Microchemical Journal,
Journal Year:
2023,
Volume and Issue:
191, P. 108836 - 108836
Published: May 12, 2023
The
sensing
of
theophylline
(TP)
and
uric
acid
(UA)
is
important
for
the
diagnosis
treatment
diseases
in
early
stages.
While
first
proofs
show
potential
electrochemical
sensors,
simultaneous
detection
TP
UA
still
not
satisfactory.
Herein
we
present
an
sensor
showing
high
sensitivity
selectivity
two
purine
derivatives,
blood
serum.
Key
this
a
multinary
nanocomposite
which
was
specially
designed
purpose
based
on
titania
nanoparticles,
copper
oxide,
boron-doped
reduced
graphene
Au
nanoparticles
as
also
modification
supporting
carbon
electrode
with
2-amino-5-mercapto-1,3,4-thiadiazole
through
electropolymerization.
study
showed
that
improves
electrochemically
active
surface
area
electron
transfer
rate
sensor,
together
boosts
current
response
strongly.
It
could
be
shown
provides
excellent
linear
relationship
between
0.5
nM
10.0
µM
1.0
µM.
Detection
limits
0.18
0.36
results
TP,
respectively.
1.27
μA
µM−1
cm−2
1.06
TP.
Additionally,
method
used
measurements
real
serum,
demonstrated
applicability
device.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
7(5), P. 2660 - 2676
Published: May 9, 2024
Wound
healing,
particularly
for
chronic
wounds,
presents
a
considerable
difficulty
due
to
differences
in
biochemical
and
cellular
processes
that
occur
different
types
of
wounds.
Recent
technological
breakthroughs
have
notably
advanced
the
understanding
diagnostic
therapeutic
approaches
wound
healing.
The
evolution
care
has
seen
transition
from
traditional
textile
dressings
variety
alternatives,
including
self-healing
hydrogels,
hydrofibers,
foams,
hydrocolloids,
environment
responsive
dressings,
growth
factor-based
therapy,
bioengineered
skin
substitutes,
stem
cell
gene
therapy.
Technological
advancements,
such
as
3D
printing
electronic
(e-skin)
contribute
customization
Despite
these
effectively
managing
wounds
remains
challenging.
This
necessitates
development
treatments
consider
performance,
risk–benefit
balance,
cost-effectiveness.
review
discusses
innovative
strategies
healing
Incorporating
biomarkers
into
coupled
with
corresponding
biosensors
drug
delivery
formulations,
enables
theranostic
approach
treatment
Furthermore,
integrating
power
sources
user
interfaces
like
near-field
communication,
radio
frequency
identification,
Bluetooth
enhances
real-time
monitoring
on-demand
delivery.
It
also
provides
thorough
evaluation
advantages,
patient
compliance,
costs,
durability
emphasizing
smart
formulations
their
preparation
methods.
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(12), P. e22520 - e22520
Published: Nov. 18, 2023
BackgroundIn
addition
to
its
barrier
function,
the
skin
plays
a
crucial
role
in
maintaining
stability
of
body's
internal
environment
and
normal
physiological
functions.
When
is
damaged,
it
important
select
proper
dressings
as
temporary
barriers
cover
wound,
which
can
exert
significant
effects
on
defence
against
microbial
infection,
tissue/cell
functions,
coordinating
process
wound
repair
regeneration.
It
now
forms
an
approach
clinic
practice
facilitate
repair.Search
strategiesWe
conducted
comprehensive
literature
search
using
online
databases
including
PubMed,
Web
Science,
MEDLINE,
ScienceDirect,
Wiley
Online
Library,
CNKI,
Wanfang
Data.
In
addition,
information
was
obtained
from
local
foreign
books
biomaterials
science
traumatology.ResultsThis
review
focuses
efficacy
principles
functional
for
anti-bacteria,
anti-infection,
anti-inflammation,
anti-oxidation,
hemostasis,
healing
facilitation;
analyses
research
progress
carrying
living
cells
such
fibroblasts,
keratinocytes,
appendage
cells,
stem
different
origins.
We
also
summarize
recent
advances
intelligent
with
respect
real-time
monitoring,
automatic
drug
delivery,
precise
adjustment
according
actual
microenvironment.
this
explores
compares
characteristics,
advantages
disadvantages,
mechanisms
actions,
application
scopes
made
materials.ConclusionThe
dynamic
acquisition
analysis
conditions
are
management
prognostic
evaluation.
Therefore,
development
modern
that
integrate
multiple
have
high
similarity
skin,
highly
will
be
focus
future
research,
could
drive
efficient
personalized
medicine,
ultimately
translation
health
monitoring
into
clinical
practice.
Biomimetics,
Journal Year:
2024,
Volume and Issue:
9(5), P. 278 - 278
Published: May 7, 2024
Biomimetic
materials
have
become
a
promising
alternative
in
the
field
of
tissue
engineering
and
regenerative
medicine
to
address
critical
challenges
wound
healing
skin
regeneration.
Skin-mimetic
enormous
potential
improve
outcomes
enable
innovative
diagnostic
sensor
applications.
Human
skin,
with
its
complex
structure
diverse
functions,
serves
as
an
excellent
model
for
designing
biomaterials.
Creating
effective
coverings
requires
mimicking
unique
extracellular
matrix
composition,
mechanical
properties,
biochemical
cues.
Additionally,
integrating
electronic
functionality
into
these
presents
exciting
possibilities
real-time
monitoring,
diagnostics,
personalized
healthcare.
This
review
examines
biomimetic
their
role
healing,
well
integration
technologies.
It
discusses
recent
advances,
challenges,
future
directions
this
rapidly
evolving
field.
Interdisciplinary materials,
Journal Year:
2024,
Volume and Issue:
3(2), P. 270 - 296
Published: March 1, 2024
Abstract
In
recent
years,
wearable
electrochemical
biosensors
have
received
increasing
attention,
benefiting
from
the
growing
demand
for
continuous
monitoring
personalized
medicine
and
point‐of‐care
medical
assistance.
Incorporating
biosensing
corresponding
power
supply
into
everyday
textiles
could
be
a
promising
strategy
next‐generation
non‐invasive
comfort
interaction
mode
with
healthcare.
This
review
starts
manufacturing
structural
design
of
discusses
series
various
biomarkers
(e.g.,
pH,
electrolytes,
metabolite,
cytokines)
at
molecular
level.
The
fiber‐shaped
or
textile‐based
solar
cells
aqueous
batteries
as
energy
harvesting
storage
devices
are
further
introduced
complete
textiles.
Finally,
we
discuss
challenges
prospects
relating
to
sensing
textile
systems
wearability,
durability,
washability,
sample
collection
analysis,
clinical
validation.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(9)
Published: Nov. 20, 2023
Abstract
Smart
wound
dressings
capable
of
detecting,
monitoring,
and
regulating
complicated
dynamic
healing
processes
hold
tremendous
potential
in
tissue
reconstruction.
Micro/nanofiber‐based
materials
are
regarded
as
one
the
most
promising
candidates
to
develop
smart
owing
their
remarkable
features
including
architectural
mimicry
extracellular
matrix,
tunability
structural
assembly,
diversity
functionality.
Herein,
latest
progress
micro/nanoscale
fiber‐based
terms
composition
engineering,
design,
applications
management
is
comprehensively
reviewed.
This
work
begins
with
advances
fibers
stimuli‐responsive
fibers,
shape
memory
conductive
fibers.
Then,
design
from
conventional
2D
fibrous
membrane
emerging
3D
sponge/hydrogel
thoroughly
discussed.
Furthermore,
micro/nanofibrous
drug
delivery,
biomechanical
stimulation,
electrical
monitoring
highlighted.
Finally,
article
offers
perspectives
on
existing
challenges
future
directions
for
management.
