The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly

The Lancet Microbe, Год журнала: 2022, Номер 3(12), С. e969 - e983

Опубликована: Сен. 29, 2022

Язык: Английский

---

Cross-feeding in the gut microbiome: Ecology and mechanisms

Cell Host & Microbe, Год журнала: 2023, Номер 31(4), С. 485 - 499

Опубликована: Апрель 1, 2023

Язык: Английский

---

A catalogue of 1,167 genomes from the human gut archaeome

Nature Microbiology, Год журнала: 2021, Номер 7(1), С. 48 - 61

Опубликована: Дек. 30, 2021

The human gut microbiome plays an important role in health, but its archaeal diversity remains largely unexplored. In the present study, we report analysis of 1,167 nonredundant genomes (608 high-quality genomes) recovered from gastrointestinal tract, sampled across 24 countries and rural urban populations. We identified previously undescribed taxa including 3 genera, 15 species 52 strains. Based on distinct genomic features, justify split Methanobrevibacter smithii clade into two separate species, with one represented by 'Candidatus intestini'. Patterns derived 28,581 protein clusters showed significant associations sociodemographic characteristics such as age groups lifestyle. additionally show that archaea are characterized specific functional adaptations to host carry a complex virome. Our work expands our current understanding archaeome provides large genome catalogue for future analyses decipher impact physiology.

Язык: Английский

---

Promises of microbiome-based therapies

Journal of Hepatology, Год журнала: 2022, Номер 76(6), С. 1379 - 1391

Опубликована: Май 16, 2022

Язык: Английский

---

A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

Signal Transduction and Targeted Therapy, Год журнала: 2024, Номер 9(1)

Опубликована: Сен. 23, 2024

Язык: Английский

---

Archaea, tiny helpers of land plants

Computational and Structural Biotechnology Journal, Год журнала: 2020, Номер 18, С. 2494 - 2500

Опубликована: Янв. 1, 2020

Archaea are members of most microbiomes. While archaea highly abundant in extreme environments, they less and diverse association with eukaryotic hosts. Nevertheless, a substantial constituent plant-associated ecosystems the aboveground belowground phytobiome. Only few studies have investigated role plant health its potential symbiosis ecosystems. This review discusses recent progress identifying how contribute to traits such as growth, adaptation abiotic stresses, immune activation. We synthesized functional molecular data on archaea, including root colonization volatile emission activate systemic immunity. These represent paradigm shift our understanding plant-microbiota interactions.

Язык: Английский

---

Methanogenic archaea in the human gastrointestinal tract

Nature Reviews Gastroenterology & Hepatology, Год журнала: 2022, Номер 19(12), С. 805 - 813

Опубликована: Сен. 1, 2022

Язык: Английский

---

Factors shaping the abundance and diversity of the gut archaeome across the animal kingdom

Nature Communications, Год журнала: 2022, Номер 13(1)

Опубликована: Июнь 10, 2022

Archaea are common constituents of the gut microbiome humans, ruminants, and termites but little is known about their diversity abundance in other animals. Here, we analyse sequencing quantification data archaeal bacterial 16S rRNA genes from 250 species animals covering a large taxonomic spectrum. We detect presence archaea 175 animal belonging to invertebrates, fish, amphibians, birds, reptiles mammals. identify five dominant lineages, corresponding Methanobrevibacter, Methanosphaera, Methanocorpusculum, Methanimicrococcus "Ca. Methanomethylophilaceae". Some clades, notably within associated certain hosts, suggesting specific adaptations. The non-methanogenic lineage Nitrososphaeraceae (Thaumarchaeota) frequently present samples, although at low abundance, may have also adapted environment. Host phylogeny, diet type, fibre content, intestinal tract physiology major drivers archaeome overall more influenced by these factors than that bacteria. Methanogens reducing methyl-compounds with H

Язык: Английский

---

Characteristics of microbial community composition and its relationship with carbon, nitrogen and sulfur in sediments

The Science of The Total Environment, Год журнала: 2021, Номер 795, С. 148848 - 148848

Опубликована: Июль 3, 2021

Язык: Английский

---

Predicting drug-microbiome interactions with machine learning

Biotechnology Advances, Год журнала: 2021, Номер 54, С. 107797 - 107797

Опубликована: Июль 11, 2021

Язык: Английский

---