaterials (CBBs) are used prepare dressings dermal substitutes, surgical sutures, plasma tissue‐engineered scaffolds, drug delivery systems; this attributed their exceptional biocompatibility, biodegradability, hypoimmunogenicity, coordination collagen hosts tissues. This review provides thorough strides CBB structures, crosslinking forming technologies, real‐world applications. First, natural origin specific structures animal‐derived non‐animal‐derived introduced compared. Second, methods technologies CBBs across board discussed. Third, several examples considered demonstrate practical use highlight cautionary notes. Finally, underlying directions from an interdisciplinary perspective outlined. aims provide comprehensive mechanisms by which can be uniquely practically as advanced biomaterial, hence providing options augmenting its

Language: Английский

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Advances in wound dressing based on electrospinning nanofibers

Journal of Applied Polymer Science, Journal Year: 2023, Volume and Issue: 141(1)

Published: Oct. 3, 2023

Abstract In recent years, there has been a significant focus on bioactive dressings suitable for treating chronic and acute wounds. Electrospinning nanofibers are considered advanced dressing options due to their high porosity permeability air water, effective barrier properties against external pathogens, excellent resemblance the extracellular matrix wound healing skin regeneration. This article reviews advancements in application of electrospinning healing. The review begins with an overview process methods. It then explores advantages disadvantages different synthetic natural polymers used preparation dressings. discussed this include collagen, gelatin, silk fibroin, chitosan, hyaluronic acid, sodium alginate. Additionally, delves into commonly like polyvinyl alcohol, chloride, polyethylene lactone, polylactide, polyurethane applications. Furthermore, examines blending create high‐performance also incorporation functional additives, such as antimicrobial agents, growth factors, extracts, expedite tissue repair. conclusion, is emerging technology that provides unique opportunities designing more care products.

Language: Английский

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Janus Nanofiber Membranes with Photothermal‐Enhanced Biofluid Drainage and Sterilization for Diabetic Wounds

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(24)

Published: Feb. 16, 2024

Abstract Diabetic wounds are difficult to heal, and the key wound healing is exudate management effective disinfection. Inspired by asymmetric wettability of Janus‐structured lotus leaves, herein study has presented design a biomimetic Janus membrane that integrates unidirectional biofluid drainage photothermal‐enhanced evaporation/sterilization capabilities for accelerating diabetic healing. This prepared electrospinning polyacrylonitrile (PAN) nanofiber containing polydopamine (PDA) on surface polypropylene (PP) nonwoven membrane. Such PP/PAN x%PDA enables antigravity “pumping” water from hydrophobic PP layer hydrophilic PAN within 22 s through contact points interface. The incorporation 30 wt% PDA in imparts high photoabsorption photothermal responsiveness, facilitating continuous volatilization exudate, achieving twice displacement water, causing irreversible damage bacteria. As result, it effectively alleviates inflammation cellular fibrosis while promoting collagen deposition due its structure antibacterial properties. Impressively, such achieves an impressive closure rate 96.7% wounds, better than (59.8%) conventional bandages. Therefore, this offers promising alternative chronic wounds.

Language: Английский

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Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: July 24, 2023

Abstract The stimuli-responsive nanofibers prepared by electrospinning have become an ideal material due to their large specific surface area and porosity, which can respond extremely quickly external environmental incitement. As intelligent drug delivery platform, efficiently load drugs then be stimulated conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) achieve slow, on-demand targeted release, showing great potential in areas such as delivery, tumor therapy, wound dressing, tissue engineering. Therefore, this paper reviews the recent trends of electrospun platforms field biomedicine.

Language: Английский

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Recent perspective of polymeric biomaterial in tissue engineering– a review

Materials Today Chemistry, Journal Year: 2023, Volume and Issue: 34, P. 101818 - 101818

Published: Nov. 18, 2023

Language: Английский

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Bionic structures and materials inspired by plant leaves: A comprehensive review for innovative problem-solving

Progress in Materials Science, Journal Year: 2023, Volume and Issue: 139, P. 101181 - 101181

Published: Aug. 16, 2023

Language: Английский

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Electrospinning/3D printing drug-loaded antibacterial polycaprolactone nanofiber/sodium alginate-gelatin hydrogel bilayer scaffold for skin wound repair

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 129705 - 129705

Published: Jan. 23, 2024

Language: Английский

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Multifunctional dressings for wound exudate management

Progress in Materials Science, Journal Year: 2024, Volume and Issue: 146, P. 101328 - 101328

Published: June 14, 2024

Language: Английский

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