Russian Chemical Reviews,
Год журнала:
2021,
Номер
90(8), С. 895 - 1107
Опубликована: Апрель 20, 2021
The
interest
in
functional
supramolecular
systems
for
the
design
of
innovative
materials
and
technologies,
able
to
fundamentally
change
world,
is
growing
at
a
high
pace.
huge
array
publications
that
appeared
recent
years
global
literature
calls
systematization
structural
trends
inherent
formation
these
revealed
different
molecular
platforms
practically
useful
properties
they
exhibit.
attention
concentrated
on
topics
related
are
actively
explored
institutes
universities
Russia
last
10–15
years,
such
as
chemistry
host–guest
complexes,
crystal
engineering,
self-assembly
self-organization
solutions
interfaces,
biomimetics
machines
devices.
bibliography
includes
1714
references.
Metal-organic
frameworks
(MOFs)
are
an
interesting
and
useful
class
of
coordination
polymers,
constructed
from
metal
ion/cluster
nodes
functional
organic
ligands
through
bonds,
have
attracted
extensive
research
interest
during
the
past
decades.
Due
to
unique
features
diverse
compositions,
facile
synthesis,
easy
surface
functionalization,
high
areas,
adjustable
porosity,
tunable
biocompatibility,
MOFs
been
widely
used
in
hydrogen/methane
storage,
catalysis,
biological
imaging
sensing,
drug
delivery,
desalination,
gas
separation,
magnetic
electronic
devices,
nonlinear
optics,
water
vapor
capture,
etc.
Notably,
with
rapid
development
synthetic
methods
functionalization
strategies,
smart
MOF-based
nanocomposites
advanced
bio-related
properties
designed
fabricated
meet
growing
demands
MOF
materials
for
biomedical
applications.
This
work
outlines
synthesis
recent
advances
fields,
including
cargo
(drugs,
nucleic
acids,
proteins,
dyes)
delivery
cancer
therapy,
bioimaging,
antimicrobial,
biosensing,
biocatalysis.
The
prospects
challenges
field
also
discussed.
Chemical Society Reviews,
Год журнала:
2020,
Номер
49(4), С. 1144 - 1172
Опубликована: Янв. 1, 2020
This
review
presents
comprehensive
discussions
on
the
recent
development
in
supramolecular
materials
based
luminogens
with
aggregation-induced
emission
(AIE)
characteristics.
Chemical Reviews,
Год журнала:
2020,
Номер
120(13), С. 6070 - 6123
Опубликована: Май 19, 2020
Covalent
polymers
connected
by
non-covalent
interactions
constitute
a
fascinating
set
of
materials
known
as
supramolecular
polymer
networks
(SPNs).
A
key
feature
SPNs
is
that
the
underlying
covalent
endow
resulting
self-assembled
with
features,
such
structural
and
mechanical
integrity,
good
processability,
recyclability,
stimuli-responsiveness,
self-healing,
shape
memory,
are
not
recapitulated
in
case
classic
systems.
The
unique
nature
derives
from
controlled
marriage
traditional
macrocycle-based
host-guest
interactions.
As
consequence,
polymeric
have
played
important
roles
number
diverse
fields,
including
science,
chemistry,
biomedical
materials,
information
storage
technology.
In
this
Review,
we
summarize
advances
made
area
functional
SPNs,
focus
on
original
literature
reports
appearing
past
five
years.
treatment
organized
according
to
used
produce
various
SPNs.
role
backbones
also
discussed.
Chemical Reviews,
Год журнала:
2020,
Номер
120(24), С. 13480 - 13544
Опубликована: Ноя. 25, 2020
Compartmentalization
of
the
aqueous
space
within
a
cell
is
necessary
for
life.
In
similar
fashion
to
nanometer-scale
compartments
in
living
systems,
synthetic
water-soluble
coordination
cages
(WSCCs)
can
isolate
guest
molecules
and
host
chemical
transformations.
Such
thus
show
promise
biological,
medical,
environmental,
industrial
domains.
This
review
highlights
examples
three-dimensional
WSCCs,
offering
perspectives
so
as
enhance
their
design
applications.
Strategies
are
presented
that
address
key
challenges
preparation
soluble
stable
water.
The
peculiarities
binding
media
examined,
highlighting
amplified
water,
changing
properties,
recognition
specific
molecular
targets.
properties
WSCC
hosts
associated
with
biomedical
applications,
use
vessels
carry
out
reactions
also
presented.
These
sketch
blueprint
new
metal–organic
containers
solution,
well
guidelines
engineering
applications
Advanced Materials,
Год журнала:
2019,
Номер
32(6)
Опубликована: Дек. 13, 2019
The
clinical
application
of
chemotherapy
is
impeded
by
the
unsatisfactory
efficacy
and
severe
side
effects.
Chemodynamic
therapy
(CDT)
has
emerged
as
an
efficient
strategy
for
cancer
treatment
utilizing
Fenton
chemistry
to
destroy
cells
converting
endogenous
H2
O2
into
highly
toxic
reactive
oxygen
species.
Apart
from
chemotherapeutic
effect,
cisplatin
able
act
artificial
enzyme
produce
CDT
through
cascade
reactions,
thus
remarkably
improving
anti-tumor
outcomes.
Herein,
organic
theranostic
nanomedicine
(PTCG
NPs)
constructed
with
high
loading
capability
using
epigallocatechin-3-gallate
(EGCG),
phenolic
platinum(IV)
prodrug
(Pt-OH),
polyphenol
modified
block
copolymer
(PEG-b-PPOH)
building
blocks.
stability
PTCG
NPs
during
circulation
stems
their
strong
metal-polyphenol
coordination
interactions,
drug
release
realized
after
cellular
internalization.
activated
elevates
intracellular
level
reactions.
This
further
utilized
species
catalyzed
iron-based
reaction.
In
vitro
in
vivo
investigations
demonstrate
that
combination
chemodynamic
achieves
excellent
anticancer
efficacy.
Meanwhile,
systemic
toxicity
faced
platinum-based
drugs
avoided
this
nanoformulation.
work
provides
a
promising
develop
advanced
therapy.
Chemical Society Reviews,
Год журнала:
2021,
Номер
50(8), С. 5086 - 5125
Опубликована: Янв. 1, 2021
Some
infectious
or
malignant
diseases
such
as
cancers
are
seriously
threatening
the
health
of
human
beings
all
over
world.
The
commonly
used
antibiotic
therapy
cannot
effectively
treat
these
within
a
short
time,
and
also
bring
about
adverse
effects
drug
resistance
immune
system
damage
during
long-term
systemic
treatment.
Phototherapy
is
an
emerging
antibiotic-free
strategy
to
diseases.
Upon
light
irradiation,
phototherapeutic
agents
can
generate
cytotoxic
reactive
oxygen
species
(ROS)
induce
temperature
increase,
which
leads
death
targeted
cells.
These
two
kinds
killing
strategies
referred
photodynamic
(PDT)
photothermal
(PTT),
respectively.
So
far,
many
photo-responsive
have
been
developed.
Among
them,
metal-organic
framework
(MOF)
becoming
one
most
promising
materials
because
its
structure
chemical
compositions
be
easily
modulated
achieve
specific
functions.
MOFs
intrinsic
ability
under
rational
design
MOF
construction,
serve
carrier
therapeutic
agents,
owing
tunable
porosity.
provide
feasibility
for
various
combined
therapies
targeting
methods,
improves
efficiency
phototherapy.
In
this
review,
we
firstly
investigated
principles
phototherapy,
comprehensively
summarized
recent
advances
in
PDT,
PTT
synergistic
therapy,
from
construction
modification.
We
expect
that
our
demonstration
will
shed
on
future
development
field,
it
step
closer
clinical
trials.
Chemical Reviews,
Год журнала:
2018,
Номер
119(3), С. 1666 - 1762
Опубликована: Дек. 28, 2018
Organic/inorganic
nanohybrids
have
attracted
widespread
interests
due
to
their
favorable
properties
and
promising
applications
in
biomedical
areas.
Great
efforts
been
made
design
fabricate
versatile
nanohybrids.
Among
different
organic
components,
diverse
polymers
offer
unique
avenues
for
multifunctional
systems
with
collective
properties.
This
review
focuses
on
the
design,
properties,
of
organic/inorganic
fabricated
from
inorganic
nanoparticles
polymers.
We
begin
a
brief
introduction
variety
strategies
fabrication
functional
Then
functions
are
discussed,
including
parts,
synergistic
morphology-dependent
self-assembly
After
that,
current
situations
applied
imaging,
therapy,
imaging-guided
therapy
demonstrated.
Finally,
we
discuss
prospect
highlight
challenges
opportunities
future
investigations.
Chemical Society Reviews,
Год журнала:
2021,
Номер
50(4), С. 2839 - 2891
Опубликована: Янв. 1, 2021
Supramolecular
cancer
nanotheranostics
have
shown
promising
potentials
in
early-stage
diagnosis
and
personal
therapy.
Herein,
we
summarize
the
progress
of
supramolecular
provide
guidance
for
designing
new
targeted
theranostic
agents.
