Опубликована: Янв. 1, 2025
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 244, С. 125454 - 125454
Опубликована: Июнь 16, 2023
Язык: Английский
Процитировано
58
ACS Applied Bio Materials, Год журнала: 2024, Номер 7(5), С. 2660 - 2676
Опубликована: Май 9, 2024
Wound healing, particularly for chronic wounds, presents a considerable difficulty due to differences in biochemical and cellular processes that occur different types of wounds. Recent technological breakthroughs have notably advanced the understanding diagnostic therapeutic approaches wound healing. The evolution care has seen transition from traditional textile dressings variety alternatives, including self-healing hydrogels, hydrofibers, foams, hydrocolloids, environment responsive dressings, growth factor-based therapy, bioengineered skin substitutes, stem cell gene therapy. Technological advancements, such as 3D printing electronic (e-skin) contribute customization Despite these effectively managing wounds remains challenging. This necessitates development treatments consider performance, risk–benefit balance, cost-effectiveness. review discusses innovative strategies healing Incorporating biomarkers into coupled with corresponding biosensors drug delivery formulations, enables theranostic approach treatment Furthermore, integrating power sources user interfaces like near-field communication, radio frequency identification, Bluetooth enhances real-time monitoring on-demand delivery. It also provides thorough evaluation advantages, patient compliance, costs, durability emphasizing smart formulations their preparation methods.
Язык: Английский
Процитировано
20
Heliyon, Год журнала: 2023, Номер 9(12), С. e22520 - e22520
Опубликована: Ноя. 18, 2023
BackgroundIn addition to its barrier function, the skin plays a crucial role in maintaining stability of body's internal environment and normal physiological functions. When is damaged, it important select proper dressings as temporary barriers cover wound, which can exert significant effects on defence against microbial infection, tissue/cell functions, coordinating process wound repair regeneration. It now forms an approach clinic practice facilitate repair.Search strategiesWe conducted comprehensive literature search using online databases including PubMed, Web Science, MEDLINE, ScienceDirect, Wiley Online Library, CNKI, Wanfang Data. In addition, information was obtained from local foreign books biomaterials science traumatology.ResultsThis review focuses efficacy principles functional for anti-bacteria, anti-infection, anti-inflammation, anti-oxidation, hemostasis, healing facilitation; analyses research progress carrying living cells such fibroblasts, keratinocytes, appendage cells, stem different origins. We also summarize recent advances intelligent with respect real-time monitoring, automatic drug delivery, precise adjustment according actual microenvironment. this explores compares characteristics, advantages disadvantages, mechanisms actions, application scopes made materials.ConclusionThe dynamic acquisition analysis conditions are management prognostic evaluation. Therefore, development modern that integrate multiple have high similarity skin, highly will be focus future research, could drive efficient personalized medicine, ultimately translation health monitoring into clinical practice.
Язык: Английский
Процитировано
37
Biomimetics, Год журнала: 2024, Номер 9(5), С. 278 - 278
Опубликована: Май 7, 2024
Biomimetic materials have become a promising alternative in the field of tissue engineering and regenerative medicine to address critical challenges wound healing skin regeneration. Skin-mimetic enormous potential improve outcomes enable innovative diagnostic sensor applications. Human skin, with its complex structure diverse functions, serves as an excellent model for designing biomaterials. Creating effective coverings requires mimicking unique extracellular matrix composition, mechanical properties, biochemical cues. Additionally, integrating electronic functionality into these presents exciting possibilities real-time monitoring, diagnostics, personalized healthcare. This review examines biomimetic their role healing, well integration technologies. It discusses recent advances, challenges, future directions this rapidly evolving field.
Язык: Английский
Процитировано
15
Interdisciplinary materials, Год журнала: 2024, Номер 3(2), С. 270 - 296
Опубликована: Март 1, 2024
Abstract In recent years, wearable electrochemical biosensors have received increasing attention, benefiting from the growing demand for continuous monitoring personalized medicine and point‐of‐care medical assistance. Incorporating biosensing corresponding power supply into everyday textiles could be a promising strategy next‐generation non‐invasive comfort interaction mode with healthcare. This review starts manufacturing structural design of discusses series various biomarkers (e.g., pH, electrolytes, metabolite, cytokines) at molecular level. The fiber‐shaped or textile‐based solar cells aqueous batteries as energy harvesting storage devices are further introduced complete textiles. Finally, we discuss challenges prospects relating to sensing textile systems wearability, durability, washability, sample collection analysis, clinical validation.
Язык: Английский
Процитировано
13
npj Flexible Electronics, Год журнала: 2025, Номер 9(1)
Опубликована: Фев. 13, 2025
Язык: Английский
Процитировано
1
Materials Science and Engineering R Reports, Год журнала: 2025, Номер 164, С. 100987 - 100987
Опубликована: Апрель 2, 2025
Язык: Английский
Процитировано
1
Advanced Functional Materials, Год журнала: 2023, Номер 34(9)
Опубликована: Ноя. 20, 2023
Abstract Smart wound dressings capable of detecting, monitoring, and regulating complicated dynamic healing processes hold tremendous potential in tissue reconstruction. Micro/nanofiber‐based materials are regarded as one the most promising candidates to develop smart owing their remarkable features including architectural mimicry extracellular matrix, tunability structural assembly, diversity functionality. Herein, latest progress micro/nanoscale fiber‐based terms composition engineering, design, applications management is comprehensively reviewed. This work begins with advances fibers stimuli‐responsive fibers, shape memory conductive fibers. Then, design from conventional 2D fibrous membrane emerging 3D sponge/hydrogel thoroughly discussed. Furthermore, micro/nanofibrous drug delivery, biomechanical stimulation, electrical monitoring highlighted. Finally, article offers perspectives on existing challenges future directions for management.
Язык: Английский
Процитировано
22
Biosensors and Bioelectronics, Год журнала: 2024, Номер 258, С. 116326 - 116326
Опубликована: Апрель 22, 2024
Язык: Английский
Процитировано
8
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Авг. 1, 2024
Organic electrochemical transistors have emerged as a promising alternative to traditional 2/3 electrode setups for sensing applications, offering in-situ transduction, amplification, and noise reduction. Several of these devices are designed detect potentiometric-derived signals. However, potentiometric should be performed under open circuit potential conditions, allowing the system reach thermodynamic equilibrium. This criterion is not met by conventional organic transistors, where voltages or currents directly applied interface, that is, gate electrode. In this work, we introduce an transistor configuration called potentiometric‑OECT (pOECT), which maintains conditions. The pOECT exhibits higher response than 2-electrode setup offers greater accuracy, response, stability compared transistors. Additionally, it allows implementation high-impedance electrodes gate/sensing surfaces, all without compromising overall device size. translation transistor-based sensor technologies limited unreliable sensing. Here, authors propose eliminates measurement inaccuracies associated with sensors.
Язык: Английский
Процитировано
8